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Gout

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Book cover Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease

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Key Points

  • Gout is caused by a deposition of monosodium urate within joints and soft tissues due to supersaturation of body fluids.

  • Gout has been increasing in incidence due to increasing risk factors such as obesity, increased alcohol consumption, hypertension, and high purine diet.

  • Gout develops in four stages: asymptomatic hyperuricemia, acute gouty arthritis, the intercritical period, and chronic tophaceous gout. The first metatarsophalangeal joint is often affected (podagra).

  • Gout is treated in three phases: treatment of the acute attack, prevention of future acute and rebound attacks, and hypouricemic therapy.

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Authors and Affiliations

  1. Department of Pathology, Dermatopathology & Dermatology, Stanford University School of Medicine, Stanford Hospital and Clinics, 300 Pasteur Drive Room H2110, Stanford, CA, 94305, USA

    Uma Sundram

Authors
  1. Uma Sundram
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Correspondence to Uma Sundram .

Editor information

Editors and Affiliations

  1. College of Medicine, Dept. Pathology, University of Arkansas, W. Markham St. 4301, Little Rock, 72205, Arkansas, USA

    Bruce R. Smoller

  2. Dipto. Scienze Endocrinologiche e, Mediche, Università di Genova, Viale Francesco Gambaro 19/6, Genova, 16146, Italy

    Franco Rongioletti

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Sundram, U. (2010). Gout. In: Smoller, B., Rongioletti, F. (eds) Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-60761-181-3_7

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  • DOI: https://doi.org/10.1007/978-1-60761-181-3_7

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-60761-180-6

  • Online ISBN: 978-1-60761-181-3

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