Summary
During the past decade, there has been a resurgence in prostatitis research, most notably focused on chronic prostatitis/chronic pelvic pain syndrome. This work included epidemiological studies, evaluation of diagnostic tests, studies of the impact on quality of life and medical costs, pathogenic mechanisms, biomarkers, as well as randomized clinical trials. Despite this effort our understanding of this burdensome and enigmatic condition remains incomplete and management of patients challenging. The etiology of prostatitis/chronic pelvic pain syndrome is not known, risk factors have not been well described, the pathogenic mechanism(s) are obscure, and optimal treatment strategies have not yet been identified. If advances are to be made in the coming years, then the greatest payoff may come from a concerted effort to identify the cause(s) and risk factors for this condition and to develop and validate accurate phenotypes of those with the syndrome. With this knowledge, rationale selection of potential therapeutic agents may be possible to evaluate in well-designed randomized clinical trials.
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Kusek, J.W., Nyberg, L.M. (2008). Strategies for Increasing the Understanding of Chronic Prostatitis/Chronic Pelvic Pain Syndrome. In: Shoskes, D.A. (eds) Chronic Prostatitis/Chronic Pelvic Pain Syndrome. Current Clinical Urology. Humana Press. https://doi.org/10.1007/978-1-59745-472-8_18
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