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Multimodality MRI-Guided Targeting

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Imaging and Focal Therapy of Early Prostate Cancer

Part of the book series: Current Clinical Urology ((CCU))

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Abstract

The development of new minimally ablative therapies for prostate cancer has led to an increase in the interest for imaging-guided biopsy comparatively to the traditional biopsy technique such as TRUS-guided 12-core systematic biopsy. The strategy of pre-biopsy Mp-MRI and targeted biopsy for prostate cancer management can be effective in detecting a greater proportion of cancers that are clinically significant and in better quality sampling (tumor volume and grade) compared to standard TRUS-guided biopsies. It may also be used as a triage test to rule out cancer and avoid biopsies. Targeting biopsies to an MRI-suspicious area can be carried out in several ways such as free-hand “cognitive” targeted biopsy under TRUS guidance, MRI-directed real-time biopsy (MRI guidance) or real-time virtual navigation system with fusion of the MR images to the ultrasound images, and targeted biopsy under TRUS/MRI fusion guidance.

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Author information

Authors and Affiliations

  1. Department of Urology, University Lille Nord de France, Hospital Huriez, CHRU Lille, 59037, France

    Arnauld Villers M.D.

  2. Department of Urology, Hôpital Claude Huriez, CHRU Lille, Rue Michel Polonovski, Lille, 59000, France

    Adil Ouzzane M.D.

Authors
  1. Arnauld Villers M.D.
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  2. Adil Ouzzane M.D.
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Corresponding author

Correspondence to Arnauld Villers M.D. .

Editor information

Editors and Affiliations

  1. , Department of Surgery, Duke Cancer Institute, Room 1089 Duke South, Durham, 27710, North Carolina, USA

    Thomas J. Polascik

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Villers, A., Ouzzane, A. (2013). Multimodality MRI-Guided Targeting. In: Polascik, T. (eds) Imaging and Focal Therapy of Early Prostate Cancer. Current Clinical Urology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-182-0_10

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  • DOI: https://doi.org/10.1007/978-1-62703-182-0_10

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-181-3

  • Online ISBN: 978-1-62703-182-0

  • eBook Packages: MedicineMedicine (R0)

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