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Congenital Hypothyroidism

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Book cover Pediatric Endocrinology

Part of the book series: Contemporary Endocrinology ((COE))

Abstract

Congenital hypothyroidism remains the leading cause of preventable ­mental impairment worldwide. It is most often caused by iodine deficiency (endemic cretinism) or thyroid dysgenesis but can be caused by any defect in thyroid hormone production, regulation, or action. Because congenital hypothyroidism is common and newborns initially exhibit few specific signs or symptoms of the disorder, most developed countries offer universal newborn thyroid screening. With early identification and treatment of affected newborns, neurologic sequelae are minimized, and development in most adequately treated cases is normal.

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  1. Beth Israel Deaconess Hospital Needham, Harvard Medical School, 148 Chestnut Street, Needham, MA, 02492, USA

    Cecilia A. Larson M.D.

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  1. Cecilia A. Larson M.D.
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  1. School of Medicine, Department of Pediatrics, The Johns Hopkins University, 600 North Wolfe St., Baltimore, 21287, Maryland, USA

    Sally Radovick

  2. , Department of Pediatrics, Children's Hospital of Buffalo, 219 Bryant St., Buffalo, 14222, New York, USA

    Margaret H. MacGillivray

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Larson, C.A. (2013). Congenital Hypothyroidism. In: Radovick, S., MacGillivray, M. (eds) Pediatric Endocrinology. Contemporary Endocrinology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-395-4_15

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