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Cancer Stem Cells in Solid Tumors

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Stem Cells & Regenerative Medicine

Part of the book series: Stem Cell Biology and Regenerative Medicine ((STEMCELL))

Abstract

The existence of cancer stem cells continues to be extensively debated among scientists, and given the mounting evidence, it is an area that needs further examination. The possible reason for resistance to current treatment modalities in cancer is that we have yet to discover a method to eradicate cancer stem cells. This chapter describes the theory of cancer stem cells, portrays the role of cancer stem cells in radiation and chemotherapy resistance, and describes methods for their isolation. Finally, it presents current knowledge on cancer stem cells in solid organ tumors and discusses the limitations of current isolation strategies.

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  1. Department of Surgery, Imperial College of London, Hammersmith Campus, Du Cane Road, London, W12 ONN, UK

    Natasa Levicar

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  1. Elodie du Potet
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  2. Lauren Cameron
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  3. Nagy A. Habib
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  4. Natasa Levicar
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Correspondence to Natasa Levicar .

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  1. Gene Expression Systems, Inc., Waltham, Massachusetts, USA

    Krishnarao Appasani

  2. Student Science, Wyllys Ave 45, Middletown, 06459, Connecticut, USA

    Raghu K. Appasani

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© 2011 Springer Science+Business Media, LLC

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du Potet, E., Cameron, L., Habib, N.A., Levicar, N. (2011). Cancer Stem Cells in Solid Tumors. In: Appasani, K., Appasani, R. (eds) Stem Cells & Regenerative Medicine. Stem Cell Biology and Regenerative Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-860-7_4

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