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Clinical Management of Renal Tumors pp 9–42Cite as

Imaging of Renal Cell Carcinoma

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Abstract

Imaging of renal neoplasms is performed with computed tomography, magnetic resonance, and ultrasound to detect disease, characterize lesions, stage primary renal neoplasms, and provide surgical planning information. Imaging is also used to distinguish between benign and malignant disease and between surgical and nonsurgical disease. Computed tomography (CT) and magnetic resonance (MR) exams of renal cell carcinoma should be designed to maximize identification of prognostic factors as well as staging features: size, extension outside the renal capsule and fascia, lymphadenopathy, renal vein invasion, and metastatic disease.

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References

  1. Jemal A, Murray T, Samuels A, et al. Cancer statistics. CA Cancer J Clin 2003;53:5–26.

    Article  PubMed  Google Scholar 

  2. Jayson M, Sanders H. Increased incidence of serendipitously discovered renal cell carcinoma. Urology 1998;51:203–205.

    Article  PubMed  CAS  Google Scholar 

  3. Luciani LG, Cestari R, Tallarigo C. Incidental renal cell carcinoma-age and stage characterization and clinical implications: study of 1092 patients (1982–1997). Urology 2000;56:58–62.

    Article  PubMed  CAS  Google Scholar 

  4. Smith SJ, Bosniak MA, Megibow AJ, Hulnick Dh, Horri SC, Ragavendra BN. Renal cell carcinoma: earlier discovery and increased detection. Radiology 1989;170:699–703.

    PubMed  CAS  Google Scholar 

  5. Breatheau D, Lechevallier E, Eghazarian C, et al. Prognostic significance of incidental renal cell carcinoma. Eur Urol 1995;27:319–323.

    Google Scholar 

  6. Mejean A, Oudard S, Thiounn N. Prognostic factors of renal cell carcinoma. J Urol 2003;169:821–827.

    Article  PubMed  Google Scholar 

  7. Fuhrman SA, Lasky LC, Limas C. Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol 1982;6:655–663.

    PubMed  CAS  Google Scholar 

  8. Bostwick DG, Murphy GP. Diagnosis and prognosis of renal cell carcinoma: highlights from an international consensus workshop. Semin Urol Oncol 1998;16:46–52.

    PubMed  CAS  Google Scholar 

  9. Heidenreich A, Ravery V. Preoperative imaging in renal cell cancer. World J Urol 2004;22:307–315.

    Article  PubMed  Google Scholar 

  10. Wolf JS Jr. Evaluation and management of solid and cystic renal masses. J Urol 1998;159:1120–1133.

    Article  PubMed  Google Scholar 

  11. Zagoria RJ, Wolfman NT, Karstaedt N, Hinn GC, Dyer RB, Chen YM. CT features of renal cell carcinoma with emphasis on relation to tumor size. Invest Radiol 1990;25:261.

    PubMed  CAS  Google Scholar 

  12. Yamashita Y, Watanabe O, Miyazaki T, et al. Cystic renal cell carcinoma; imaging findings with pathologic correlation. Acta Radiol 1994;35:19–24.

    Article  PubMed  CAS  Google Scholar 

  13. Curry NS. Atypical cystic renal masses. Abdom Imaging 1998;23:230–236.

    Article  PubMed  CAS  Google Scholar 

  14. Eble JN, Bonsib SM. Extensively cystic renal neoplasms: cystic nephroma, cystic partially differentiated nephroblastoma, multilocular cystic renal cell carcinoma, and cystic hamartoma of the renal pelvis. Semin Diagn Pathol 1998;15:2–20.

    PubMed  CAS  Google Scholar 

  15. Bosniak MA. The current radiological approach to renal cysts. Radiology 1986;158:1–10.

    PubMed  CAS  Google Scholar 

  16. Bosniak MA. Difficulties in classifying cystic lesions of the kidney. Urol Radiol 1991;13:91–93.

    Article  PubMed  CAS  Google Scholar 

  17. Israel GM, Bosniak MA. Calcification in cystic renal masses: is it important in diagnosis? Radiology 2003;226:47–52.

    Article  PubMed  Google Scholar 

  18. Israel GM, Hindman N, Bosniak MA. Evaluation of cystic renal masses: comparison of CT and MR using the Bosniak classification system. Radiology 2004;231:365–371.

    Article  PubMed  Google Scholar 

  19. Siegel CL, Fisher AJ, Bennett HF. Interobserver variability in determining enhancement of renal masses on helical CT. AJR 1999;172:1207–1212.

    PubMed  CAS  Google Scholar 

  20. Wilson TE, Doelle EA, Cohan RH, et al. Cystic renal masses: a reevaluation of the usefulness of the Bosniak classification system. Acad Radiol 1996;3:564–570.

    Article  PubMed  CAS  Google Scholar 

  21. Harishinghani MG, Maher MM, Gervais DA, et al. Incidence of malignancy in complex cystic renal masses (Bosniak III): should biopsy precede surgery. AJR 2003;180:755–758.

    Google Scholar 

  22. Pickhardt PJ, Lonergan GJ, Davis CJ, et al. Infiltrative renal lesions: radiologic-pathologic correlation. Radiographics 2000;20:215–243.

    PubMed  CAS  Google Scholar 

  23. Cohan RH, Dunnick NR, Leder RA. Computed tomography of renal lymphoma. J Comput Assist Tomogr 1990;14:933–938.

    Article  PubMed  CAS  Google Scholar 

  24. Araki T. Leukemic involvement of the kidney in children: CT features. J Comput Assist Tomogr 1982;6:781–784.

    Article  PubMed  CAS  Google Scholar 

  25. Mitnick JS, Bosniak MA, Rothberg M. Metastatic neoplasm to the kidney studied by computed tomography and sonography. J Comput Assist Tomogr 1985;9:43–49.

    Article  PubMed  CAS  Google Scholar 

  26. Gattuso P, Ramzy I, Truong LD, et al. Utilization of fine-needle aspiration in the diagnosis of metastatic tumors to the kidney. Diagn Cytopathol 1999;21:35–38.

    Article  PubMed  CAS  Google Scholar 

  27. Honda H, Onitsuka H, Naitou S, et al. Renal arteriovenous malformations: CT features. J Comput Assist Tomogr 1991;15:261–264.

    Article  PubMed  CAS  Google Scholar 

  28. King BF, Hattery RR. Case of the day. Ultrasound. Congenital cirsoid renal arteriovenous malformation (AVM) involving the lower pole of the right kidney. Radiographics 1990;10:1101–1104

    PubMed  CAS  Google Scholar 

  29. Vasavada SP, Manion S, Flanigan RC, et al. Renal arteriovenous malformations masquerading as renal cell carcinoma. Urology 1995;46:716–721.

    Article  PubMed  CAS  Google Scholar 

  30. Morton MJ, Charboneau JW. Arteriovenous fistula after biopsy of renal transplant: detection and monitoring with color flow and duplex ultrasonography. Mayo Clin Proc 1989;64:531–534.

    PubMed  CAS  Google Scholar 

  31. Middleton WD, Kellman GM, Melson GL, et al. Postbiopsy renal transplant arteriovenous fistulas: color Doppler US characteristics. Radiology 1989;171:253–257.

    PubMed  CAS  Google Scholar 

  32. Israel GM, Bosniak MA. Renal imaging for diagnosis and staging of renal cell carcinoma. Urol Clin North Am 2003;30:499–514.

    Article  PubMed  Google Scholar 

  33. Helenon o, Correas JM, Balleyquier C, et al. Ultrasound of renal tumors. Eur Radiol 2001;11:1890–1901.

    Article  PubMed  CAS  Google Scholar 

  34. Mihara S, Kuroda K, Yoshioka R, et al. Early detection of renal cell carcinoma by ultrasonographic screening—based on 13 years screening in exam. Ultrasound Med Biol 1999;25:1033–1039.

    Article  PubMed  CAS  Google Scholar 

  35. Tosaka A, Ohya K, Yamada K, et al. Incidence and properties of renal masses and asymptomatic renal cell carcinoma detected by abdominal ultrasonography. J Urol 1990;144:1097–1099.

    PubMed  CAS  Google Scholar 

  36. Kitamura H, Fujimoto H, Tobisu K, et al. Dynamic computed Tomography and color Doppler ultrasound of renal parenchymal neoplasms: correlation with histopathological findings. Jpn J Cln Oncol 2004;34:78–81.

    Article  Google Scholar 

  37. Park BK, Kim SH, Choi HJ. Characterization of renal cell carcinoma using agent detection imaging: comparison with gray-scale ultrasound. Korean J Radiol 2005;6:173–178.

    Article  PubMed  Google Scholar 

  38. Jinzaki M, Tanimoto A, Mukai M, et al. Double-phase helical CT of small renal parenchymal neoplasms: correlation with pathological findings and tumor angiogenesis J Comput Assist Tomogr 2000;24:835–842.

    Article  PubMed  CAS  Google Scholar 

  39. Herts BR, Coll DM, Novick AC, et al. Enhancement characteristics of papillary renal neoplasms revealed on triphasic helical CT of the kidneys AJR 2002;178:367–372.

    PubMed  Google Scholar 

  40. Kopka L, Fischer U, Zoeller G, et al. Dual-phase helical CT of the kidney: value of the corticomedullary and nephrographic phase for evaluation of renal lesions and preoperative staging of renal cell carcinoma. AJR 1997;169:1573–1578.

    PubMed  CAS  Google Scholar 

  41. Kauczor HU, Schwickert HC, Schweden F, et al. Bolus-enhanced renal spiral CT: techniques, diagnostic value and drawbacks. Eur J Radiol 1994;18:153–157.

    Article  PubMed  CAS  Google Scholar 

  42. Garant M, Bonaldi VM, Taourel P, et al. Enhancement patterns of renal masses during multiphase helical CT acquisitions. Abdom Imaging 1998;23:431–436.

    Article  PubMed  CAS  Google Scholar 

  43. Cohan RH, Sherman LS, Korobkin M, et al. Renal masses: assessment of corticomedullary-phase and nephrographic-phase CT scans. Radiology 1995;196:445–451.

    PubMed  CAS  Google Scholar 

  44. Birnbaum BA, Jacobs JE, Ramchandani P. Multiphasic renal CT: comparison of renal mass enhancement during the corticomedullary and nephrographic phases. Radiology 1996;200:753–758.

    PubMed  CAS  Google Scholar 

  45. Szolar DH, Kammerhuber F, Altziebler S, et al. Multiphasic helical CT of the kidney: increased conspicuity for detection and characterization of small (<3-cm) renal masses. Radiology 1997;202:211–217.

    PubMed  CAS  Google Scholar 

  46. Herts BR, Coll DM, Lieber ML, et al. Triphasic helical CT of the kidneys: contribution of vascular phase scanning in patients before urologic surgery. AJR 1999;1273-1277.

    Google Scholar 

  47. Herts BR, Einstein DM, Paushter DM. Spiral CT of the abdomen: artifacts and potential pitfalls. AJR 1993;161:1185–1190.

    PubMed  CAS  Google Scholar 

  48. Macari M, Bosniak MA. Delayed CT to evaluate renal masses incidentally discovered at contrastenhanced CT: demonstration of vascularity with deenhancement. Radiology 1999;213:674–680.

    PubMed  CAS  Google Scholar 

  49. Voci SL, Gottlieb RH, Fultz PJ, et al. Delayed computed tomographic characterization of renal masses: a preliminary experience. Abdom Imaging 2000;25:317–321.

    Article  PubMed  CAS  Google Scholar 

  50. Chung EP, Herts BR, Linnell G, et al. Analysis of changes in attenuation of proven renal cysts on different scanning phases of triphasic MDCT. AJR 2004;182:405–410.

    PubMed  Google Scholar 

  51. Coulam CH, Sheafor DH, Leder RA, et al. Evaluation of pseudoenhancement of renal cysts during contrast-enhanced CT. AJR 2000;174:493–498.

    PubMed  CAS  Google Scholar 

  52. Maki DD, Birnbaum BA, Chakraborty DP, et al. Renal cyst pseudoenhancement: beam-hardening effects on CT numbers. Radiology 1999;213:468–472.

    PubMed  CAS  Google Scholar 

  53. Coll DM, Uzzo RG, Herts BR, et al. 3—dimensional volume rendered computerized Tomography for preoperative evaluation and intraoperative treatment of patients undergoing nephron sparing surgery. J Urol 1999;161:1097–1102.

    Article  PubMed  CAS  Google Scholar 

  54. Coll DM, Herts BR, Davros WJ, et al. Preoperative use of 3D volume rendering to demonstrate renal tumors and renal anatomy. RadioGraphics 2000;20:431–438.

    PubMed  CAS  Google Scholar 

  55. Choyke PL, Walther MM, Wagner JR, et al. Renal cancer: preoperative evaluation with dual-phase three-dimensional MR angiography. Radiology 1997;205:767–771.

    PubMed  CAS  Google Scholar 

  56. Catalano C, Fraioli F, Laghi A, et al. High-resolution multidetector CT in the preoperative evaluation of patients with renal cell carcinoma. AJR 2003;180:1271–1277.

    PubMed  CAS  Google Scholar 

  57. Sheth S, Scatarige JC, Horton KM, et al. Current concepts in the diagnosis and management of renal cell carcinoma: role of multidetector CT and three-dimensional CT. RadioGraphics 2001;21: S237–254.

    Google Scholar 

  58. Wunderlich H, Reichelt O, Schubert R, et al. Preoperative simulation of partial nephrectomy with three-dimensional computed tomography. BJU Int 2000;86:777–781.

    Article  PubMed  CAS  Google Scholar 

  59. Rofsky NM, Weinreb JC, Bosniak MA, et al. Renal lesion characterization with gadoliniumenhanced MR imaging: efficacy and safety in patients with renal insufficiency. Radiology 1991;180:85–89.

    PubMed  CAS  Google Scholar 

  60. Kramer LA. Magnetic resonance imaging of renal masses. World J Urol 1998;16:22–28.

    Article  PubMed  CAS  Google Scholar 

  61. Narumi Y, Hricak H, Presti JC Jr, et al. MR imaging of renal cell carcinoma. Abdom Imaging 1997;22:216–225.

    Article  PubMed  CAS  Google Scholar 

  62. Ho VB, Allen SF, Hood MN, et al. Renal masses: quantitative assessment of enhancement with dynamic MR imaging. Radiology 2002;224:695–700.

    Article  PubMed  Google Scholar 

  63. Hecht EM, Israel GM, Krinsky GA, et al. Renal masses: quantitative analysis of enhancement with signal intensity measurements versus qualitative analysis of enhancement with image subtraction for diagnosing malignancy at MR imaging. Radiology 2004;232:373–378.

    Article  PubMed  Google Scholar 

  64. Ho VB, Choyke PL. MR evaluation of solid renal masses. MRI Clin North Am 2004;12:413–427.

    Article  Google Scholar 

  65. Walter C, Kruessell M, Gindele A, et al. Imaging of renal lesions: evaluation of fast MRI and helical CT. Br J Radiol 2003;76:696–703.

    Article  PubMed  CAS  Google Scholar 

  66. Semelka RC, Shoenut JP, Magro CM, et al. Renal cancer staging: comparison of contrast-enhanced CT and Gadolinium-enhanced fat-suppressed spin-echo and gradient-echo MR imaging. J MRI 1993;3:597–602.

    CAS  Google Scholar 

  67. Hallscheidt PJ, Bock M, Riedasch G, et al. Diagnostic accuracy of staging renal cell carcinoma using multidetector-row computed tomography and magnetic resonance imaging. J Comput Assist Tomogr 2004;28:333–339.

    Article  PubMed  Google Scholar 

  68. Pretorius ES, Wickstrom L, Siegelman ES. MR imaging of renal neoplasms. MRI Clin North Am 2000;8:813–836.

    CAS  Google Scholar 

  69. Weiss LM, Gelb AB, Medeiros LJ. Adult renal epithelial neoplasms. Am J Clin Pathol 1995;103:624–635.

    PubMed  CAS  Google Scholar 

  70. Bostwick DG, Eble JN. Diagnosis and classification of renal cell carcinoma. Urol Clin North Am 1999;26:627–635.

    Article  PubMed  CAS  Google Scholar 

  71. Zisman A, Chao DH, Pantuck AJ, et al. Unclassified renal cell carcinoma: clinical features and prognostic impact of a new histological subytype. J Urol 2002;168:950–955.

    Article  PubMed  Google Scholar 

  72. Kim JK, Kim TK, Ahn HJ, Kim CS, Kim KR, Cho KS. Differentiation of subtypes of renal cell carcinoma on helical CT scans. AJR 2002;178:1499–1506.

    PubMed  Google Scholar 

  73. Sheir KZ, El-Azab M, Mosbah A, et al. Differentiation of renal cell carcinoma subtypes by multislice computerized tomography. J Urol 2005;174:451–455.

    Article  PubMed  Google Scholar 

  74. Shinmoto H, Yuasa Y, Tanimoto A, et al. Small renal cell carcinoma: MRI with pathological correlation. J MRI 1998;8:690–694.

    CAS  Google Scholar 

  75. Uzzo RG, Cherullo EE, Myles J, et al. Renal cell carcinoma invading the urinary collecting system: implications for staging. J Urol 2002;167:2392–2396.

    Article  PubMed  Google Scholar 

  76. Delahunt B, Eble JN. Papillary renal cell carcinoma: a clinicopathologic and immunohistochemical study of 105 cases. Mod Pathol 1997;10:537–544.

    PubMed  CAS  Google Scholar 

  77. Lager DJ, Huston BJ, Timmerman TG, Bonsib SM. Papillary renal tumors. Cancer 1995;76:669.

    Article  PubMed  CAS  Google Scholar 

  78. Onishi T, Ohishi Y, Goto H, et al. Papillary renal cell carcinoma: clinicopathological characteristics and evaluation of prognosis in 42 patients. BJU Int 1999;83:937–943.

    Article  PubMed  CAS  Google Scholar 

  79. Ruppert-Kohlmayr AJ, Uggowitzer M, Meissnitzer T, et al. Differentiation of renal clear cell carcinoma and renal papillary carcinoma using quantitative CT enhancement parameters. AJR 2004;183:1387–1391.

    PubMed  Google Scholar 

  80. Mejean A, Hopirtean V, Bazin JP, et al. Prognostic factors for the survival of patients with papillary renal cell carcinoma: meaning of histologic typing and multifocality. J Urol 2003;170:764–767.

    Article  PubMed  Google Scholar 

  81. Megumi Y, Nishimura K. Chromophobe renal cell carcinoma. Urol Int 1998;61:172–174.

    Article  PubMed  CAS  Google Scholar 

  82. Kondo T, Nakazawa H, Sakai F, et al. Spoke-wheel-like enhancement as an important imaging finding of chromophobe cell renal carcinoma: a retrospective analysis on computed tomography and magnetic resonance imaging studies. Int J Urol 2004;11:817–824.

    Article  PubMed  Google Scholar 

  83. Srigley JR, Eble JN. Collecting duct carcinoma of kidney. Semin Diagn Pathol 1998;15:54–67.

    PubMed  CAS  Google Scholar 

  84. Fukuya T, Honda H, Goto K, et al. Computed tomographic findings of Bellini duct carcinoma of the kidney. J Comput Assist Tomogr 1996;20:399–403.

    Article  PubMed  CAS  Google Scholar 

  85. Gurocak S, Sozen S, Akyurek N, et al. Cortically located collecting duct carcinoma. Urology 2005;65:1226.

    Article  PubMed  Google Scholar 

  86. Pickhardt PJ, Siegel CL, McLarney JK. Collecting duct carcinoma of the kidney: are imaging findings suggestive of the diagnosis? AJR 2001;176:627–633.

    PubMed  CAS  Google Scholar 

  87. Pickhardt PJ. Collecting duct carcinoma arising in a solitary kidney: imaging findings. Clin Imaging 1999;23:115–118.

    Article  PubMed  CAS  Google Scholar 

  88. Mian BM, Bhadkamkar NJ, Slaton JW, et al. Prognostic factors and survival of patients with sarcomatoid renal cell carcinoma. Urology 2002;167:65–70.

    Article  Google Scholar 

  89. Staelens L, Van Poppel H, Vanuytsel L, et al. Sarcomatoid renal cell carcinoma: case report and review of the literature. Acta Urol Belg 1997;65:39–42.

    PubMed  CAS  Google Scholar 

  90. Tanabe A, Naruse M, Ogawa T, et al. Dynamic computed tomography is useful in the differential diagnosis of juxtaglomerular cell tumor and renal cell carcinoma. Hypertens Res 2001;24:331–336.

    Article  PubMed  CAS  Google Scholar 

  91. Davidson AJ, Hayes WJ, Hartman DS, et al. Renal oncocytoma and carcinoma: failure of differentiation with CT. Radiology 1993;186:693–696.

    PubMed  CAS  Google Scholar 

  92. Wiatrowska BA, Zakowski MF. Fine-needle aspiration biopsy of chromophobe renal cell carcinoma and oncocytoma: comparison of cytomorphologic features. Cancer 1999;87:161–167.

    Article  PubMed  CAS  Google Scholar 

  93. Liu J, Fanning CV. Can renal oncocytomas be distinguished from renal cell carcinoma on fine-needle aspiration specimens? A study of conventional smears in conjunction with ancillary studies. Cancer 2001;93:390–397.

    Article  PubMed  CAS  Google Scholar 

  94. Bracken RB, Chica G, Johnson DE, et al. Secondary renal neoplasms: an autopsy study. South Med J 1979;72:806–807.

    PubMed  CAS  Google Scholar 

  95. Wood BJ, Khan MA, McGovern F, et al. Imaging guided biopsy of renal masses: indications, accuracy and impact on clinical management. J Urol 1999;161:1470–1474.

    Article  PubMed  CAS  Google Scholar 

  96. Sheeran SR, Sussman SK. Renal lymphoma: spectrum of CT findings and potential mimics. AJR 1998;171:1067–1072.

    PubMed  CAS  Google Scholar 

  97. Grignon DJ, Eble JN. Papillary and metanephric adenomas of the kidney. Semin Diagn Pathol 1998;15:41–53.

    PubMed  CAS  Google Scholar 

  98. Kim JK, Park SY, Shon JH, et al. Angiomyolipoma with minimal fat: differentiation from renal cell carcinoma at biphasic helical CT. Radiology 2004;230:677–684.

    Article  PubMed  Google Scholar 

  99. Schuster TG, Ferguson MR, Baker DE, et al. Papillary renal cell carcinoma containing fat without calcification mimicking angiomyolipoma on CT. AJR 2004;183:1402–1404.

    PubMed  Google Scholar 

  100. Hammadeh MY, Thomas K, Philp T, et al. Renal cell carcinoma containing fat mimicking angiomyolipoma: demonstration with CT scan and histopathology. Eur Radiol 1998;8:228–229.

    Article  PubMed  CAS  Google Scholar 

  101. Siegel CL, Middleton WD, Teefey SA, et al. Angiomyolipoma and renal cell carcinoma: US differentiation. Radiology 1996;198:789–793.

    PubMed  CAS  Google Scholar 

  102. Roy C, Tuchman C, Linder V, et al. Renal cell carcinoma with a fatty component mimicking angiomyolipoma at CT. Br J Radiol 1998;71:977–979.

    PubMed  CAS  Google Scholar 

  103. Radin DR, Chandrasoma P. CT demonstration of fat density in renal cell carcinoma. Acta Radiol 1992;33:365–367.

    Article  PubMed  CAS  Google Scholar 

  104. Wang LJ, Wong YC, Chen CJ, et al. Computerized Tomography characteristics that differentiate angiomyolipomas from liposarcomas in the perinephric space. J Urol 2002;167:490–493.

    Article  PubMed  Google Scholar 

  105. Israel GM, Bosniak MA, Slywotzky CM, et al. CT differentiation of large exophytic angiomyolipomas and perirenal liposarcomas. AJR 2002;179:769–773.

    PubMed  Google Scholar 

  106. Robson CJ, Churchill BM, Anderson W, et al. The results of radical nephrectomy for renal cell carcinoma. J Urol 1969;101:297.

    PubMed  CAS  Google Scholar 

  107. Fleming ID, et al. editors. American Joint Committee on Cancer (AJCC). AJCC Manual for Staging of Cancer, 5th ed. Philadelphia: Lippincott-Raven, 1997:231–234.

    Google Scholar 

  108. Gettman MT, Blute ML, Spotts B, et al. Pathologic staging of renal cell carcinoma. Cancer 2001;91:354–361.

    Article  PubMed  CAS  Google Scholar 

  109. Guinan P, Sobin LH, Algaba F, et al. TNM staging of renal cell carcinoma. Cancer 1997; 80:992–993.

    Article  PubMed  CAS  Google Scholar 

  110. Sobin LH, Wittekind CH, eds. International Union Against Cancer (UICC). TNM Classification of Malignant Tumors, 5th ed. New York: UICC, 1997:180–182.

    Google Scholar 

  111. Tsui KH, Shvarts O, Smith R, et al. Prognostic indicators for renal cell carcinoma: a multivariate analysis of 643 patients using the revised 1997 TNM staging system. J Urol 2000;163:1090–1095.

    Article  PubMed  CAS  Google Scholar 

  112. Javidan J, Strciker HJ, Tamboli P, et al. Prognostic significance of the 1997 TNM classification of renal cell carcinoma. J Urol 2000;162:1277–1281.

    Article  Google Scholar 

  113. Dinney CP, Awad SA, Gajewski J, et al. Analysis of imaging modalities, staging systems, and prognostic indicators for renal cell carcinoma. Urology 1992;39:122–129.

    Article  PubMed  CAS  Google Scholar 

  114. Constantinides C, Recker F, Bruehlmann W, et al. Accuracy of magnetic resonance imaging compared to computerized tomography and selective renal Angiography in preoperatively staging renal cell carcinoma. Urol Int 1991;47:181–185.

    PubMed  CAS  Google Scholar 

  115. Bechtold RE, Zagoria RJ. Imaging approach to staging of renal cell carcinoma. Urol Clin North Am 1997; 24:507–522.

    Article  PubMed  CAS  Google Scholar 

  116. Johnson CD, Dunnick NR, Cohan RH, et al. Renal adenocarcinoma: CT staging of 100 tumors. AJR 1987;148:59–63.

    PubMed  CAS  Google Scholar 

  117. Cronan JJ, Zeman RK, Rosenfeld AT. Comparison of computerized tomography, ultrasound and angiography in staging renal cell carcinoma. J Urol 1982;127:712–714.

    PubMed  CAS  Google Scholar 

  118. Prati GF, Saggin P, Boschiero L, et al. Small renal-cell carcinomas: clinical and imaging features. Urol Int 1993;51:19–22.

    Article  PubMed  CAS  Google Scholar 

  119. Hricak H, Thoeni RF, Carroll PR, et al. Detection and staging of renal neoplasms: a reassessment of MR imaging. Radiology 1988;166:643–649.

    PubMed  CAS  Google Scholar 

  120. Zagoria RJ, Bechtold RE, Dyer RB. Staging of renal adenocarcinoma: role of various imaging procedures. AJR 1995;164:363–370.

    PubMed  CAS  Google Scholar 

  121. Roberts WW, Bhayani J, Allaf ME, et al. Pathological stage does not alter the prognosis for renal lesions determined to be stage T1 by computerized tomography. Urology 2005;173:713–715.

    Article  Google Scholar 

  122. Ozen H, Colowick A, Freiha FS. Incidentally discovered solid renal masses: what are they? Br J Urol 1993;72:274–276.

    PubMed  CAS  Google Scholar 

  123. Siow WY, Yip SK, Ng LG, et al. Renal cell carcinoma: incidental detection and pathological staging. J R Coll Surg Edinb 2000;45:291–295.

    PubMed  CAS  Google Scholar 

  124. Thompson RH, Leibovich BC, Cheville JC, et al. Is renal sinus fat invasion the same as perinephric fat invasion for a renal cell carcinoma? J Urol 2005;174:1218–1221.

    Article  PubMed  Google Scholar 

  125. Irani J, Humbert M, Lecocq B, et al. Renal tumor size: comparison between computed tomography and surgical measurements. Eur Urol 2001;39:300–303.

    Article  PubMed  CAS  Google Scholar 

  126. Yaycioglu O, Rutman MP, Balasubramaniam M, et al. Clinical and pathologic tumor size in renal cell carcinoma; difference, correlation, and analysis of influencing factors. Urology 2002;60:33–38.

    Article  PubMed  Google Scholar 

  127. Herr HW, Lee CT, Sharma S, et al. Radiographic versus pathologic size of renal tumors: implications for partial nephrectomy. Urology 2001;58:157–160.

    Article  PubMed  CAS  Google Scholar 

  128. Khaitan A, Gupta NP, Hemal AK, et al. Is there a need for pelvic CT scan in cases of renal cell carcinoma? Int Urol Nephrol 2002;33:13–15.

    Article  PubMed  Google Scholar 

  129. Fielding JR, Aliabadi N, Renshaw AA, et al. Staging of 119 patients with renal cell carcinoma: the yield and cost-effectiveness of pelvic CT. AJR 1999;172:1721–1723.

    Google Scholar 

  130. Lim DJ, Carter F. Computerized tomography in the preoperative staging for pulmonary metastases in patients with renal cell carcinoma, J Urol 1993;150:1112–1114.

    PubMed  CAS  Google Scholar 

  131. Tsui KH, Shvarts O, Barbaric Z, et al. Is adrenalectomy a necessary component of radical nephrectomy? UCLA experience with 511 radical nephrectomies. J Urol 2000;163:437–441.

    Article  PubMed  CAS  Google Scholar 

  132. Tsui KH, Shvarts O, Smith RB, Figlin R, DeKernion JB, Belldegrun A. Renal cell carcinoma: prognostic significance of incidentally detected tumors. J Urology 2000;163:426–430.

    Article  CAS  Google Scholar 

  133. Sawai Y, Kinochi T, Mano M, et al. Ipsilateral adrenal involvement from renal cell carcinoma: retrospective study of the predictive value of computed tomography. Urology 2002;59:28–31.

    Article  PubMed  Google Scholar 

  134. Gill IS, McClennan BL, Kerbi K, et al. Adrenal involvement from renal cell carcinoma: predictive value of computerized tomography. J Urol 1994;154:1082–1085.

    Google Scholar 

  135. Hamrahian AH, Ioachimescu AG, Remer EM, et al. Clinical utility of noncontrast computed tomography attenuation value (Hounsfield units) to differentiate adrenal adenomas/hyperplasias from nonadenomas: Cleveland Clinic Experience. J Clin Endocr Metab 2005;90:871–877.

    Article  PubMed  CAS  Google Scholar 

  136. Israel GM, Korobkin M, Wang C, et al. Comparison of unenhanced CT and chemical shift MRI in evaluating lipid-rich adrenal adenomas. AJR 2004;183:215–219.

    PubMed  Google Scholar 

  137. Hatcher PA, Anderson EE, Paulson DF, et al. Surgical management and prognosis of renal cell carcinoma invading the vena cava. J Urol 1991;145:20–24.

    PubMed  CAS  Google Scholar 

  138. Oto A, Herts BR, Remer EM, Novick AC. Inferior vena cava tumor thrombus in renal cell carcinoma: staging by MR imaging and impact on surgical treatment. AJR 1998;171:1619–1624.

    PubMed  CAS  Google Scholar 

  139. Gupta NP, Ansari MD, Khaitan A, et al. Impact of imaging and thrombus level in management of renal cell carcinoma extending to veins. Urol Int 2004;72:129–134.

    Article  PubMed  Google Scholar 

  140. Glazer A, Novick AC. Preoperative transesophageal echocardiography for assessment of venal caval tumor thrombi: a comparative study with venacavography and magnetic resonance imaging. Urology 1997;49:32–34.

    Article  PubMed  CAS  Google Scholar 

  141. Lawrentschuk N, Gani J, Riordan R, et al. Multidetector computed tomography vs. magnetic resonance imaging for defining the upper limit of tumor thrombus in renal cell carcinoma: a study and review. BJU Int 2005;96:291–295.

    Article  PubMed  Google Scholar 

  142. Kallman DA, King BF, Hattery RR, et al. Renal vein and inferior vena cava tumor thrombus in renal cell carcinoma: CT, US, MRI and venacavography. J Comput Assist Tomogr 1992;16:240–247.

    Article  PubMed  CAS  Google Scholar 

  143. Goldfarb DA, Novick AC, Lorig R, et al. Magnetic resonance imaging for assessment of vena cava tumor thrombi: a comparative study with venacavography and computerized tomography scanning. J Urol 1990;144:1100–1103.

    PubMed  CAS  Google Scholar 

  144. Hockley NM, Foster RS, Bihrle R, et al. Use of magnetic resonance imaging to determine surgical approach to renal cell carcinoma with vena caval extension. Urology 1990;36:55–60.

    Article  PubMed  CAS  Google Scholar 

  145. Gohji K, Yamashita C, Ueno K, et al. Preoperative computerized Tomography detection of extensive invasion of the inferior vena cava by renal cell carcinoma: possible indication for resection with partial cardiopulmonary bypass and patch grafting. J Urol 1997;152:1993–1996.

    Google Scholar 

  146. Motzer RJ, Bander NH, Nanus DM. Medical progress: renal cell carcinoma. N Engl J Med 1996;335:865.

    Article  PubMed  CAS  Google Scholar 

  147. Ghavamian R, Klein KA, Stephens DH, et al. Renal cell carcinoma metastatic to the pancreas: clinical and radiographic features. Mayo Clin Proc 2000;75:581–585.

    Article  PubMed  CAS  Google Scholar 

  148. Ng CS, Loyer EM, Iyer RB, et al. Metastases to the pancreas from renal cell carcinoma: findings on three-phase contrast-enhanced helical CT. AJR 1999;172:1555–1559.

    PubMed  CAS  Google Scholar 

  149. Tartar VM, Heiken JP, McClennan BL. Renal cell carcinoma presenting with diffuse peritoneal metastases: CT findings. J Comput Assist Tomogr 1991;15:450–453.

    Article  PubMed  CAS  Google Scholar 

  150. Birnbaum BA, Bosniak MA, Krinsky GA, Cheng D, Waisman J, Ambrosino MM. Renal cell carcinoma: correlation of CT findings with nuclear morphologic grading in 100 tumors. Abdom Imaging 1994;19:262–266.

    Article  PubMed  CAS  Google Scholar 

  151. Frank I, Blute ML, Cheville, et al. Solid renal tumors: an analysis of pathological features related to tumor size. J Urol 2003;170:2217–2220.

    Article  PubMed  Google Scholar 

  152. Kelley CM, Cohen MB, Raab SS. Utility of fine-needle aspiration biopsy in solid renal masses. Diagn Cytopathol 1996;14:14–19.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, Cleveland Clinic Foundation, Cleveland, OH

    Brian R. Herts MD

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  1. Brian R. Herts MD
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  1. Taussig Cancer Center, Cleveland Clinic Foundation, Cleveland, OH

    Ronald M. Bukowski MD

  2. Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH

    Andrew C. Novick MD

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© 2008 Humana Press Inc., Totowa, NJ

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Herts, B.R. (2008). Imaging of Renal Cell Carcinoma. In: Bukowski, R.M., Novick, A.C. (eds) Clinical Management of Renal Tumors. Humana Press. https://doi.org/10.1007/978-1-60327-149-3_2

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  • DOI: https://doi.org/10.1007/978-1-60327-149-3_2

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