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Upper Aerodigestive Tract Carcinoma Surveillance Counterpoint: Canada

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Part of the book series: Current Clinical Oncology ((CCO))

Abstract

The number of new mucosal cancers of the upper aerodigestive tract in Canada each year exceeds 4,500 cases, with about 700 deaths [1] (2.8 % of new cancer cases and 2.3 % of cancer-related deaths). The estimated age standardized incidence for oral cancer by Province ranges from 9 to 14 per 100,000 population for males and 4 to 6 per 100,000 for females. Larynx is the single most common site. The incidence across provinces varies from 3 to 8 per 100,000. There appears to be a relatively higher incidence of these cancers in the Atlantic Provinces, Quebec, and Manitoba. Higher historical smoking rates have been documented for Quebec and the Atlantic Provinces. The annual incidence of laryngeal cancer is declining for both males and females by 3.6–3.4 % annually, and the mortality rate among males is decreasing [1].

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References

  1. Canadian Cancer Statistics. 2008. http://www.cancer.ca. Accessed 18 Nov 2008.

  2. Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A (Eds). AJCC Cancer Staging Handbook 7th ed. USA: Springer 2010

    Google Scholar 

  3. NCCN clinical practice guidelines in oncology. 2008. http://www.nccn.org. Accessed 18 Nov 2008

  4. Taneja C, Allen H, Koness RJ, Radie-Keane K, Wanebo HJ. Changing patterns in failure of head and neck cancer. Arch Otolaryngol Head Neck Surg. 2002;128:324–7.

    PubMed  Google Scholar 

  5. Carvalho AL, Magrin J, Kowalski LP. Sites of recurrence in oral and oropharyngeal cancers according to the treatment approach. Oral Dis. 2003;9:112–8.

    Article  PubMed  CAS  Google Scholar 

  6. Grau JJ, Cuchi A, Traserra J, Fírvida JL, Arias C, Blanch JL, et al. Follow-up study in head and neck cancer: cure rate according to tumor location and stage. Oncology. 1997;54(1):38–42.

    Article  PubMed  CAS  Google Scholar 

  7. Cooney TR, Poulsen MG. Is routine follow-up useful after combined-modality therapy for advanced head and neck cancer? Arch Otolaryngol Head Neck Surg. 1999;125:379–82.

    PubMed  CAS  Google Scholar 

  8. Haas I, Hauser U, Ganzer U. The dilemma of follow-up in head and neck cancer patients. Eur Arch Otorhinolaryngol. 2001;258:177–83.

    Article  PubMed  CAS  Google Scholar 

  9. Spector JG, Sessions DG, Haughey BH, Chao KS, Simpson J, El Mofty S, et al. Delayed regional metastases, distant metastases, and second primary malignancies in squamous cell carcinomas of the larynx and hypopharynx. The Laryngoscope 2001;111(6): 1079–87.

    Article  PubMed  CAS  Google Scholar 

  10. Anneroth G, Hansen LS, Silverman Jr S. Malignancy grading in oral squamous cell carcinoma. I. Squamous cell carcinoma of the tongue and floor of mouth: histologic grading in the clinical evaluation. J Oral Pathol. 1986;15(3):162–8.

    Article  PubMed  CAS  Google Scholar 

  11. Bryne M, Koppang HS, Lilleng R, Stene T, Bang G, Dabelsteen E. New malignancy grading is a better prognostic indicator than Broders’ grading in oral squamous cell carcinomas. J Oral Pathol Med. 1989;18(8):432–7.

    Article  PubMed  CAS  Google Scholar 

  12. Brandwein-Gensler M, Teixeira MS, Lewis CM, Lee B, Rolnitzky L, Hille JJ, et al. Oral squamous cell carcinoma: histologic risk assessment, but not margin status, is strongly predictive of local disease-free and overall survival. Am J Surg Pathol. 2005;29(2):167–78.

    Article  PubMed  Google Scholar 

  13. Spiro RH, Huvos AG, Wong GY, Spiro JD, Gnecco CA, Strong EW. Predictive value of tumor thickness in squamous carcinoma confined to the tongue and floor of the mouth. Am J Surg. 1986;152(4):345–50.

    Article  PubMed  CAS  Google Scholar 

  14. Po WY, Lam KY, Lam LK, Ho CM, Wong A, Chow TL, et al. Prognostic factors of clinically stage I and II oral tongue carcinoma-A comparative study of stage, thickness, shape, growth pattern, invasive front malignancy grading, Martinez-Gimeno score, and pathologic features. Head and Neck. 2002;24(6):513–20.

    Article  Google Scholar 

  15. Sutton DN, Brown JS, Rogers SN, Vaughan ED, Woolgar JA. The prognostic implications of the surgical margin in oral squamous cell carcinoma. Int J Oral Maxillofac Surg. 2003;32(1): 30–4.

    Article  PubMed  CAS  Google Scholar 

  16. Binahmed A, Nason RW, Abdoh AA. The clinical significance of the positive surgical margin in oral cancer. Oral Oncol. 2007;43(8): 780–4.

    Article  PubMed  Google Scholar 

  17. Kowalski LP. Results of salvage treatment of the neck in patients with oral cancer. Arch Otolaryngol Head Neck Surg. 2002;128:58–62.

    PubMed  Google Scholar 

  18. Schwartz GJ, Mehta RH, Wenig BL, Shaligram C, Portugal LG. Salvage treatment for recurrent squamous cell carcinoma of the oral cavity. Head and Neck. 2000;22(1):34–41.

    Article  PubMed  CAS  Google Scholar 

  19. Boysen M, Lovdal O, Tausjo J, Winther F. The value of follow-up in patients treated for squamous cell carcinoma of the head and neck. Eur J Cancer. 1992;28(2–3):426–30.

    Article  PubMed  CAS  Google Scholar 

  20. Merkx MA, van Gulick JJ, Marres HA, Kaanders JH, Bruaset I, Verbeek A, et al. Effectiveness of routine follow-up of patients treated for T1-2N0 oral squamous cell carcinomas of the floor of mouth and tongue. Head and Neck. 2006;28(1):1–7.

    Article  Google Scholar 

  21. Ritoe SC, Bergman H, Krabbe PFM, Kaanders JH, van den Hoogen FJ, Verbeek AL, et al. Cancer recurrence after total laryngectomy: treatment options, survival, and complications. Head and Neck. 2006;28(5):383–388.

    Article  PubMed  Google Scholar 

  22. Dhooge IJ, De Vos M, Van Cauwenberge PB. Multiple primary malignant tumors in patients with head and neck cancer: results of a prospective study and future perspectives. Laryngoscope. 1998;108(2):250–6.

    Article  PubMed  CAS  Google Scholar 

  23. Schwartz LH, Ozsahin M, Zhang GN, Touboul E, De Vataire F, Andolenko P, et al. Synchronous and metachronous head and neck carcinomas. Cancer. 1994;74(7):1933–8.

    Article  PubMed  CAS  Google Scholar 

  24. Vikram B. Changing patterns of failure in advanced head and neck cancer. Arch Otolaryngol Head Neck Surg. 1984;110(9):564–5.

    Article  CAS  Google Scholar 

  25. Lippman SM, Hong WK. Second malignant tumors in head and neck squamous cell carcinoma: the overshadowing threat for patients with early-stage disease. Int J Radiat Oncol Biol Phys. 1989;17(3):691–4.

    Article  PubMed  CAS  Google Scholar 

  26. Licciardello JT, Spitz MR, Hong WK. Multiple primary cancer in patients with cancer of the head and neck: second cancer of the head and neck, esophagus, and lung. Int J Radiat Oncol Biol Phys. 1989;17(3):467–76.

    Article  PubMed  CAS  Google Scholar 

  27. Gleich LL, Ryzenman J, Gluckman JL, et al. Recurrent advanced (T3 or T4) head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2004;130:35–8.

    Article  PubMed  Google Scholar 

  28. Wong LY, Wei WI, Lam LK, Yuen APW. Salvage of recurrent head and neck squamous cell carcinoma after primary curative surgery. Head Neck. 2003;25(11):953–9.

    Article  PubMed  Google Scholar 

  29. Goodwin Jr WJ. Salvage surgery for patients with recurrent squamous cell carcinoma of the upper aerodigestive tract: when do the ends justify the means? Laryngoscope. 2000;110 Suppl 93:1–18.

    Article  PubMed  Google Scholar 

  30. Stoeckli SJ, Pawlik AB, Lipp M, Huber A, Schmid S. Salvage surgery after failure of nonsurgical therapy for carcinoma of the larynx and hypopharynx. Arch Otolaryngol Head Neck Surg. 2000;126: 1473–1477.

    PubMed  CAS  Google Scholar 

  31. Ganly I, Patel SG, Matsuo J, Singh B, Kraus DH, Boyle JO, et al. Results of surgical salvage after failure of definitive radiation therapy for early-stage squamous cell carcinoma of the glottic larynx. Arch Otolaryngol Head Neck Surg. 2006;132:59–66.

    Article  PubMed  Google Scholar 

  32. Arnold DJ, Goodwin WJ, Weed DT, Civantos FJ. Treatment of recurrent and advanced stage squamous cell carcinoma of the head and neck. Semin Radiat Oncol. 2004;14(2):190–5.

    Article  PubMed  Google Scholar 

  33. Calhoun KH, Fulmer P, Weiss R, Hokanson JA. Distant metastases from head and neck squamous cell carcinomas. Laryngoscope. 1994;104(10):1199–205.

    Article  PubMed  CAS  Google Scholar 

  34. Geurts TW, Balm AJM, van Velthuysen MLF, van Tinteren H, Burgers JA, van Zandwijk N, et al. Survival after surgical resection of pulmonary metastases and second primary squamous cell lung carcinomas in head and neck cancer. Head Neck. 2009;31(2): 220–6.

    Google Scholar 

  35. Douglas WG, Rigual NR, Loree TR, Wiseman SM, Al-Rawi S, Hicks WL Jr. Current concepts in the management of a second malignancy of the lung in patients with head and neck cancer. Curr Opin Otolaryngol Head Neck Surg. 2003 Apr;11(2):85–8. Review.

    Google Scholar 

  36. Nason RW, Sako K, Beecroft WA, Razack MS, Bakamjian VY, Shedd DP. Surgical management of squamous cell carcinoma of the floor of the mouth. Am J Surg. 1989;158:292–6.

    Article  PubMed  CAS  Google Scholar 

  37. Lee WR, Mendenhall WM, Parsons JT, Million RR, Cassisi NJ, Stringer SPl. Carcinoma of the tonsillar region: a multivariate analysis of 243 patients treated with radical radiotherapy. Head and Neck. 1993;15:283–8.

    Article  PubMed  CAS  Google Scholar 

  38. Rodgers LW, Stringer SP, Mendenhall WM, Parsons JT, Cassisi NJ, Million RR. Management of squamous cell carcinoma of the floor of mouth. Head and Neck. 1993;15:16–9.

    Article  PubMed  Google Scholar 

  39. Sessions DG, Spector GJ, Lenox J, Haughey B, Chao C, Marks Jl. Analysis of treatment results for oral tongue cancer. Laryngoscope. 2002;112(4):616–25.

    Article  PubMed  Google Scholar 

  40. Mendenhall WM, Parsons JT, Stringer SP, Cassisi NJ. Management of Tis, T1, and T2 squamous cell carcinoma of the glottic larynx. Am J Otolaryngol. 1994;15(4):250–7.

    Article  PubMed  CAS  Google Scholar 

  41. Spector GJ, Sessions DG, Chao KSC, Haughey BH, Hanson JM, Simpson JR, et al. Stage I (T1 N0 M0) squamous cell carcinoma of the laryngeal glottis: therapeutic results and voice preservation. Head and Neck. 1999;21(8):707–17.

    Article  PubMed  CAS  Google Scholar 

  42. Gleich LL, Collins CM, Gartside PS, Gluckman JL, Barrett WL, Wilson KM, et al. Therapeutic decision making in stage III and IV head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2003;129(1):26–35.

    Article  PubMed  Google Scholar 

  43. Spector GJ, Sessions DG, Lenox J, Newland D, Simpson J, Haughey BH. Management of stage IV glottic carcinoma: therapeutic outcomes. Laryngoscope. 2004;114(8):1438–46.

    Article  PubMed  Google Scholar 

  44. Sessions DG, Lenox J, Spector GJ, Chao C, Chaudry OA. Analysis of treatment results for base of tongue cancer. Laryngoscope. 2003;113(7):1252–61.

    Article  PubMed  Google Scholar 

  45. Marchant FE, Lowry LD, Moffitt JJ, Sabbagh R. Current national trends in the posttreatment follow-up of patients with squamous cell carcinoma of the head and neck. Am J Otolaryngol. 1993;14(2):88–93.

    Article  PubMed  CAS  Google Scholar 

  46. Clinical practice guidelines for the diagnosis and management of cancer of the head and neck. The American Society for Head and Neck Surgery and American Head and Neck Society 1995, http://www.ahns.info/clinicalresources/.

  47. De Visscher AV, Manni JJ. Routine long-term follow-up in patients treated with curative intent for squamous cell carcinoma of the larynx, pharynx, and oral cavity. Does it make sense? Arch Otolaryngol Head Neck Surg. 1994;120(9):934–9.

    Article  PubMed  Google Scholar 

  48. Ritoe SC, Verbeek ALM, Krabbe PFM, Kaanders JH, van den Hoogen FJ, Marres HA. Screening for local and regional cancer recurrence in patients curatively treated for laryngeal cancer: definition of a high-risk group and estimation of the lead time. Head and Neck. 2007;29(5):431–8.

    Article  PubMed  Google Scholar 

  49. Ritoe SC, Krabbe PF, Kaanders JH, van den Hoogen FJ, Verbeek AL, Marres HA. Value of routine follow-up for patients cured of laryngeal carcinoma. Cancer. 2004;101(6):1382–9.

    Article  PubMed  Google Scholar 

  50. Ritoe SC, Krabbe PF, Jansen MM, Festen J, Joosten FB, Kaanders JH, et al. Screening for second primary lung cancer after treatment of laryngeal cancer. Laryngoscope. 2002;112(11):2002–8.

    Article  PubMed  Google Scholar 

  51. Merkx MA, Boustahji AH, Kaanders JH, Joosten F, Marres HA, Bruaset I, et al. A half-yearly chest radiograph for early detection of lung cancer following oral cancer. Int J Oral Maxillofac Surg. 2002;31(4):378–82.

    Article  Google Scholar 

  52. Shah SI, Applebaum EL. Lung cancer after head and neck cancer: role of chest radiography. Laryngoscope. 2000;110(12):2033–6.

    Article  PubMed  CAS  Google Scholar 

  53. Van der Molen L, van Rossum M, Burkhead L, Smeele LE, Hilgers FJ. Functional outcomes and rehabilitation strategies in patients treated with chemoradiotherapy for advanced head and neck cancer: a systematic review. Eur Arch Otorhinolaryngol. 2009;266(6): 889–900. Epub 2008 Sep 30.

    Google Scholar 

  54. Geurts TW, Ackerstaff AH, Van Zandwijk, Hart AA, Hilgers FJ, Balm AJ. The psychological impact of annual chest X-Ray follow-up in head and neck cancer. Acta Otolaryngol. 2006;126(12):1315–20.

    Article  PubMed  CAS  Google Scholar 

  55. Van den Brekel MW, Castelijns JA, Snow GB. Diagnostic evaluation of the neck. Otolaryngol Clin North Am. 1998;31(4):601–20.

    Article  PubMed  Google Scholar 

  56. Nieuwenhuis EJ, Castelijns JA, Pijpers R, van den Brekel MW, Brakenhoff RH, van der Waal I, et al. Wait-and-see policy for the N0 neck in early-stage oral and oropharyngeal squamous cell ­carcinoma using ultrasonography-guided cytology: is there a role for identification of the sentinel node? Head and Neck. 2002:24(3): 282–9.

    Article  PubMed  Google Scholar 

  57. Goerres GW, Schmid DT, Bandhauer F, Huguenin PU, von Schulthess GK, Schmid S, et al. Positron emission tomography in the early follow-up of advanced head and neck cancer. Arch Otolaryngol Head Neck Surg. 2004;130:105–9.

    Article  PubMed  Google Scholar 

  58. Isles MG, McConkey C, Mehanna HM. A systematic review and meta-analysis of the role of positron emission tomography in the follow up of head and neck squamous cell carcinoma following radiotherapy or chemotherapy. Clin Otolaryngol. 2008;33:210–22.

    Article  PubMed  CAS  Google Scholar 

  59. Cheng AC, Schmidt BL. Management of the N0 neck in oral squamous cell carcinoma. Oral Maxillofac Surg Clin N Am. 2008;40(3):477–97.

    Article  Google Scholar 

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Correspondence to Richard W. Nason .

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Nason, R.W., Butler, J.B. (2013). Upper Aerodigestive Tract Carcinoma Surveillance Counterpoint: Canada. In: Johnson, F., et al. Patient Surveillance After Cancer Treatment. Current Clinical Oncology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60327-969-7_8

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  • DOI: https://doi.org/10.1007/978-1-60327-969-7_8

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