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Neuroprotection in Parkinson’s Disease

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Abstract

Parkinson’s disease (PD) is a progressive disorder of the CNS characterized by tremor at rest, bradykinesia (slowness of movement), rigidity, and flexed posture. Pathologically, the key deficit has been considered to be loss of pigmented dopamine-producing neurons in the substantia nigra. Although the cause of the disease remains unknown, considerable progress has been made to expand our knowledge of the clinical features, neuropathology, and treatment of the disease since the description of the disease by James Parkinson about 200 years ago.

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Correspondence to Kewal K. Jain .

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Jain, K.K. (2011). Neuroprotection in Parkinson’s Disease. In: The Handbook of Neuroprotection. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-049-2_7

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