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Trichomoniasis

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Part of the book series: Current Clinical Practice ((CCP))

Abstract

Trichomoniasis (Trich) is one of the most commonly acquired STDs. “Trich” is often considered a “nuisance” infection, with symptoms of vaginal pruritis, dysuria, and, occasionally, pelvic pain. More is now known about potential health consequences of Trichomonas vaginalis. In addition to complications following certain gynecologic procedures, infection with this protozoan is associated with co-infection of other STDs and increases the individual’s risk of acquired HIV if exposed. Clinicians are charged to identify, educate, and treat patients and partners about this “not so benign” STD.

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References

  1. Cates Jr W. Estimates of the incidence and prevalence of sexually transmitted diseases in the United States. American Social Health Association Panel. Sex Transm Dis. 1999;26:S2–7.

    Article  PubMed  Google Scholar 

  2. Gerbase AC, Rowley JT, Heymann DH, Berkley SF, Piot P. Global prevalence and incidence estimates of selected curable STDs. Sex Transm Infect. 1998;74:S12–6.

    PubMed  Google Scholar 

  3. World Health Organization. Sexually Transmitted Infections Fact Sheet. Geneva, Switzerland: World Health Organization. 2004. Available from: www.who.int/reproductive-health/rtis/docs/sti_factsheet_2004.pdf. Accessed April 18, 2005.

  4. Soper D. Trichomoniasis: under control or undercontrolled? Am J Obstet Gynecol. 2004;190:281–90.

    Article  PubMed  Google Scholar 

  5. Spence MR, Hollander DH, Smith J, McCaig L, Sewell D, Brockman M. The clinical and laboratory diagnosis of Trichomonas vaginalis infection. Sex Transm Dis. 1980;7:168–71.

    Article  PubMed  CAS  Google Scholar 

  6. Petrin D, Delgaty K, Bhatt R, Garber G. Clinical and microbiological aspects of Trichomonas vaginalis. Clin Microbiol Rev. 1998;11:300–17.

    PubMed  CAS  Google Scholar 

  7. Horowitz BJ, Mårdh P-A, editors. Vaginitis and Vaginosis. New York, NY: Wiley-Liss; 1999.

    Google Scholar 

  8. Hook III EW. Trichomonas vaginalis—no longer a minor STD. Sex Transm Dis. 1999;26:388–9.

    Article  PubMed  Google Scholar 

  9. Laga M, Manoka A, Kivuvu M, et al. Non-ulcerative sexually transmitted diseases as risk factors for HIV-1 transmission in women: results from a cohort study. AIDS. 1993;7:95–102.

    Article  PubMed  CAS  Google Scholar 

  10. Hobbs MM, Kazembe P, Reed AW, et al. Trichomonas vaginalis as a cause of urethritis in Malawian men. Sex Transm Dis. 1999;26:381–7.

    Article  PubMed  CAS  Google Scholar 

  11. Thomason JL, Gelbart SM. Trichomonas vaginalis. Obstet Gynecol. 1989;74:536–41.

    PubMed  CAS  Google Scholar 

  12. Latif AS, Mason PR, Marowa E. Urethral trichomoniasis in men. Sex Transm Dis. 1987;14:9–11.

    Article  PubMed  CAS  Google Scholar 

  13. Mason PR, Forman L. Serological survey of trichomoniasis in Zimbabwe Rhodesia. Cent Afr J Med. 1980;26:6–8.

    PubMed  CAS  Google Scholar 

  14. Gardner HL, Dukes CD. Haemophilus vaginalis vaginitis: a newly defined specific infection previously classified non-specific vaginitis. Am J Obstet Gynecol. 1955;69:962–76.

    PubMed  CAS  Google Scholar 

  15. Sweet RL, Gibbs RS. Infectious diseases of the female genital tract. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2002. p. 339–40.

    Google Scholar 

  16. Lara-Torre E, Pinkerton JS. Accuracy of detection of Trichomonas vaginalis organisms on a liquid-based Papanicolaou smear. Am J Obstet Gynecol. 2003;188:354–6.

    Article  PubMed  Google Scholar 

  17. Ledger WJ, Monif GR. A growing concern: inability to diagnose vulvovaginal infections correctly. Obstet Gynecol. 2004;103:782–4.

    Article  PubMed  Google Scholar 

  18. Krieger JN, Tam MR, Stevens CE, et al. Diagnosis of trichomoniasis. Comparison of conventional wet-mount examination with cytologic studies, cultures, and monoclonal antibody staining of direct specimens. JAMA. 1988;259:1223–7.

    Article  PubMed  CAS  Google Scholar 

  19. van Der Schee C, van Belkum A, Zwijgers L, et al. Improved diagnosis of Trichomonas vaginalis infection by PCR using vaginal swabs and urine specimens compared to diagnosis by wet mount microscopy, culture, and fluorescent staining. J Clin Microbiol. 1999;37:4127–30.

    Google Scholar 

  20. Lobo TT, Feijo G, Carvalho SE, et al. A comparative evaluation of the Papanicolaou test for the diagnosis of trichomoniasis. Sex Transm Dis. 2003;30:694–9.

    Article  PubMed  Google Scholar 

  21. Borchardt KA, Li Z, Zhang MZ, Shing H. An in vitro metronidazole susceptibility test for trichomoniasis using the InPouch TV test. Genitourin Med. 1996;72:132–5.

    PubMed  CAS  Google Scholar 

  22. Weston TE, Nicol CS. Natural history of trichomonal infection in males. Br J Vener Dis. 1963;39:251–7.

    PubMed  CAS  Google Scholar 

  23. Durel P, Roiron V, Siboulet A, Borel LJ. Systemic treatment of human trichomoniasis with a derivative of nitro-imidazole, 8823 RP. Br J Vener Dis. 1960;36:21–6.

    PubMed  CAS  Google Scholar 

  24. Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2006. MMWR 2006; 55(RR-11):52–54. Available from: http://www.cdc.gov/std/treatment/. Accessed Nov. 24, 2006.

  25. Sobel JD, Nyirjesy P, Brown W. Tinidazole therapy for metronidazole-resistant vaginal trichomoniasis. Clin Infect Dis. 2001;33:1341–6.

    Article  PubMed  CAS  Google Scholar 

  26. Spence MR, Harwell TS, Davies MC, Smith JL. The minimum single oral metronidazole dose for treating trichomoniasis: a randomized, blinded study. Obstet Gynecol. 1997;89:699–703.

    Article  PubMed  CAS  Google Scholar 

  27. Hager WD, Brown ST, Kraus SJ, Kleris GS, Perkins GJ, Henderson M. Metronidazole for vaginal trichomoniasis. Seven-day vs single-dose regimens. JAMA. 1980;244:1219–20.

    Article  PubMed  CAS  Google Scholar 

  28. Tidwell BH, Lushbaugh WB, Laughlin MD, Cleary JD, Finley RW. A double-blind placebo-controlled trial of single-dose intravaginal versus single-dose oral metronidazole in the treatment of trichomonal vaginitis. J Infect Dis. 1994;170:242–6.

    Article  PubMed  CAS  Google Scholar 

  29. Smilack JD, Wilson WR, Cockerill III FR. Tetracyclines, chloramphenicol, erythromycin, clindamycin, and metronidazole. Mayo Clin Proc. 1991;66:1270–80.

    Article  PubMed  CAS  Google Scholar 

  30. Flagyl. Prescribing Information. Chicago, IL: Pfizer Inc., 2004.

    Google Scholar 

  31. Pearlman MD, Yashar C, Ernst S, Solomon W. An incremental dosing protocol for women with severe vaginal trichomoniasis and adverse reaction to metronidazole. Am J Obstet Gynecol. 1996;174:934–6.

    Article  PubMed  CAS  Google Scholar 

  32. Schmid G, Narcisi E, Mosure D, Secor WE, Higgins J, Moreno H. Prevalence of metronidazole-resistant Trichomonas vaginalis in a gynecology clinic. J Reprod Med. 2001;46:545–9.

    PubMed  CAS  Google Scholar 

  33. Pattman RS. Recalcitrant vaginal trichomoniasis. Sex Transm Infect. 1999;75:127–8.

    Article  PubMed  CAS  Google Scholar 

  34. Feola DJ, Thornton AC. Metronidazole-induced pancreatitis in a patient with recurrent vaginal trichomoniasis. Pharmacotherapy. 2002;22:1508–10.

    Article  PubMed  Google Scholar 

  35. Cotch MF, Pastorek II JG, Nugent RP, et al. Trichomonas vaginalis associated with low birth weight and preterm delivery. The Vaginal Infections and Prematurity Study Group. Sex Transm Dis. 1997;24:353–60.

    Article  PubMed  CAS  Google Scholar 

  36. Burtin P, Taddio A, Ariburnu O, Einarson TR, Koren G. Safety of metronidazole in pregnancy: a meta-analysis. Am J Obstet Gynecol. 1995;172:525–9.

    Article  PubMed  CAS  Google Scholar 

  37. Piper JM, Mitchel EF, Ray WA. Prenatal use of metronidazole and birth defects: no association. Obstet Gynecol. 1993;82:348–52.

    PubMed  CAS  Google Scholar 

  38. National Institute of Allergy and Infectious Diseases. Workshop summary: scientific evidence on condom effectiveness for sexually transmitted disease (STD) prevention. Washington, DC: National Institutes of Health, Department of Health Services, 2001. Available from: http://www.niaid.nih.gov/dmid/stds/condomreport.pdf. Accessed Nov. 24, 2006.

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Correspondence to Anne Moore DNP, APN, FAANP .

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Moore, A. (2013). Trichomoniasis. In: Skolnik, N., Clouse, A., Woodward, J. (eds) Sexually Transmitted Diseases. Current Clinical Practice. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-499-9_9

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  • DOI: https://doi.org/10.1007/978-1-62703-499-9_9

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  • Publisher Name: Humana Press, Totowa, NJ

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