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Garlic

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Part of the book series: Forensic Science and Medicine ((FSM))

Abstract

Garlic possesses a variety of beneficial pharmacological properties affecting most notably the cardiovascular system (lipid management, decreased blood pressure, platelet inhibition, and decreased fibrinolytic activity), and the immune system as an antineoplastic and immunostimulant agent. It is also a potent antioxidant. Although its effects are modest in some clinical applications, its inherent safety and culinary benefits usually support its use when a mild clinical effect is acceptable. There is the potential for interactions with drugs possessing antiplatelet and anticoagulant effects. Additionally, potential induction of various cytochrome P450 enzymes warrants closer monitoring of drugs metabolized through this pathway when garlic is concomitantly administered.

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Authors
  1. Leslie Helou
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  2. Ila M. Harris
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Editors and Affiliations

  1. Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN

    Timothy S. Tracy PhD

  2. SafetyCall International, PLLC, Clinical Services, Bloomington, MN

    Richard L. Kingston PharmD

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Helou, L., Harris, I.M. (2007). Garlic. In: Tracy, T.S., Kingston, R.L. (eds) Herbal Products. Forensic Science and Medicine. Humana Press. https://doi.org/10.1007/978-1-59745-383-7_8

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