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Amyloid and Related Disorders pp 3–8Cite as

Aspects of the History and Nomenclature of Amyloid and Amyloidosis

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Part of the book series: Current Clinical Pathology ((CCPATH))

Abstract

While the name amyloid has been used for only 150 years, the history of amyloid goes back several 100 years. The modern history may be said to have started with the characterization of the amyloid as cross beta-sheet structured fibrils. The finding that a number of different proteins can make up the fibrils made a strict nomenclature necessary. The principles of this are described in the chapter.

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References

  1. Kyle RA, Bayrd ED. Amyloidosis: review of 236 cases. Medicine. 1975;54:271–99.

    Article  PubMed  CAS  Google Scholar 

  2. Glenner GG. Amyloid deposits and amyloidosis. The β-fibrilloses. N Engl J Med. 1980;302:1283–92 & 1333–43.

    Article  PubMed  CAS  Google Scholar 

  3. Cohen AS. General introduction and a brief history of amyloidosis. In: Marrink J, van Rijswijk MH, editors. amyloidosis. Dordrecht: Martinus Nijhoff Publishers; 1986. p. 3–19.

    Chapter  Google Scholar 

  4. Sipe JD, Cohen AS. Review: history of the amyloid fibril. J Struct Biol. 2000;130:88–98.

    Article  PubMed  CAS  Google Scholar 

  5. Westermark P. Amyloidosis and amyloid proteins: brief history and definitions. In: Sipe JD, editor. Amyloid proteins The beta sheet conformation and disease. Weinheim: Wiley-VCH; 2005. p. 3–27.

    Google Scholar 

  6. Mandema E, Ruinen L, Scholten H, Cohen AS. Amyloidosis. Amsterdam: Excerpta Medica; 1968.

    Google Scholar 

  7. Wegelius O, Pasternack A. Amyloidosis. London: Academic Press; 1976.

    Google Scholar 

  8. Virchow R. Ueber eine im Gehirn und Ruckenmark des Menschen aufgefunde Substanz mit der chemishen Reaction der Cellulose. Virchows Arch Path Anat. 1854;6:135–8.

    Article  Google Scholar 

  9. Friedreich N, Kekulé A. Zur Amyloidfrage. Virchows Arch Pathol Anat. 1859;16:50–65.

    Article  Google Scholar 

  10. Wild C. Ueber eine im Gehirn und Ruckenmark des Menschen aufgefunde Substanz mit der chemishen Reaction der Cellulose. Beitr path Anat. 1886;1:175–200.

    Google Scholar 

  11. Soyka J. Ueber die amyloide Degeneration. Prag med Wschr. 1876;1:165–71.

    Google Scholar 

  12. Lubarsch O. Zur Kenntnis ungewöhnlicher Amyloidablagerungen. Virchows Arch f Path Anat. 1929;271:867–89.

    Article  Google Scholar 

  13. Vossius A. Ueber amyloide Degeneration der Conjunctiva. Beitr path Anat Allg Path. 1889;4:335–60.

    Google Scholar 

  14. Ostertag B. Demonstration einer eigenartigen familiären “Paramyloidose”. Zentralbl Pathol. 1933;56:253–4.

    Google Scholar 

  15. Andrade C. A peculiar form of peripheral neuropathy: familial atypical generalized amylodosis with special involvement of the peripheral nerves. Brain. 1952;75:408–27.

    Article  PubMed  CAS  Google Scholar 

  16. Costa PP, Figueira AS, Bravo FR. Amyloid fibril protein related to prealbumin in familial amyloidotic polyneuropathy. Proc Natl Acad Sci USA. 1978;75:4499–503.

    Article  PubMed  CAS  Google Scholar 

  17. Tawara S, Nakazato M, Kangawa K, Matsuo H, Araki S. Identification of amyloid prealbumin variant in familial amyloidotic polyneuropathy (Japanese type). Biochem Biophys Res Commun. 1983;116:880–8.

    Article  PubMed  CAS  Google Scholar 

  18. Saraiva MJ. Hereditary transthyretin amyloidosis: molecular basis and therapeutical strategies. Expert Rev Mol Med. 2002;4:1–11.

    Article  PubMed  Google Scholar 

  19. Connors LH, Lim A, Prokaeva T, Roskens VA, Costello CE. Tabulation of human transthyretin (TTR) variants, 2003. Amyloid. 2003;10:160–84.

    Article  PubMed  CAS  Google Scholar 

  20. Benson MD, James S, Scott K, Liepnieks JJ, Kluve-Beckerman B. Leucocyte chemotactic factor 2: a novel renal amyloid protein. Kidney Int. 2008;74:218–22.

    Article  PubMed  CAS  Google Scholar 

  21. Cohen AS, Calkins E. Electron microscopic observations on a fibrous component in amyloid of diverse origins. Nature. 1959;183:1202–3.

    Article  PubMed  CAS  Google Scholar 

  22. Eanes ED, Glenner GG. X-ray diffraction studies on amyloid filaments. J Histochem Cytochem. 1968;16:673–7.

    Article  PubMed  CAS  Google Scholar 

  23. Divry P, Florkin M. Sur les propriétées optiques de l’amyloide. C R Soc Biol (Paris). 1927;97:1808–10.

    Google Scholar 

  24. Romhányi G. Uber die submikroskopische Struktur des Amyloid. Schweiz Z Pathol (Pathol Microbiol). 1949;12:253–62.

    Google Scholar 

  25. Benditt EP, Eriksen N. Chemical classes of amyloid substance. Am J Pathol. 1971;65:231–52.

    PubMed  CAS  Google Scholar 

  26. Benditt EP, Eriksen N, Hermodson MA, Ericsson LH. The major proteins of human and monkey amyloid substance: common properties including unusual N-terminal amino acid sequences. FEBS Lett. 1971;19:169–73.

    Article  PubMed  CAS  Google Scholar 

  27. Glenner GG, Terry W, Harada M, Isersky C, Page D. Amyloid fibril proteins: proof of homology with immunoglobulin light chains by sequence analysis. Science. 1971;172:1150–1.

    Article  PubMed  CAS  Google Scholar 

  28. Sletten K, Westermark P, Natvig JB. Characterization of amyloid fibril proteins from medullary carcinoma of the thyroid. J Exp Med. 1976;143:993–8.

    Article  PubMed  CAS  Google Scholar 

  29. Bennhold H. Eine specifische Amyloidfärbung mit Kongorot. Munch Med Wochenschr. 1922;69:1537–8.

    Google Scholar 

  30. Steensma DP. “Congo” red out of Africa? Arch Path Lab Med. 2001;125:250–2.

    PubMed  CAS  Google Scholar 

  31. Bennhold H. Über die Asscheidung intravenös einverbleibten Kongorotes bei den verschiedensten Erkrankungen insbesondere bei Amyloidosis. Deutsch Arch f klin Med. 1923;142:32–46.

    Google Scholar 

  32. Morgan WKC, Mules JE. The intravenous congo red test: a description of some unrecognized fallacies with suggested improvements. Am J Med Sci. 1960;239:61–70.

    Article  Google Scholar 

  33. Ouchi E, Nomura N, Watabe S, Seiji K, Sato J, Gonai T, Miura K, Yamagata S. Clinical significance of congo red test. Tohoku J Exp Med. 1976;118(suppl):191–8.

    Article  PubMed  Google Scholar 

  34. Patra S, Jhala CI, Patra BS. Intravenous congo red test in pulmonary tuberculosis for detection of amyloidosis, its value and limitations. J Assoc Physicians India. 1976;24:553–7.

    PubMed  CAS  Google Scholar 

  35. Afkhami A, Moosavi A. Adsorptive removal of congo red, a carcinogenic textile dye, from aqueous solutions by maghemite nanoparticles. J Hazard Mater. 2010;174:398–403.

    Article  PubMed  CAS  Google Scholar 

  36. Griesbach H. Weitere Untersuchungen über Azofarbstoffe behufs Tinction menchlischer und thierischer Gewebe. Zeitschr Wissenschaft MikroskopMicroskop Tech. 1886;3:358–85.

    Google Scholar 

  37. Symmers WSC. Primary amyloidosis: a review. J Clin Pathol. 1956;9:187–211.

    Article  PubMed  CAS  Google Scholar 

  38. Gafni J, Sohar E. Rectal biopsy for the diagnosis of amyloidosis. Am J Med Sci. 1960;240:332–6.

    Article  PubMed  CAS  Google Scholar 

  39. Editorial. (1963) Clinical diagnosis of amyloidosis. J Am Med Assoc 183, 1104.

    Google Scholar 

  40. Westermark P, Stenkvist B. A new method for the diagnosis of systemic amyloidosis. Arch Intern Med. 1973;132:522–3.

    Article  PubMed  CAS  Google Scholar 

  41. Hawkins PN, Richardson S, MacSweeney JE, King AD, Vigushin DM, Lavender JP, Pepys MB. Scintigraphic quantification and serial monitoring of human visceral amyloid deposits provide evidence for turnover and regression. Quart J Med. 1993;86:365–74.

    PubMed  CAS  Google Scholar 

  42. Gellerstedt N. Die elektive, insuläre (Para-)Amyloidose der Bauchspeicheldrüse. zugleich en Beitrag zur Kenntnis der “senilen Amyloidose”. Beitr Path Anat. 1938;101:1–13.

    Google Scholar 

  43. Sipe JD, Benson MD, Buxbaum JN, Ikeda S, Merlini G, Saraiva MJ, Westermark P. Amyloid fibril protein nomenclature: 2010 recommendations of the nomenclature committee of the International Society of amyloidosis. Amyloid. 2010;17:101–4.

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

Supported by the Swedish Research Council.

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Authors and Affiliations

  1. Rudbeck Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, SE 751 85, Uppsala, Sweden

    Per Westermark M.D., Ph.D.

Authors
  1. Per Westermark M.D., Ph.D.
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Correspondence to Per Westermark M.D., Ph.D. .

Editor information

Editors and Affiliations

  1. Bldg#110, Rm#2242, Department of Pathology, Loyola University Medical Center, S. First Avenue 2160, Maywood, 60153, Illinois, USA

    Maria M. Picken MD, PhD, FASN

  2. , Department of Laboratory Medicine and Pa, Mayo Clinic, First Street SW 200, Rochester, 55905, USA

    Ahmet Dogan, M.D., Ph.D.

  3. , Department of Renal Pathology, Bostwick Laboratories, Lake Ellenor Dr. 8001, Orlando, 32809, Florida, USA

    Guillermo A. Herrera, M.D.

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Westermark, P. (2012). Aspects of the History and Nomenclature of Amyloid and Amyloidosis. In: Picken MD, PhD, FASN, M., Dogan, M.D., Ph.D., A., Herrera, M.D., G. (eds) Amyloid and Related Disorders. Current Clinical Pathology. Humana Press. https://doi.org/10.1007/978-1-60761-389-3_1

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  • DOI: https://doi.org/10.1007/978-1-60761-389-3_1

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60761-388-6

  • Online ISBN: 978-1-60761-389-3

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