Date: 05 Dec 2013

Contrast Agents in Radiology

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Abstract

To noninvasively diagnose disease and to describe response to therapy regarding morphology (e.g., size, structure) and (patho)physiology (e.g., blood perfusion) as well as cell function optimal image contrast is key. In our various body compartments in vivo contrast can be altered and improved by changing its intensity and distribution over time. This imaging fortune has been established by various contrast agents typically administered intravenously. Imaging methods in the field of ultrasound, magnetic resonance imaging, as well as computed tomography are continuously being improved by safe, valid, and efficient contrast agents. New targeted and specific agents are in the pipeline, but there are still a few more steps to go to reach market approval.