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Colloid Milium

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Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease

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Key Points

  • Colloid milium is a rare, degenerative skin condition characterized by deposition of amorphous hyaline-like material in the dermis.

  • Colloid milium and colloid degeneration include at least four distinct clinicopathological conditions: classic adult-type colloid milium, juvenile colloid milium, nodular ­colloid degeneration (paracolloid), and pigmented colloid milium (hydroquinone related).

  • There are usually no systemic implications, with the exception of a rare ligneous conjunctivitis or periodontitis in the juvenile type.

  • Special stains, immunohistochemical studies, and electron microscopy have allowed the distinction from similar conditions such as amyloidosis.

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References

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Authors and Affiliations

  1. Department of Endocrinological and Medical Sciences (DISEM) Section of Dermatology and Department of Pathology, University of Genova, Genova, Italy

    Franco Rongioletti

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  1. Franco Rongioletti
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Correspondence to Franco Rongioletti .

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Editors and Affiliations

  1. College of Medicine, Dept. Pathology, University of Arkansas, W. Markham St. 4301, Little Rock, 72205, Arkansas, USA

    Bruce R. Smoller

  2. Dipto. Scienze Endocrinologiche e, Mediche, Università di Genova, Viale Francesco Gambaro 19/6, Genova, 16146, Italy

    Franco Rongioletti

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Rongioletti, F. (2010). Colloid Milium. In: Smoller, B., Rongioletti, F. (eds) Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-60761-181-3_20

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  • DOI: https://doi.org/10.1007/978-1-60761-181-3_20

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-60761-180-6

  • Online ISBN: 978-1-60761-181-3

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