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Stress and Cardiovascular Disease pp 89–110Cite as

Haemostatic Effects of Stress

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Abstract

The three major components of haemostasis – platelet activation, blood coagulation and fibrinolysis – are finely tuned to maintain flowing blood in the normal blood vessel, and yet stop bleeding and repair wounds when vessels are damaged. When the system is perturbed, arterial thrombosis may cause myocardial infarction (MI), stroke and other acute ischaemic events. Acute coronary events are often caused by atherosclerotic plaque rupture triggered by haemodynamic factors that increase wall stress and inflammatory weakening of the fibrous cap that covers the plaque.

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Authors and Affiliations

  1. Department of Medicine, Solna, Clinical Pharmacology Unit, Karolinska Institute, Karolinska University Hospital/Solna, Stockholm, Sweden

    Paul Hjemdahl

  2. Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland

    Roland von Känel

  3. Division of Psychosomatic Medicine, Inselspital, Bern University Hospital, Bern, Switzerland

    Roland von Känel

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  1. Paul Hjemdahl
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  2. Roland von Känel
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Correspondence to Paul Hjemdahl .

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Editors and Affiliations

  1. Karolinska Hospital, Dept. Clinical Pharmacology, Karolinska Institute, Stockholm, 171 76, Sweden

    Paul Hjemdahl

  2. St Georges Hospital Medical School, Dept. Psychology, University of London, Cranmer Terrace, London, SW17 0RE, United Kingdom

    Andrew Steptoe

  3. Sahlgrenska University Hospital/Östra, Göteborg, SE-416 85, Sweden

    Annika Rosengren

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Hjemdahl, P., von Känel, R. (2011). Haemostatic Effects of Stress. In: Hjemdahl, P., Steptoe, A., Rosengren, A. (eds) Stress and Cardiovascular Disease. Springer, London. https://doi.org/10.1007/978-1-84882-419-5_6

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  • DOI: https://doi.org/10.1007/978-1-84882-419-5_6

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