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Epigenetic Aspects of Chronic Diseases pp 107–119Cite as

Epigenetics of Rheumatoid Arthritis

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Abstract

Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic inflammation of the joints that leads to progressive and irreversible destruction of bone and cartilage, with joint pain, stiffness, and swelling as predominant symptoms. It is one of the most common autoimmune diseases affecting approximately 1% of the world’s population.

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Author information

Authors and Affiliations

  1. Division of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

    Aleksander M. Grabiec

Authors
  1. Aleksander M. Grabiec
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  2. Paul P. Tak
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  3. Kris A. Reedquist
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Corresponding author

Correspondence to Aleksander M. Grabiec .

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Editors and Affiliations

  1. , General Hospital, University of Southampton, Southampton, SO16 6YD, United Kingdom

    Helmtrud I. Roach

  2. Health Center, Dept. Pharmacology, University of Connecticut, Farmington Ave. 263, Farmington, 06030-6125, Connecticut, USA

    Felix Bronner

  3. Developmental Origins Health and Disease, University of Southampton, Southampton, SO16 6YD, United Kingdom

    Richard O.C. Oreffo

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© 2011 Springer London

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Grabiec, A.M., Tak, P.P., Reedquist, K.A. (2011). Epigenetics of Rheumatoid Arthritis. In: Roach, H., Bronner, F., Oreffo, R. (eds) Epigenetic Aspects of Chronic Diseases. Springer, London. https://doi.org/10.1007/978-1-84882-644-1_7

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