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Cord Blood Banking for Regenerative Therapy

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Book cover Regenerative Therapy Using Blood-Derived Stem Cells

Part of the book series: Stem Cell Biology and Regenerative Medicine ((STEMCELL))

Abstract

The first successful umbilical cord blood (UCB) transplant in 1989 on a patient with Fanconi anemia sparked the creation of cord blood banks worldwide, including more than 100 public banks and nearly 500,000 banked units. Although cord blood units have been historically collected and stored for use in hematopoietic transplantation, there is increasing attention regarding nonhematopoietic cells within cord blood units and their important regenerative functions, making the prospect of using UCB for vascular repair or regenerative therapy most exciting. In this chapter, we provide an outline of various cell types with regenerative function that are present in UCB units and discuss the potential role of using banked cord blood cells for regenerative therapy.

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Author information

Authors and Affiliations

  1. Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada

    Jennifer Klowak & Yuan Chung

  2. Regenerative Medicine Program, Ottawa Hospital Research Institute, Blood and Marrow Transplant Program, Ottawa, ON, Canada

    David S. Allan

  3. Departments of Medicine and Biochemistry, Microbiology & Immunology, University of Ottawa, Ottawa, ON, Canada

    David S. Allan

Authors
  1. Jennifer Klowak
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  2. Yuan Chung
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  3. David S. Allan
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Corresponding author

Correspondence to David S. Allan .

Editor information

Editors and Affiliations

  1. Ottawa Hospital Research Institute, Parkdale Ave 725, Ottawa, K1Y4E9, Ontario, Canada

    David S. Allan

  2. , Center for Medical Research (ZMF), Medical University of Graz, Stiftingtalstraße 24, Graz, A - 8010, Austria

    Dirk Strunk

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© 2012 Springer Science+Business Media, LLC

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Klowak, J., Chung, Y., Allan, D.S. (2012). Cord Blood Banking for Regenerative Therapy. In: Allan, D., Strunk, D. (eds) Regenerative Therapy Using Blood-Derived Stem Cells. Stem Cell Biology and Regenerative Medicine. Humana Press. https://doi.org/10.1007/978-1-61779-471-1_12

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