Abstract
The history of Neuropathology is inseparable from that of Neurosurgery. Since the creation of Cushing’s Tumor Registry, it has been apparent that neurosurgeons should understand the elements of diagnostic neuropathology. Over the past few decades, there have been extensive developments in histologic tools requiring lengthy specialized training for neuropathologists. The new diagnostic imaging techniques enable clinicians to discover and locate numerous lesions other than tumors and abscesses. The imaging advances also allow the evolution of the lesions to be studied. This chapter focuses on the neuropathologic approaches that neurosurgical trainees should understand. The following three questions should be answered, (1) How is histo-pathologic diagnosis made? (2) How can one understand the changing diagnostic terminology? (3) What are the limitations of histopathologic diagnosis of surgical specimens?
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Fulton J. Harvey Cushing. A biography. Springfield, Ill., Charles C. Thomas, 1946.
Bailey P, Cushing H. A classification of the tumors of the glioma group on a histogenetic basis with a correlation study of prognosis. Philadelphia, Lippincott, 1926.
Shaw CM, Alvord EC Jr. Congenital arachnoid cysts and their differential diagnosis. In: Vinken PJ, Bruyn GW, editors. Handbook of clinical neurology, vol 31: congenital malformations of the brain and skull, part II. Amsterdam: North-Holland Publishing Co, 1977; 75–135.
Zulch KJ. Brain tumors, their biology and pathology. Berlin Heidelberg New York: Springer, 1986.
Bigner DD, McLendon RE, Bruner JM. Russell & Rubinstein’s pathology of tumors of the nervous system, 6th edn. London Sydney Auckland: Arnold; 1998.
Berger PC, Scheithauer BW. Atlas of tumor pathology (vol 10, Tumors of the central nervous system). Washington DC: AFIP, 1994.
Asa SL. Atlas of tumor pathology, vol 22: tumors of the pituitary gland. Washington DC: AFIP, 1998.
Scheithauer BW, Woodruff JM, Erlandson RA. Atlas of tumor pathology, vol 24: tumors of the peripheral nervous system. Washington DC: AFIP, 1999.
Alvord, EC Jr. Is necrosis helpful in the grading of gliomas? Editorial. J Neuropathol Exp Neurol 1992;51:127–32.
Graham DI, Lantos PL (editors). Greenfield’s neuropathology, 6th edn. London Sydney Auckland: Arnold, 2002.
Mandonnet E, Delattre JY, Tanguy ML, Swanson KR, Carpenter AF, Duffau H et al. Continuous growth of mean tumor diameter in a subset of WHO Grade II gliomas. Ann Neurol 2003;53:524–8.
Swanson KR, Alvord EC Jr, Murray JD. Virtual brain tumors (gliomas) enhance the reality of medical imaging and highlight inadequacies of current therapy. Br J Cancer 2002;86:14–18.
Woodward DE, Cook J, Tracqui P, Cruywagen GC, Murray JD, Alvord EC Jr. A mathematical model of glioma growth: the effect of extent of surgical resection. Cell Prolif 1996;29:269–88.
Mork SJ, Lindegaard K-F, Halvorsen TB, Lehmann EH, Solgaard T, Hatlevoli R et al. Oligodendroglioma: incidence and biological behavior in a defined population. J Neurosurg 1985;63:881–9.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2006 Springer-Verlag London Limited
About this chapter
Cite this chapter
Shaw, CM., Alvord, E.C. (2006). Neuropathology. In: Moore, A.J., Newell, D.W. (eds) Tumor Neurosurgery. Springer Specialist Surgery Series. Springer, London. https://doi.org/10.1007/978-1-84628-294-2_3
Download citation
DOI: https://doi.org/10.1007/978-1-84628-294-2_3
Publisher Name: Springer, London
Print ISBN: 978-1-84628-291-1
Online ISBN: 978-1-84628-294-2
eBook Packages: MedicineMedicine (R0)