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Controversies in Treating Diabetes pp 11–32Cite as

Islet Cell Transplantation

How Effective Is It?

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Part of the book series: Contemporary Endocrinology ((COE))

Summary

Islet cell transplantation as a treatment for diabetes has shown great promise, but has significant limitations. Since early animal studies in rats demonstrated its ability to restore euglycemia, islet transplantation has not proven to be a durable or practical therapy for type 1 diabetes. Here we review some of the history, technique, clinical outcomes, and potential alternatives of islet transplantation.

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Authors
  1. Eric H. Liu MD
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  2. David M. Harlan MD
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Editors and Affiliations

  1. Division of Endocrinology, Diabetes, and Bone Disease, Department of Medicine, Mount Sinai School of Medicine, New York, NY

    Derek LeRoith MD PhD

  2. Diabetes Research Institute Department of Medicine, Eastern Virginia Medical School The Leonard Strelitz Diabetes Institutes, Norfolk, VA

    Aaron I. Vinik MD PhD FCP FACP

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© 2008 Humana Press

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Liu, E.H., Harlan, D.M. (2008). Islet Cell Transplantation. In: LeRoith, D., Vinik, A.I. (eds) Controversies in Treating Diabetes. Contemporary Endocrinology. Humana Press. https://doi.org/10.1007/978-1-59745-572-5_2

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