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Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities pp 90–105Cite as

Adaptive Behavior Change and Dementia in Down Syndrome: Case Classification Using the Adaptive Behavior Scale

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References

  1. Stratford B (1989) Down’s Syndrome: Past, Present and Future. Penguin.London:

    Google Scholar 

  2. Stratford B (1982) Down’s syndrome at the Court of Mantua. J Family Med: Matern Child Health 7: 250–4.

    Google Scholar 

  3. Down JLH (1866) Observations on an ethnic classification of idiots. Lond Hosp Rep 3: 259–62.

    Google Scholar 

  4. Lejeune J, Gautier M, and Turpin R (1959) Study of somatic chromosomes from 9 mongoloid children. CR Hebd Seances Acad Sci 248: 1721–2.

    CAS  Google Scholar 

  5. Lejeune J, Gautier M, and Turpin R (1959) A study of somatic chromosomes in nine infants with mongolism. CR Acad Sci (Paris) 240: 1026–7.

    Google Scholar 

  6. Morbidity and Mortality Weekly Report (2006) Improved national prevalence estimates for 18 selected major birth defects—United States, 1999–2001. In: CDC, ed. 1301–5 .

    Google Scholar 

  7. American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders, 3rd edn., revised. Washington, DC: American Psychiatric Association.

    Google Scholar 

  8. Ackerman S (1992) The role of the brain in mental illness. Discovering the Brain. National Academy Press, Washington, DC: 46–66.

    Google Scholar 

  9. Graeber MB, Kosel S, Egensperger R,et al. (1997) Rediscovery of the case described by Alois Alzheimer in 1911: Historical, histological and molecular genetic analysis. Neurogenetics 1: 73–80.

    Article  PubMed  CAS  Google Scholar 

  10. Alzheimer A, Stelzmann RA, Schnitzlein HN,et al. (1995) An English translation of Alzheimer’s 1907 paper, “Uber eine eigenartige Erkankung der Hirnrinde”. Clin Anat 8: 429–31.

    Article  PubMed  CAS  Google Scholar 

  11. Fraser J and Mitchell A (1876) Kalmuc idiocy: Report of a case with autopsy with notes on sixty-two cases. J Ment Sci 22: 169–79.

    Google Scholar 

  12. Jervis GA (1948) Early senile dementia in mongoloid idiocy. Am J Psychiatry 105: 102–6.

    PubMed  CAS  Google Scholar 

  13. National Institute on Aging (2006) Aging Under the Microscope: A Biological Quest. National Institutes of Health 51.

    Google Scholar 

  14. Fogelman CJ and Nihira K (1975) AAMD Adaptive Behavior Scale: The American Association on Mental Deficiency .

    Google Scholar 

  15. Heber R (1961) A manual on terminology and classification in mental retardation. Am J Mental Deficiency (Monogr Suppl, 2nd Ed ).

    Google Scholar 

  16. Grossman HE (1977) A Manual on Terminology and Classification in Mental Retardation, 3rd American Association on Mental Retardation.Washington, DC:

    Google Scholar 

  17. Schalock RL (1999) The concept of adaptive behavior. Schalock RL, Adaptive Behavior and Its Measurement: Implications for the Field of Mental Retardation. American Association on Mental Retardation, Washington, DC: 1–5.

    Google Scholar 

  18. Leland H (1991) Adaptive behavior scales. Matson JL and Mulick JA, Handbook of Mental Retardation, 2nd Pergamon Press, New York: 211–21.

    Google Scholar 

  19. Leland H, Shellhaas M, Nihira K,et al. (1967) Adaptive behavior: A new dimension in the qualification of the mentally retarded. Ment Retard Abstr 4: 359–87.

    Google Scholar 

  20. Nihira K, Foster R, Shellhaas M,et al. (1974) AAMD Adaptive Behavior Scale. American Association on Mental Deficiency.Washington, DC:

    Google Scholar 

  21. Nihira K, Leland H, and Lambert N (1993) American Association on Mental R. ABS-RC: 2, AAMR Adaptive Behavior Scale Residential and Community: PRO-ED.

    Google Scholar 

  22. Academy N (2002) The role of adaptive behavior assessment. Reschly DJ, Myers TG, and Hartel CR, Mental Retardation: Determining Eligibility for Social Security Benefits. National Academies Press, Washington, DC: 141–207.

    Google Scholar 

  23. Meyer CE, Nihira K, Zetlin A (1979) The measurement of adaptive behavior. Ellis NR, Handbook of Mental Deficiency, Psychological Theory and Research, 2nd Lawrence Erlbaum Associates, Hillsdale, NJ: 431–81.

    Google Scholar 

  24. Isett RD and Spreat S (1979) Test-retest and interrater reliability of the AAMD adaptive behavior scale. Am J Ment Defic 84: 93–5.

    PubMed  CAS  Google Scholar 

  25. Spreat S (1980) The adaptive behavior scale: a study of criterion validity. Am J Ment Defic 85: 61–8.

    PubMed  CAS  Google Scholar 

  26. Knapp S and Salend SJ (1983) Adapting the Adaptive Behavior Scale. Ment Retard 21: 63–7.

    PubMed  CAS  Google Scholar 

  27. Malamud N (1972) Neuropathology of organic brain syndromes associated with aging. Aging Brain 63–87.

    Google Scholar 

  28. Lott IT and Head E (2005) Alzheimer disease and Down syndrome: factors in pathogenesis. Neurobiol Aging. 26: 383–9.

    Article  PubMed  CAS  Google Scholar 

  29. Silverman W, Schupf N, Zigman W,et al. (2004). Dementia in adults with mental retardation: assessment at a single point in time. Am J Ment Retard 109: 111–25.

    Article  PubMed  Google Scholar 

  30. Anastasi A (1988) Psychological Testing, 6th Macmillan.New York:

    Google Scholar 

  31. Salagaras S and Nettelbeck T (1983) Adaptive behavior of mentally retarded adolescents attending school. Am J Ment Defic 88: 57–68.

    PubMed  CAS  Google Scholar 

  32. Salagaras S and Nettelbeck T (1984) Adaptive behavior of mentally retarded adults in work-preparation settings. Am J Ment Defic 88: 437–41.

    PubMed  CAS  Google Scholar 

  33. Miniszek NA (1983) Development of Alzheimer disease in Down syndrome individuals. Am J Ment Defic 87: 377–85.

    PubMed  CAS  Google Scholar 

  34. Collacott RA (1992) The effect of age and residential placement on adaptive behaviour of adults with Down’s syndrome. Br J Psychiatry 161: 675–9.

    Article  PubMed  CAS  Google Scholar 

  35. Cooper SA and Collacott RA (1995) The effect of age on language in people with Down’s syndrome. J Intellect Disabil Res 39: 197–200.

    Article  PubMed  CAS  Google Scholar 

  36. Prasher VP (1996) The effect of age on language in people with Down’s syndrome. J Intellect Disabil Res 40: 484–5.

    Article  PubMed  Google Scholar 

  37. Collacott RA (1993) Epilepsy, dementia and adaptive behaviour in Down’s syndrome. J Intellect Disabil Res 37: 153–60.

    Article  PubMed  Google Scholar 

  38. Amatniek JC, Hauser WA, DelCastillo-Castaneda C,et al. (2006) Incidence and predictors of seizures in patients with Alzheimer’s disease. Epilepsia 47: 867–72.

    Article  PubMed  Google Scholar 

  39. Fenner ME, Hewitt KE, and Torpy DM (1987) Down’s syndrome: Intellectual and behavioural functioning during adulthood. J Ment Defic Res 31: 241–9.

    PubMed  Google Scholar 

  40. Urv TK, Zigman WB, and Silverman W (2003) Maladaptive behaviors related to adaptive decline in aging adults with mental retardation. Am J Ment Retard 108: 327–39.

    Article  PubMed  Google Scholar 

  41. Zigman WB, Schupf N, Urv T,et al. (2002) Incidence and temporal patterns of adaptive behavior change in adults with mental retardation. Am J Ment Retard 107: 161–74.

    Article  PubMed  Google Scholar 

  42. Visser FE, Aldenkamp AP, van Huffelen AC,et al. (1997) Prospective study of the prevalence of Alzheimer-type dementia in institutionalized individuals with Down syndrome. Am J Ment Retard 101: 400–12.

    PubMed  CAS  Google Scholar 

  43. Henderson S (1998) Epidemiology of dementia. Ann Med Intern (Paris) 149: 181–6.

    CAS  Google Scholar 

  44. Borjesson-Hanson A, Edin E, Gislason T,et al. (2004) The prevalence of dementia in 95 year olds. Neurology 28 (63):2436–8.

    Google Scholar 

  45. Prasher VP, Chung MC, and Haque MS (1998) Longitudinal changes in adaptive behavior in adults with Down syndrome: Interim findings from a longitudinal study. Am J Ment Retard 103: 40–6.

    Article  PubMed  CAS  Google Scholar 

  46. Perneczky R, Pohl C, Sorg C,et al. (2006) Impairment of activities of daily living requiring memory or complex reasoning as part of the MCI syndrome. Int J Geriatr Psychiatry 21: 158–62.

    Article  PubMed  Google Scholar 

  47. Ball SL, Holland AJ, Hon J,et al. (2006) Personality and behaviour changes mark the early stages of Alzheimer’s disease in adults with Down’s syndrome: Findings from a prospective population-based study. Int J Geriatr Psychiatry 21: 661–73.

    Article  PubMed  Google Scholar 

  48. Prasher VP and Chung MC (1996) Causes of age-related decline in adaptive behavior of adults with Down syndrome: Differential diagnoses of dementia. Am J Ment Retard 101: 175–83.

    PubMed  CAS  Google Scholar 

  49. Prasher VP (1996) Is there a prodromal phase to Alzheimer’s dementia in adults with Down syndrome? Br J Develop Disabil 42: 192–7.

    Google Scholar 

  50. Prasher VP, Krishnan DJ, Clarke DJ,et al. (1994) The assessment of dementia in people with Down syndrome: Changes in adaptive behaviour. Br J Dev Disabil XL: 120–30.

    Google Scholar 

  51. Prasher VP, Adams C, and Holder R (2003) Long term safety and efficacy of donepezil in the treatment of dementia in Alzheimer’s disease in adults with Down syndrome: Open label study. Int J Geriatr Psychiatry 18: 549–51.

    Article  PubMed  CAS  Google Scholar 

  52. Prasher VP, Huxley A, and Haque MS (2002) A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Down syndrome and Alzheimer’s disease—pilot study. Int J Geriatr Psychiatry 17: 270–8.

    Article  PubMed  Google Scholar 

  53. Zigman WB, Schupf N, Devenny DA,et al. (2004) Incidence and prevalence of dementia in elderly adults with mental retardation without Down syndrome. Am J Ment Retard 109: 126–41.

    Article  PubMed  Google Scholar 

  54. Evenhuis HM (1996) Further evaluation of the Dementia Questionnaire for Persons with Mental Retardation (DMR). J Intellect Disabil Res 40: 369–73.

    Article  PubMed  Google Scholar 

  55. Evenhuis HM (1992) Evaluation of a screening instrument for dementia in ageing mentally retarded persons. J Intellect Disabil Res 36: 337–47.

    Article  PubMed  Google Scholar 

  56. Reiss S and Valenti-Hein D (1994) Development of a psychopathology rating scale for children with mental retardation. J Consult Clin Psychol 62: 28–33.

    Article  PubMed  CAS  Google Scholar 

  57. Dunn L and Dunn L (1981) Peabody Picture Vocabulary Test-Revised. American Guidance Service.Circle Pines, MN:

    Google Scholar 

  58. Haxby JV (1989) Neuropsychological evaluation of adults with Down’s syndrome: Patterns of selective impairment in non-demented old adults. J Ment Defic Res 33: 193–210.

    PubMed  Google Scholar 

  59. Wisniewski K and Hill A, (1985) Clinical Aspects of Dementia in Mental Retardation and Developmental Disabilities. Brookes.Baltimore, MD:

    Google Scholar 

  60. Albert M and Cohen C (1992) The Test for Severe Impairment: An instrument for the assessment of patients with severe cognitive dysfunction. J Am Geriatr Soc 40: 449–53.

    PubMed  CAS  Google Scholar 

  61. McCarthy D (1972) Scales of Children’s Abilities. Psychological Corporation.San Antonio, TX:

    Google Scholar 

  62. Beery K and Bukenia N (1989) Developmental Test of Visual-Motor Integration. Modern Curriculum Press.Cleveland, OH:

    Google Scholar 

  63. Wechsler D (1974) Wechsler Intelligence Scale for Children-Revised. Psychological Corporation.New York, NY:

    Google Scholar 

  64. Buschke H (1973) Selective reminding for analysis of memory and learning. J Verbal Learn Verbal Behav 12: 543–50.

    Article  Google Scholar 

  65. Aylward EH, Burt DB, Thorpe LU,et al. (1997) Diagnosis of dementia in individuals with intellectual disability. J Intellect Disabil Res 41: 152–64.

    Article  PubMed  Google Scholar 

  66. Burt DB and Aylward EH (2000) Test battery for the diagnosis of dementia in individuals with intellectual disability. Working Group for the Establishment of Criteria for the Diagnosis of Dementia in Individuals with Intellectual Disability. J Intellect Disabil Res 44: 175–80.

    Article  PubMed  Google Scholar 

  67. Silverman W, Devenny DA, Krinsky-McHale SJ, et al. (2006) Aging, dementia and cognitive decline in adults with Down syndrome. In: 39th Annual Gatlinburg Conference on Research and Theory in Intellectual and Developmental Disabilities, San Diego.

    Google Scholar 

  68. Lott IT (1982) Down’s syndrome, aging, and Alzheimer’s disease: A clinical review. Ann N Y Acad Sci 396: 15–27.

    Article  PubMed  CAS  Google Scholar 

  69. Goldgaber D, Lerman MI, McBride WO,et al. (1987) Isolation, characterization, and chromosomal localization of human brain cDNA clones coding for the precursor of the amyloid of brain in Alzheimer’s disease, Down’s syndrome and aging. J Neural Transm Suppl 24: 23–8.

    PubMed  CAS  Google Scholar 

  70. Prasher VP, Farrer MJ, Kessling AM,et al. (1998) Molecular mapping of Alzheimer-type dementia in Down’s syndrome. Ann Neurol 43: 380–3.

    Article  PubMed  CAS  Google Scholar 

  71. Lai F and Williams RS (1989) A prospective study of Alzheimer disease in Down syndrome. Arch Neurol 46: 849–53.

    PubMed  CAS  Google Scholar 

  72. Zigman WB, Schupf N, Sersen E,et al. (1996) Prevalence of dementia in adults with and without Down syndrome. Am J Ment Retard 100: 403–12.

    PubMed  CAS  Google Scholar 

  73. Holland AJ, Hon J, Huppert FA,et al. (1998) Population-based study of the prevalence and presentation of dementia in adults with Down’s syndrome. Br J Psychiatry 172: 493–8.

    Article  PubMed  CAS  Google Scholar 

  74. Zigman W, Jenkins E, Mehta P, et al. (2000) Alzheimer’s disease, survival, and genetics in the “oldest old” with Down syndrome. In: Down Syndrome Research Foundation (Canada)/National Down Syndrome Society (US) New Directions in Down Syndrome Research Conference, Toronto, Canada.

    Google Scholar 

  75. Jackson CV, Holland AJ, Williams CA,et al. (1988) Vitamin E and Alzheimer’s disease in subjects with Down’s syndrome. J Ment Defic Res 32: 479–84.

    PubMed  Google Scholar 

  76. Schupf N, Kapell D, Lee JH,et al. (1996) Onset of dementia is associated with apolipoprotein E epsilon4 in Down’s syndrome. Ann Neurol 40: 799–801.

    Article  PubMed  CAS  Google Scholar 

  77. Cosgrave M, Tyrrell J, Dreja H,et al. (1996) Lower frequency of apolipoprotein E4 allele in an “elderly” Down’s syndrome population. Biol Psychiatry 15: 811–3.

    Article  Google Scholar 

  78. Folin M, Baiguera S, Conconi MT,et al. (2003) The impact of risk factors of Alzheimer’s disease in the Down syndrome. Int J Mol Med 11: 267–70.

    PubMed  Google Scholar 

  79. Schupf N, Pang D, Patel BN,et al. (2003) Onset of dementia is associated with age at menopause in women with Down’s syndrome. Ann Neurol 54: 433–8.

    Article  PubMed  Google Scholar 

  80. Jenkins EC, Velinov MT, Ye L, et al. (2005) Telomere shortening in T lymphocytes of older individuals with Down syndrome and dementia. Neurobiol Aging. Jul 18 .

    Google Scholar 

  81. Schupf N, Winsten S, Patel B,et al. (2006) Bioavailable estradiol and age at onset of Alzheimer’s disease in postmenopausal women with Down syndrome. Neurosci Lett 406: 298–302.

    Article  PubMed  CAS  Google Scholar 

  82. Zigman WB, Schupf N, Jenkins EC,et al. (2007) Cholesterol level, statin use and Alzheimer’s disease in adults with Down syndrome. Neurosci Lett 11: 279–84.

    Article  Google Scholar 

  83. National Institute on Aging (2003) Alzheimer’s Disease: Unraveling the Mystery. U.S. Department of Human Services, National Institutes of Health.

    Google Scholar 

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Acknowledgments

Supported by NIH grants R01-AG014763, P01-HD35897, R01-HD37425, by the National Down Syndrome Society in collaboration with the NICHD, and by NYS through its Office of Mental Retardation and Developmental Disabilities.

Authors
  1. W.B. Zigman
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  2. N. Schupf
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  3. T.K. Urv
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  4. W. Silverman
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    Zigman, W., Schupf, N., Urv, T., Silverman, W. (2009). Adaptive Behavior Change and Dementia in Down Syndrome: Case Classification Using the Adaptive Behavior Scale. In: Prasher, V. (eds) Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities. Springer, London. https://doi.org/10.1007/978-1-84800-249-4_6

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    • DOI: https://doi.org/10.1007/978-1-84800-249-4_6

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