Abstract
Against the background of increasing health care expenditures, coronary heart disease has a significant impact on global economics as a leading cause of disability and loss of productivity. Over 70 million Americans suffer from cardiovascular disease, contributing to approximately 900,000 deaths annually. Coronary heart disease and cerebrovascular disease account for more than six million hospitalizations every year in the USA alone [1]. As treatment outcomes of acute coronary syndromes continue to improve, more patients survive the acute event and thus their disease state changes into a chronic phase. The increasing incidence of cardiovascular risk factors such as diabetes mellitus and obesity combined with the increasing number of revascularization procedures and decreased cardiac mortality rate have transformed the demographic of patients with ischemic heart disease into a steadily increasing population of patients with chronic, and occasionally refractory, angina pectoris.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Preventing heart disease and stroke addressing the Nation’s leading killers 2005. Centers for Disease Control, 2005. http://www.cdc.gov/nccdphp/aag/aag_cvd.htm. Accessed 29 Apr 2005.
World Health Organization. World health report 2004: changing history. Geneva: World Health Organization; 2004.
Gaziano JM. Global burden of cardiovascular disease. In: Zipes, editor. Braunwald’s heart disease: a textbook of cardiovascular medicine, 7th ed. Philadelphia, PA: W.B. Saunders; 2005.
Ergin A, Muntner P, Sherwin R, He J. Secular trends in cardiovascular disease mortality, incidence, and case fatality rates in adults in the United States. Am J Med. 2004;117(4):219–27.
Rosamond WD, Chambless LE, Folsom AR, et al. Trends in the incidence of myocardial infarction and in mortality due to coronary heart disease, 1987–1994. N Engl J Med. 1998;339(13):861–7.
McGovern PG, Pankow JS, Shahar E, et al. Recent trends in acute coronary heart disease – mortality, morbidity, medical care, and risk factors. N Engl J Med. 1996;334(14):884–90.
Fox CS, Evans JC, Larson MG, Kannel WB, Levy D. Temporal trends in coronary heart disease mortality and sudden cardiac death from 1950–1999: the Framingham heart study. Circulation. 2004;110(5):522–7.
Critchley J, Liu J, Zhao D, Wei W, Capewell S. Explaining the increase in coronary heart disease mortality in Beijing between 1984 and 1999. Circulation. 2004;110(10):1236–44.
Chobanian AV, Bakris GL, Black HR, et al. The seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA. 2003;289(19):2560–71.
Vasan RS, Beiser A, Seshadri S, et al. Residual lifetime risk for developing hypertension in middle-aged women and men: the Framingham heart study. JAMA. 2002;287(8):1003–10.
American Heart Association. Heart disease and stroke statistics – 2005 update. Dallas: American Heart Association; 2005.
National Institutes of Health. Morbidity and mortality: 2004 chart book on cardiovascular, lung, and blood diseases. Bethesda: National Heart, Lung, and Blood Institute; 2004.
Wild SMB, Roglic G, Green AM, Sicree RM, King HM. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27(5):1047–53.
Sobel BE, Frye R, Detre KM. Burgeoning dilemmas in the management of diabetes and cardiovascular disease: rationale for the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial. Circulation. 2003;107(4):636–42.
National Center for Health Statistics, 2005. http://www.cdc.gov/nchs/nhis.htm. Accessed 29 Apr 2005.
Gregg EW, Cheng YJ, Cadwell BL, et al. Secular trends in cardiovascular disease risk factors according to body mass index in US adults. JAMA. 2005;293(15):1868–74.
Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination survey. JAMA. 2002;287(3):356–9.
Arciero TJ, Jacobsen SJ, Reeder GS, et al. Temporal trends in the incidence of coronary disease. Am J Med. 2004;117(4):228–33.
ACC/AHA guideline update for the management of patients with chronic stable angina: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee to update the 1999 guidelines for the management of patients with chronic stable angina). 2002. Accessed at: http://www.acc.org/clinical/guidelines/stable/stable.pdf.
Sajadieh A, Nielsen OW, Rasmussen V, Hein HO, Hansen JF. Prevalence and prognostic significance of daily-life silent myocardial ischaemia in middle-aged and elderly subjects with no apparent heart disease. Eur Heart J. 2005;26(14):1402–9.
Cohn PF, Fox KM, Daly C. Silent myocardial ischemia. Circulation. 2003;108(10):1263–77.
Lampe FC, Whincup PH, Wannamethee SG, Shaper AG, Walker M, Ebrahim S. The natural history of prevalent ischaemic heart disease in middle-aged men. Eur Heart J. 2000;21(13):1052–62.
Lampe FC, Whincup PH, Shaper AG, Wannamethee SG, Walker M, Ebrahim S. Variability of angina symptoms and the risk of major ischemic heart disease events. Am J Epidemiol. 2001;153(12):1173–82.
Rihal CS, Raco DL, Gersh BJ, Yusuf S. Indications for coronary artery bypass surgery and percutaneous coronary intervention in chronic stable angina: review of the evidence and methodological considerations. Circulation. 2003;108(20):2439–45.
Eagle KA, Guyton RA, Davidoff R, et al. ACC/AHA guidelines for coronary artery bypass graft surgery: executive summary and recommendations: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee to revise the 1991 guidelines for coronary artery bypass graft surgery). Circulation. 1999;100(13):1464–80.
Henderson RA, Pocock SJ, Clayton TC, et al. Seven-year outcome in the RITA-2 trial: coronary angioplasty versus medical therapy. J Am Coll Cardiol. 2003;42(7):1161–70.
Pfisterer M, Trial of invasive versus Medical therapy in Elderly patients Investigators. Long-term outcome in elderly patients with chronic angina managed invasively versus by optimized medical therapy: four-year follow-up of the randomized Trial of Invasive Versus Medical Therapy in Elderly Patients (TIME). Circulation. 2004;110(10):1213–8.
Hueb W, Soares PR, Gersh BJ, et al. The medicine, angioplasty, or surgery study (MASS-II): a randomized, controlled clinical trial of three therapeutic strategies for multivessel coronary artery disease: one-year results. J Am Coll Cardiol. 2004;43(10):1743–51.
Bucher HC, Hengstler P, Schindler C, Guyatt GH. Percutaneous transluminal coronary angioplasty versus medical treatment for non-acute coronary heart disease: meta-analysis of randomised controlled trials. BMJ. 2000;321(7253):73–7.
Hjemdahl P, Eriksson SV, Held C, Forslund L, Nasman P, Rehnqvist N. Favourable long-term prognosis in stable angina pectoris: an extended follow-up of the Angina Prognosis Study in Stockholm (APSIS). Heart. 2005;92(2):177–82. doi:hrt.2004.057703.
Jabbour S, Young-Xu Y, Graboys TB, et al. Long-term outcomes of optimized medical management of outpatients with stable coronary artery disease. Am J Cardiol. 2004;93(3):294–9.
Mannheimer C, Camici P, Chester MR, et al. The problem of chronic refractory angina. Report from the ESC Joint Study Group on the treatment of refractory angina. Eur Heart J. 2002;23(5):355–70.
Kim MC, Kini A, Sharma SK. Refractory angina pectoris: mechanism and therapeutic options. J Am Coll Cardiol. 2002;39(6):923–34.
Life expectancy at birth, 65 and 85 years of age, by sex and race: United States, selected years 1900–2002. Center for Disease Control. http://209.217.72.34/aging/TableViewer/tableView.aspx. Accessed 29 Apr 2005.
Kandzari DE, Lam LC, Eisenstein EL, et al. Advanced coronary artery disease: appropriate end points for trials of novel therapies. Am Heart J. 2001;142(5):843–51.
Caracciolo EA, Davis KB, Sopko G, et al. Comparison of surgical and medical group survival in patients with left main coronary artery disease: long-term CASS experience. Circulation. 1995;91(9):2325–34.
da Rocha CAS, Rodrigues Dassa NP, Monassa Pittella FJ, et al. High mortality associated with precluded coronary artery bypass surgery caused by severe distal coronary artery disease. Circulation. 2005;112(9 suppl):I-328–31.
Mukherjee D, Bhatt DL, Roe MT, Patel V, Ellis SG. Direct myocardial revascularization and angiogenesis – how many patients might be eligible? Am J Cardiol. 1999;84(5):598–600.
Mukherjee D, Comella K, Bhatt DL, Roe MT, Patel V, Ellis SG. Clinical outcome of a cohort of patients eligible for therapeutic angiogenesis or transmyocardial revascularization. Am Heart J. 2001;142(1):72–4.
Stone GW, Teirstein PS, Rubenstein R, et al. A prospective, multicenter, randomized trial of percutaneous transmyocardial laser revascularization in patients with nonrecanalizable chronic total occlusions. J Am Coll Cardiol. 2002;39(10):1581–7.
Allen KB, Dowling RD, Fudge TL, et al. Comparison of transmyocardial revascularization with medical therapy in patients with refractory angina. N Engl J Med. 1999;341(14):1029–36.
Liao L, Sarria-Santamera A, Matchar DB, et al. Meta-analysis of survival and relief of angina pectoris after transmyocardial revascularization. Am J Cardiol. 2005;95(10):1243–5.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer-Verlag London Limited
About this chapter
Cite this chapter
Lavi, S., Kandzari, D.E., Barsness, G.W. (2012). Epidemiology of Cardiovascular Disease and Refractory Angina. In: Barsness, G., Holmes, D. (eds) Coronary Artery Disease. Springer, London. https://doi.org/10.1007/978-1-84628-712-1_1
Download citation
DOI: https://doi.org/10.1007/978-1-84628-712-1_1
Published:
Publisher Name: Springer, London
Print ISBN: 978-1-84628-460-1
Online ISBN: 978-1-84628-712-1
eBook Packages: MedicineMedicine (R0)