Abstract
The first successful umbilical cord blood (UCB) transplant in 1989 on a patient with Fanconi anemia sparked the creation of cord blood banks worldwide, including more than 100 public banks and nearly 500,000 banked units. Although cord blood units have been historically collected and stored for use in hematopoietic transplantation, there is increasing attention regarding nonhematopoietic cells within cord blood units and their important regenerative functions, making the prospect of using UCB for vascular repair or regenerative therapy most exciting. In this chapter, we provide an outline of various cell types with regenerative function that are present in UCB units and discuss the potential role of using banked cord blood cells for regenerative therapy.
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Klowak, J., Chung, Y., Allan, D.S. (2012). Cord Blood Banking for Regenerative Therapy. In: Allan, D., Strunk, D. (eds) Regenerative Therapy Using Blood-Derived Stem Cells. Stem Cell Biology and Regenerative Medicine. Humana Press. https://doi.org/10.1007/978-1-61779-471-1_12
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DOI: https://doi.org/10.1007/978-1-61779-471-1_12
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