Skip to main content

Pulmonary Rehabilitation

  • Chapter
  • First Online:
Book cover COPD

Part of the book series: Respiratory Medicine ((RM))

  • 5293 Accesses

Key Points

Pulmonary Rehabilitation is an evidence-based, multidisciplinary, and comprehensive intervention for patients with chronic respiratory diseases.

Consequences of COPD include:

  • Respiratory limitation

  • Reripheral muscle dysfunction

  • Respiratory muscle dysfunction

  • Cardiac abnormality

  • Nutritional abnormality

  • Skeletal abnormality

  • Psychosocial issue

Recent studies have unraveled mechanistic reasons why pulmonary rehabilitation works.

The components of pulmonary rehabilitation include:

  • Assessment/re-assessment

  • Exercise training

  • Education and self-management strategies

  • Nutritional intervention

  • Psychological and social consideration

Pulmonary rehabilitation has emerged as an evidence-based science showing its effectiveness across multiple outcome areas. However, pulmonary rehabilitation does not improve forced expiratory volume at 1 s (FEV1).

Pulmonary rehabilitation has now become one of the standard therapies for chronic obstructive pulmonary disease.

The major goals of pulmonary rehabilitation are:

  • To reduce burden of symptoms such as dyspnoea and fatigue

  • To improve functional status

  • To increase participation in physical and social activities

  • To improve health related quality of life

  • To reduce health care utilization

The following are general criteria for pulmonary rehabilitation referral:

  • Severe dyspnoea and/or fatigue

  • Decreased exercise ability

  • Interference with performing physical activities of daily living

  • Impaired health status

  • Decreased occupational performance

  • Nutritional depletion

  • Frequent respiratory exacerbations

  • Increased medical resource consumption

Pulmonary rehabilitation should be administered throughout the course of COPD, be an integral part of COPD therapy, and complement pharmacological intervention for COPD.

Pulmonary rehabilitation is still under-utilized due to combination of ­under-awareness of its effectiveness by health care providers, unavailability of programs in some area, and insufficient third-party reimbursement.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Haas A, Cardon H (1969) Rehabilitation in chronic obstructive lung disease: a 5-year study of 252 male patients. Med Clin North Am 53:593–606

    CAS  PubMed  Google Scholar 

  2. Global Initiative for Chronic Obstructive Pulmonary Disease Workshop Report. http://www.goldcopd.com

  3. ATS-ERS Statement on the Diagnosis and Treatment of COPD www.thoracic.org

  4. Nici L, Donner C, ZuWallack R, Wouters E et al (2006) The ATS/ERS statement on pulmonary rehabilitation. Am J Respir Crit Care Med 173:1390–1414

    PubMed  Google Scholar 

  5. ACCP-AACVPR Pulmonary Rehabilitation Guidelines Panel (1997) Pulmonary rehabilitation: joint ACCP/AACVPR evidence based guidelines. Chest 112:1363–1396

    Google Scholar 

  6. Decramer M et al (2005) Systemic effects of COPD. Respir Med 99(Suppl B):S3–10

    PubMed  Google Scholar 

  7. O’Donnell DE (2001) Ventilatory limitations in chronic obstructive pulmonary disease. Med Sci Sports Exerc 33(7 Suppl):S647–55

    PubMed  Google Scholar 

  8. Rodrigues F (2004) Limiting factors of exercise capacity in patients with COPD. Rev Port Pneumol 10(1):9–61

    PubMed  Google Scholar 

  9. Puente-Maestu L et al (2005) Dyspnea, ventilatory pattern, and changes in dynamic hyperinflation related to the intensity of constant work rate exercise in COPD. Chest 128(2):651–6

    PubMed  Google Scholar 

  10. Bianchi R et al (2004) Chest wall kinematics and breathlessness during pursed-lip breathing in patients with COPD. Chest 125(2):459–65

    PubMed  Google Scholar 

  11. Kobayashi S et al (1996) Relationship between breathlessness and hypoxic and hypercapnic ventilatory response in patients with COPD. Eur Respir J 9(11):2340–5

    CAS  PubMed  Google Scholar 

  12. Somfay A et al (2002) Effect of hyperoxia on gas exchange and lactate kinetics following exercise onset in nonhypoxemic COPD patients. Chest 121(2):393–400

    PubMed  Google Scholar 

  13. Bee D, Howard P (1993) The carotid body: a review of its anatomy, physiology and clinical importance. Monaldi Arch Chest Dis 48(1):48–53

    CAS  PubMed  Google Scholar 

  14. Mador MJ, Bozkanat E (2001) Skeletal muscle dysfunction in chronic obstructive pulmonary disease. Respir Res 2(4):216–24

    CAS  PubMed  Google Scholar 

  15. Maltais F et al (2000) Oxidative enzyme activities of the vastus lateralis muscle and the functional status in patients with COPD. Thorax 55(10):848–53

    CAS  PubMed  Google Scholar 

  16. Franssen FM et al (2005) Limb muscle dysfunction in COPD: effects of muscle wasting and exercise training. Med Sci Sports Exerc 37(1):2–9

    PubMed  Google Scholar 

  17. Schonhofer B et al (1997) Evaluation of a movement detector to measure daily activity in patients with chronic lung disease. Eur Respir J 10(12):2814–9

    CAS  PubMed  Google Scholar 

  18. Bernard S et al (1998) Peripheral muscle weakness in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 158(2):629–34

    CAS  PubMed  Google Scholar 

  19. Troosters T, Gosselink R, Decramer M (2001) Exercise training in COPD: how to distinguish responders from nonresponders. J Cardiopulm Rehabil 21(1):10–7

    CAS  PubMed  Google Scholar 

  20. Maltais F et al (1999) Altered expression of myosin heavy chain in the vastus lateralis muscle in patients with COPD. Eur Respir J 13(4):850–4

    CAS  PubMed  Google Scholar 

  21. Schols AM et al (1996) Evidence for a relation between metabolic derangements and increased levels of inflammatory mediators in a subgroup of patients with chronic obstructive pulmonary disease. Thorax 51(8):819–24

    CAS  PubMed  Google Scholar 

  22. Spruit MA et al (2003) Muscle force during an acute exacerbation in hospitalised patients with COPD and its relationship with CXCL8 and IGF-I. Thorax 58(9):752–6

    CAS  PubMed  Google Scholar 

  23. Decramer M et al (1994) Corticosteroids contribute to muscle weakness in chronic airflow obstruction. Am J Respir Crit Care Med 150(1):11–6

    CAS  PubMed  Google Scholar 

  24. Rahman I, Skwarska E, MacNee W (1997) Attenuation of oxidant/antioxidant imbalance during treatment of exacerbations of chronic obstructive pulmonary disease. Thorax 52(6):565–8

    CAS  PubMed  Google Scholar 

  25. Levine S et al (2002) Bioenergetic adaptation of individual human diaphragmatic myofibers to severe COPD. J Appl Physiol 92(3):1205–13

    PubMed  Google Scholar 

  26. Berger HJ et al (1979) 1979 Memorial Award Paper. Comparison of exercise right ventricular performance in chronic obstructive pulmonary disease and coronary artery disease: noninvasive assessment by quantitative radionuclide angiocardiography. Invest Radiol 14(5):342–53

    CAS  PubMed  Google Scholar 

  27. Faisy C et al (2000) Bioelectrical impedance analysis in estimating nutritional status and outcome of patients with chronic obstructive pulmonary disease and acute respiratory failure. Intensive Care Med 26(5):518–25

    CAS  PubMed  Google Scholar 

  28. Vermeeren MA et al (2006) Prevalence of nutritional depletion in a large out-patient population of patients with COPD. Respir Med 100(8):1349–55

    CAS  PubMed  Google Scholar 

  29. Schols A (2003) Nutritional modulation as part of the integrated management of chronic obstructive pulmonary disease. Proc Nutr Soc 62(4):783–91

    CAS  PubMed  Google Scholar 

  30. Jorgensen NR et al (2007) The prevalence of osteoporosis in patients with chronic obstructive pulmonary disease – a cross sectional study. Respir Med 101(1):177–85

    CAS  PubMed  Google Scholar 

  31. Guell R et al (2006) Impact of pulmonary rehabilitation on psychosocial morbidity in patients with severe COPD. Chest 129(4):899–904

    PubMed  Google Scholar 

  32. Light RW et al (1985) Prevalence of depression and anxiety in patients with COPD. Relationship to functional capacity. Chest 87(1):35–8

    CAS  PubMed  Google Scholar 

  33. Kayahan B et al (2006) Psychological outcomes of an outpatient pulmonary rehabilitation program in patients with chronic obstructive pulmonary disease. Respir Med 100(6):1050–7

    PubMed  Google Scholar 

  34. Emery CF et al (1991) Psychological outcomes of a pulmonary rehabilitation program. Chest 100(3):613–7

    CAS  PubMed  Google Scholar 

  35. Nici L, ZuWallack R, Wouters E, Donner (2006) On pulmonary rehabilitation and the flight of the bumblebee. Eur Respir J 28:461–462

    CAS  PubMed  Google Scholar 

  36. American Association of Cardiovascular and Pulmonary Rehabilitation (2007). Guidelines for pulmonary rehabilitation programs. In: ZuWallack RZ, Crouch R (eds.) Human Kinetics, Champaign, IL 3rd edn

    Google Scholar 

  37. ZuWallack RL, Patel K, Reardon JZ, Clark BA, Normandin EA (1991) Predictors of improvement in the 12-minute walking distance following a six-week outpatient pulmonary rehabilitation program. Chest 99:805–808

    CAS  Google Scholar 

  38. American Thoracic Society/American College of Chest Physicians (2003) ATS/ACCP statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med 167:211–277

    Google Scholar 

  39. Sala E, Roca J, Marrades RM, Alonso J, Gonzalez De Suso JM, Moreno A, Barbera JA, Nadal J, DE Jover L, Rodriguez-Roisin R, Wagner PD (1999) Effects of endurance training on skeletal muscle bioenergetics in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 159:1726–1734

    CAS  PubMed  Google Scholar 

  40. Bernard S, Whittom F, LeBlanc P, Jobin J, Belleau R, Berube C, Carrier G, Maltais F (1999) Aerobic and strength training in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 159:896–900

    CAS  PubMed  Google Scholar 

  41. Maltais F, LeBlanc P, Simard C, Jobin J, Berube C, Bruneau J, Carrier L, Belleau R (1996) Skeletal muscle adaptation to endurance training in patients with chronic obstructive ­pulmonary disease. Am J Respir Crit Care Med 154:442–447

    CAS  PubMed  Google Scholar 

  42. Puhan MA, Scharplatz M, Troosters T, Steurer J (2005) Respiratory rehabilitation after acute exacerbation of COPD may reduce risk for readmission and mortality – a systematic review. Respir Res 6:54

    PubMed  Google Scholar 

  43. Emery CF, Leatherman NE, Burker EJ, MacIntyre NR (1991) Psychological outcomes of a pulmonary rehabilitation program. Chest 100:613–617

    CAS  PubMed  Google Scholar 

  44. Emery CF, Schein RL, Hauck ER, MacIntyre NR (1998) Psychological and cognitive outcomes of a randomized trial of exercise among patients with chronic obstructive ­pulmonary disease. Health Psychol 17:232–240

    CAS  PubMed  Google Scholar 

  45. O’Donnell DE, McGuire M, Samis L, Webb KA (1995) The impact of exercise reconditioning on breathlessness in severe chronic airflow limitation. Am J Respir Crit Care Med 152:2005–2013

    PubMed  Google Scholar 

  46. Green RH, Singh SJ, Williams J, Morgan MD (2001) A randomised controlled trial of four weeks versus seven weeks of pulmonary rehabilitation in chronic obstructive pulmonary disease. Thorax 56:143–145

    CAS  PubMed  Google Scholar 

  47. Plankeel JF, McMullen B, MacIntyre NR (2005) Exercise outcomes after pulmonary rehabilitation depend on the initial mechanisms of exercise limitation among non-oxygen-dependent COPD patients. Chest 127(1):110–116

    PubMed  Google Scholar 

  48. Rossi G, Florini F, Romagnoli M, Bellatone T, Lucic S, Lugli D, Clini E (2005) Length and clinical effectiveness of pulmonary rehabilitation in outpatients with chronic airway obstruction. Chest 127:105–109

    PubMed  Google Scholar 

  49. Lacasse Y, Brosseau L, Milne S, Martin S, Wong E, Guyatt GH, Goldstein RS (2002) Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 3:CD003793

    Google Scholar 

  50. Ringbaek TJ, Broendum E, Hemmingsen L, Lybeck K, Nielsen D, Andersen C, Lange P (2000) Rehabilitation of patients with chronic obstructive pulmonary disease. Exercise twice a week is not sufficient! Respir Med 94:150–154

    CAS  PubMed  Google Scholar 

  51. Puente-Maestu L, Sanz ML, Sanz P, Cubillo JM, Mayol J, Casaburi R (2000) Comparison of effects of supervised versus self-monitored training programs in patients with chronic obstructive pulmonary disease. Eur Respir J 15:517–525

    CAS  PubMed  Google Scholar 

  52. Vallet G, Ahmaidi S, Serres I, Fabre C, Bourgouin D, Desplan J, Varray A, Prefaut C (1997) Comparison of two training programmes in chronic airway limitation patients: standardized versus individualized protocols. Eur Respir J 10:114–122

    CAS  PubMed  Google Scholar 

  53. Punzal PA, Ries AL, Kaplan RW, Prewitt LM (1991) Maximum intensity exercise training in patients with chronic obstructive pulmonary disease. Chest 100:618–623

    CAS  PubMed  Google Scholar 

  54. Horowitz MB, Littenberg B, Mahler DA (1996) Dyspnea ratings for prescribing exercise intensity in patients with COPD. Chest 109:1169–1175

    CAS  PubMed  Google Scholar 

  55. Clark CJ, Cochrane L, Mackay E (1996) Low intensity peripheral muscle conditioning improves exercise tolerance and breathlessness in COPD. Eur Respir J 9:2590–2596

    CAS  PubMed  Google Scholar 

  56. Normandin EA, McCusker C, Connors M, Vale F, Gerardi D, ZuWallack RL (2002) An evaluation of two approaches to exercise conditioning in pulmonary rehabilitation. Chest 121:1085–1091

    PubMed  Google Scholar 

  57. Gosselink R, Troosters T, Decramer M (1998) Effects of exercise training in COPD patients; interval versus endurance training. Eur Respir J 12:2S

    Google Scholar 

  58. Lake FR, Henderson K, Briffa T, Openshaw J, Musk AW (1990) Upper-limb and lower-limb exercise training in patients with chronic airflow obstruction. Chest 97:1077–1082

    CAS  PubMed  Google Scholar 

  59. Couser JI Jr, Martinez FJ, Celli BR (1993) Pulmonary rehabilitation that includes arm exercise reduces metabolic and ventilatory requirements for simple arm elevation. Chest 103:37–41

    PubMed  Google Scholar 

  60. Epstein SK, Celli BR, Martinez FJ, Couser JI, Roa J, Pollock M, Benditt JO (1997) Arm training reduces the VO2 and VE cost of unsupported arm exercise and elevation in chronic obstructive pulmonary disease. J Cardiopulm Rehabil 17:171–177

    CAS  PubMed  Google Scholar 

  61. Simpson K, Killian K, McCartney N, Stubbing DG, Jones NL (1992) Randomised controlled trial of weightlifting exercise in patients with chronic airflow limitation. Thorax 47:70–7

    CAS  PubMed  Google Scholar 

  62. Spruit MA, Gosselink R, Troosters T, De Paepe C, Decramer M (2002) Resistance versus endurance training in patients with COPD and skeletal muscle weakness. Eur Respir J 19:1072–1078

    CAS  PubMed  Google Scholar 

  63. O’Shea SD, Taylor NF, Paratz J (2004) Peripheral muscle strength training in COPD: a systematic review. Chest 126:903–914

    PubMed  Google Scholar 

  64. Lareau SC, Insel KC (2000) Chapter 6. Patient and family education. In: Hodgkin JE, Celli BR, Connors GL (eds) Pulmonary rehabilitation, Human Kinetics, Champaign, IL 3rd edn

    Google Scholar 

  65. Bandura A (1977) Self-efficacy: toward a unifying theory of behavioral change. Psychol Rev 84:191–215

    CAS  PubMed  Google Scholar 

  66. Bodenheimer T, Lorig K, Holman H, Grumbach K (2002) Patient self-management of chronic disease in primary care. JAMA 288(19):2469–2475

    PubMed  Google Scholar 

  67. Bourbeau J, Nault D, Dang-Tan T (2004) Self-management and behaviour modification in COPD. Patient Educ Couns 53:271–277

    Google Scholar 

  68. Donaldson GC, Seemungal TA, Bhowmik A, Wedzicha JA (2002) Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax 57:847–852

    CAS  PubMed  Google Scholar 

  69. Spruit MA, Gosselink R, Troosters T, Kasran A, Gayan-Ramirez G, Bogaerts P, Bouillon R, Decramer M (2003) Muscle force during an acute exacerbation in hospitalized patients with COPD and its relationship with CXCL8 and IGF-I. Thorax 59(9):741–2

    Google Scholar 

  70. Seemungal TA, Donaldson GC, Paul EA, Bestall JC, Jefferies DJ, Wedzicha JA (1998) Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 157:1418–1422

    CAS  PubMed  Google Scholar 

  71. Andersson F, Borg S, Jansson SA, Jonsson AC, Ericsson A, Prutz C et al (2002) The costs of exacerbations in chronic obstructive pulmonary disease. Respir Med 96:700–708

    CAS  PubMed  Google Scholar 

  72. Price MJ, Hurrell C (1999) Health care costs of treating exacerbations of COPD. Eur Respir J 14(Suppl 30):S380

    Google Scholar 

  73. Connors AF Jr, Dawson NV, Thomas C, Harrell FE Jr, Desbiens N, Fulkerson WJ, Kussin P, Bellamy P, Goldman L, Knaus WA (1996) Outcomes following acute exacerbation of severe chronic obstructive lung disease. Am J Respir Crit Care Med 154(4 pt 1):959–67

    PubMed  Google Scholar 

  74. Wilkinson T, Donaldson G, Hurst J, Seemungal T, Wedzicha J (2004) Early therapy improves outcomes of exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 169:1298–1303

    PubMed  Google Scholar 

  75. Bourbeau J, Julien M, Maltais F, Rouleau M, Beaupre A, Begin R, Renzi P, Nault D, Borycki E, Schwartzman K, Singh R, Collet JP (2003) Chronic obstructive pulmonary disease axis of the respiratory network Fonds de la Recherche en Sante du Quebec. Reduction of hospital utilization in patients with chronic obstructive pulmonary disease. Arch Int Med 163(5):585–91

    Google Scholar 

  76. Hefner JE, Fahy B, Hilling L, Barbieri C (1996) Attitudes regarding advance directives among patients in pulmonary rehabilitation. Am J Respir Crit Care Med 154:1735–1740

    Google Scholar 

  77. Heffner JE (2000) Role of pulmonary rehabilitation in palliative care. Respir Care 45(11):1371–1375

    Google Scholar 

  78. Gosselink R (2003) Controlled breathing and dyspnea in patients with chronic obstructive pulmonary disease. J Rehabil Res Develop 40:25–34

    Google Scholar 

  79. Jones AP, Rowe BH (2000) Bronchopulmonary hygiene physical therapy for chronic obstructive pulmonary disease and bronchiectasis. Cochrane Database Syst Rev 2:CD000045

    Google Scholar 

  80. Organization WH (2003) Adherence to long-term therapies: evidence for action. Annex 1:143

    Google Scholar 

  81. Troosters T, Gosselink R, Decramer M (2000) Short- and long-term effects of outpatient rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial. Am J Med 109(3):207–12

    CAS  PubMed  Google Scholar 

  82. Engelen MPKJ, Schols AMWJ, Baken WC, Wesseling GJ, Wouters EF (1994) Nutritional depletion in relation to respiratory and peripheral skeletal muscle function in outpatients with COPD. Eur Respir J 7:1793–1797

    CAS  PubMed  Google Scholar 

  83. Schols AMWJ, Soeters PB, Dingemans AMC, Mostert R, Frantzen PJ, Wouters EF (1993) Prevalence and characteristics of nutritional depletion in patients with stable COPD eligible for pulmonary rehabilitation. Am Rev Respir Dis 147:1151–1156

    CAS  PubMed  Google Scholar 

  84. Schols AMWJ, Fredrix EW, Soeters PB, Westerterp KR, Wouters EFM (1991) Resting energy expenditure in patients with chronic obstructive pulmonary disease. Am J Clin Nutr 5:983–987

    Google Scholar 

  85. Engelen MPKJ, Schols AMWJ, Heidendal GAK, Wouters EFM (1998) Dual-energy X-ray absorptiometry in the clinical evaluation of body composition and bone mineral density in patients with chronic obstructive pulmonary disease. Am J Clin Nutr 68:1298–1303

    CAS  PubMed  Google Scholar 

  86. Mostert R, Goris A, Weling-Scheepers C, Wouters EF, Schols AM (2000) Tissue depletion and health related quality of life in patients with chronic obstructive pulmonary disease. Respir Med 94(9):859–867

    CAS  PubMed  Google Scholar 

  87. Schols AM, Slangen J, Volovics L, Wouters EF (1998) Weight loss is a reversible factor in the prognosis of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 157(6 Pt 1):1791–1797

    CAS  PubMed  Google Scholar 

  88. Wilson DO, Rogers RM, Wright EC, Anthonisen NR (1989) Body weight in chronic obstructive pulmonary disease. The National Institutes of Health Intermittent Positive-Pressure Breathing Trial. Am Rev Respir Dis 139(6):1435–1438

    CAS  PubMed  Google Scholar 

  89. Landbo C, Prescott E, Lange P, Vestbo J, Almdal TP (1999) Prognostic value of nutritional status in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160(6):1856–1861

    CAS  PubMed  Google Scholar 

  90. Steiner MC, Barton RL, Singh SJ, Morgan MD (2003) Nutritional enhancement of exercise performance in chronic obstructive pulmonary disease: a randomised controlled trial. Thorax 58(9):745–751

    CAS  PubMed  Google Scholar 

  91. Efthimiou J, Fleming J, Gomes C, Spiro SG (1988) The effect of supplementary oral nutrition in poorly nourished patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 137(5):1075–1082

    CAS  PubMed  Google Scholar 

  92. Franssen FM, Broekhuizen R, Janssen PP, Wouters EF, Schols AM (2004) Effects of whole-body exercise training on body composition and functional capacity in normal-weight patients with COPD. Chest 125(6):2021–2028

    PubMed  Google Scholar 

  93. Schols AM, Soeters PB, Mostert R, Pluymers RJ, Wouters EF (1995) Physiologic effects of nutritional support and anabolic steroids in patients with chronic obstructive pulmonary disease. A placebo-controlled randomized trial. Am J Respir Crit Care Med 152:1268–1274

    CAS  PubMed  Google Scholar 

  94. Casaburi R, Bhasin S, Cosentino L, Porszasz J, Somfay A, Lewis MI et al (2004) Effects of testosterone and resistance training in men with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 170(8):870–878

    PubMed  Google Scholar 

  95. Singer HK, Ruchinskas RA, Riley KC (2001) The psychological impact of end-stage lung disease. Chest 120:1246–1252

    CAS  PubMed  Google Scholar 

  96. Mills TL (2001) Comorbid depressive symptomatology: isolating the effects of chronic medical conditions on self-reported depressive symptoms among community-dwelling older adults. Soc Sci Med 53:569–578

    CAS  PubMed  Google Scholar 

  97. Yohannes AM, Baldwin RC, Connolly MJ (2003) Prevalence of sub-threshold depression in elderly patients with chronic obstructive pulmonary disease. Int J Geriatr Psychiatry 18(5):412–416

    PubMed  Google Scholar 

  98. Lacasse Y, Rousseau L, Maltais F (2001) Prevalence of depressive symptoms and depression in patients with severe oxygen-dependent Chronic Obstructive Pulmonary Disease. J Cardiopulm Rehabil 21(2):80–86

    CAS  PubMed  Google Scholar 

  99. Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67:361–70

    CAS  PubMed  Google Scholar 

  100. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J (1961) An inventory for measuring depression. Arch Gen Psychiatry 4:561–571

    CAS  PubMed  Google Scholar 

  101. Pulmonary rehabilitation (1999) American thoracic society. Am J Respir Crit Care Med 159(5 Pt 1):1666–82

    Google Scholar 

  102. Strijbos JH et al (1996) A comparison between an outpatient hospital-based pulmonary rehabilitation program and a home-care pulmonary rehabilitation program in patients with COPD. A follow-up of 18 months. Chest 109(2):366–72

    CAS  PubMed  Google Scholar 

  103. Lareau SC, Meek PM, Press D, Anholm JD, Roos PJ (1999) Longitudinal assessment of dyspnea in patients with chronic obstructive pulmonary disease. Heart Lung 28:65–73

    CAS  PubMed  Google Scholar 

  104. Garcia-Aymerich J, Lange P, Benet M, Schnohr P, Anto JM (2006 Sep) Regular physical activity reduces hospital admission and mortality in chronic obstructive pulmonary disease: a population based cohort study. Thorax 61(9):772–778

    CAS  PubMed  Google Scholar 

  105. Pitta F, Troosters T, Probst VS, Spruit MA, Decramer M, Gosselink R (2005) Characteristics of physical activities in daily life in COPD. Am J Respir Crit Care Med 171:972–977

    PubMed  Google Scholar 

  106. Pitta F, Troosters T, Probst VS, Spruit MA, Decramer M, Gosselink R (2006 Mar) Physical activity and hospitalization for exacerbation of COPD. Chest 129(3):536–44

    PubMed  Google Scholar 

  107. Garcia-Aymerich J, Felez MA, Escarrabill J, Marrades RM, Morera J, Elosua R, Anto JM (2004 Oct) Physical activity and its determinants in severe chronic obstructive pulmonary disease. Med Sci Sports Exerc 36(10):1667–73

    PubMed  Google Scholar 

  108. Sewell L, Singh S, Williams J, Collier R, Morgan M (2005) Can individualized rehabilitation improve functional indenendence in elderly patients with COPD? Chest 128:1194–1200

    Google Scholar 

  109. Bowen JB, Votto JJ, Thrall RS, Campbell M, Stockdale-Woolley R, Bandyopadhyay T, ZuWallack R (2000) Functional status and survival following pulmonary rehabilitation. Chest 118:697–703

    CAS  PubMed  Google Scholar 

  110. Ringbaek TJ, Lange P (2005 May) Outdoor activity and performance status as predictors of survival in hypoxaemic chronic obstructive pulmonary disease (COPD). Clin Rehabil 19(3):331–8

    PubMed  Google Scholar 

  111. Garcia-Aymerich J, Lange P, Benet M, Schnohr P, Anto JM (2006 Sep) Regular physical activity reduces hospital admission and mortality in chronic obstructive pulmonary disease: a population based cohort study. Thorax 61(9):772–8

    CAS  PubMed  Google Scholar 

  112. Raskin J, Spiegler P, McCusker C, ZuWallack R, Bernstein M, Busby J, DiLauro P, Griffiths K, Haggerty M, Hovey L, McEvoy D, Reardon JZ, Stavrolakes K, Stockdale-Woolley R, Thompson P, Trimmer G, Youngson L (2006) he effect of pulmonary rehabilitation on healthcare utilization in chronic obstructive pulmonary disease: the northeast pulmonary rehabilitation consortium. J Cardiopulm Rehabil 26:231–6

    PubMed  Google Scholar 

  113. Puhan MA, Scharplatz M, Troosters T, Steurer J (2005) Respiratory rehabilitation after acute exacerbation of COPD may reduce risk for readmission and mortality – a systematic review. Respir Res 6:54

    PubMed  Google Scholar 

  114. O’Donnell DE, Revill SM, Webb KA (2001) Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 164:770–777

    PubMed  Google Scholar 

  115. Cooper CB (2006 Oct) The connection between chronic obstructive pulmonary disease symptoms and hyperinflation and its impact on exercise and function. Am J Med 119(10 Suppl 1):21–31

    PubMed  Google Scholar 

  116. Porszasz J, Emtner M, Goto S, Somfay A, Whipp BJ, Casaburi R (2005) Exercise training decreases ventilatory requirements and exercise-induced hyperinflation at submaximal intensities in patients with COPD. Chest 128:2025–34

    PubMed  Google Scholar 

  117. Casaburi R, Patessio A, Ioli F, Zanaboni S, Donner CF, Wasserman K (1991) Reductions in exercise lactic acidosis and ventilation as a result of exercise training in patients with obstructive lung disease. Am Rev Respir Dis 143:9–18

    CAS  PubMed  Google Scholar 

  118. Puente-Maestu L, Sanz ML, Sanz P, Ruiz de Ona JM, Rodriguez-Hermosa JL, Whipp BJ (2000) Effects of two types of training on pulmonary and cardiac responses to moderate exercise in patients with COPD. Eur Respir J 15:1026–1032

    CAS  PubMed  Google Scholar 

  119. Maltais F, LeBlanc P, Jobin J (1997) Intensity of training and physiological adaptation in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 155:555–561

    CAS  PubMed  Google Scholar 

  120. O’Donnell DE, Voduc N, Fitzpatrick M, Webb KA (2004) Effect of salmeterol on the ventilatory response to exercise in COPD. Eur Respir J 24(1):86–94

    PubMed  Google Scholar 

  121. Maltais F, Hamilton A, Marciniuk D, Hernandez P, Sciurba FC, Richter K, Kesten S, O’Donnell D (2005 Sep) Improvements in symptom-limited exercise performance over 8 h with once-daily tiotropium in patients with COPD. Chest 128(3):1168–78

    CAS  PubMed  Google Scholar 

  122. Appleton S, Smith B, Veale A, Bara A (2002) Long-acting beta2-agonists for chronic obstructive pulmonary disease. Cochrane Database Syst Rev 3:CD001104

    Google Scholar 

  123. O’Donnell DE, Lam M, Webb KA (1998) Measurement of symptoms, lung hyperinflation, and endurance during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 158:1557–1565

    PubMed  Google Scholar 

  124. O’Donnell DE, Lam M, Webb KA (1999) Spirometric correlates of improvement in exercise performance after anticholinergic therapy in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160:542–549

    PubMed  Google Scholar 

  125. Saey D, Debigare R, LeBlanc P, Mador MJ, Cote CG, Jobin J, Maltais F (2003) Contractile leg fatigue after cycle exercise. A factor limiting exercise in patients with COPD. Am J Respir Crit Care Med 168:425–430

    PubMed  Google Scholar 

  126. Casaburi R, Kukafka D, Cooper CB, Witek TJ, Kesten S (2005) Improvement in exercise tolerance with the combination of tiotropium and pulmonary rehabilitation in patients with COPD. Chest 127:809–817

    CAS  PubMed  Google Scholar 

  127. The Nocturnal Oxygen Therapy Group (1980) Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease. Ann Intern Med 93:391–398

    Google Scholar 

  128. Medical Research Council Working Party (1981) Long term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema. Lancet 8222:681–686

    Google Scholar 

  129. Bradley JM, O’Neill B (Oct 2005) Short-term ambulatory oxygen for chronic obstructive pulmonary disease. Cochrane Database Syst Rev 19(4):CD004356

    Google Scholar 

  130. LaCasse Y, Lecours R, Pelletier C, Begin R, Maltais F (2005) Randomised trial of ambulatory oxygenin oxygen-dependent COPD. Eur Respir J 25:1032–1038

    CAS  PubMed  Google Scholar 

  131. Somfay A, Porszasz J, Lee SM, Casaburi R (2001) Dose-response effect of oxygen on hyperinflation and exercise endurance in nonhypoxemic COPD patients. Eur Respir J 18:77–84

    CAS  PubMed  Google Scholar 

  132. Rooyackers JM, Dekhuijzen PNR, Van Herwaarden CLA, Folgering HTM (1997) Training with supplemental oxygen in patients with COPD and hypoxemia at peak exercise. Eur Respir J 10:1278–1284

    CAS  PubMed  Google Scholar 

  133. Garrod R, Paul EA, Wedzicha JA (2000) Supplemental oxygen during pulmonary rehabilitation in patients with COPD with exercise hypoxaemia. Thorax 55:539–543

    CAS  PubMed  Google Scholar 

  134. Wadell K, Henriksson-Larsen K, Lundgren R (2001) Physical training with and without oxygen in patients with chronic obstructive pulmonary disease adn exercise-induced hypoxaemia. J Rehab Med 33:200–205

    CAS  Google Scholar 

  135. Emtner M, Porszasz J, Burns M, Somfay A, Casaburi R (2003) Benefits of supplemental oxygen in exercise training in nonhypoxemic chronic obstructive pulmonary disease patients. Am J Respir Crit Care Med 168:1034–1042

    PubMed  Google Scholar 

  136. Ries AL, Kaplan RM, Limberg TM, Prewitt LM (1995) Effects of pulmonary rehabilitation on physiologic and psychosocial outcomes in patients with chronic obstructive pulmonary disease. Ann Intern Med 122:823–832

    CAS  PubMed  Google Scholar 

  137. Brooks D, Krip B, Mangovski-Alzamora S, Goldstein RS (2002) The effect of postrehabilitation programmes among individuals with chronic obstructive pulmonary disease. Eur Respir J 20:20–29

    CAS  PubMed  Google Scholar 

  138. Ries AL, Kaplan RM, Myers R et al (2003) Maintenance after pulmonary rehabilitation in chronic lung disease: a randomized trial. Am J Respir Crit Care Med 167:880–888

    PubMed  Google Scholar 

  139. Troosters T, Gosselink R, Decramer M (2000) Short- and long-term effects of outpatient rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial. Am J Med 109(3):207–12

    CAS  PubMed  Google Scholar 

  140. Guyatt GH, Berman LB, Townsend M, Pugsley SO, Chambers LW. (1987) A measure of quality of life for clinical trials in chronic lung disease. Thorax 42:773–778.

    CAS  PubMed  Google Scholar 

  141. Reardon J, Awad E, Normandin E, Vale F, Clark B, and ZuWallack RL (1994) The effect of comprehensive outpatient pulmonary rehabilitation on dyspnea. Chest 105:1046–1052.

    CAS  PubMed  Google Scholar 

  142. ZuWallack RZ, Crouch R editors (2004) American Association of Cardiovascular and Pulmonary Rehabilitation. Guidelines for pulmonary rehabilitation programs, 3rd edition, Human Kinetics 2004.

    CAS  PubMed  Google Scholar 

  143. ZuWallack R, Lareau S, Meek P. (2004) The effect of pulmonary rehabilitation on dyspnea. In Lung biology in health and disease: Dyspnea. Mahler D, editor. New York:Marcel Decker, Inc.

    CAS  PubMed  Google Scholar 

  144. Lacasse Y, Brosseau L, Milne S, Martin S, Wong E, Guyatt GH, Goldstein RS. (2002) Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. (3):CD003793.

    CAS  PubMed  Google Scholar 

  145. Lacasse Y, Wong E, Guyatt GH et al. (1996) Meta-analysis of respiratory rehabilitation in chronic obstructive pulmonary disease. Lancet 348:1115–1119

    CAS  PubMed  Google Scholar 

  146. Haggerty MC, Stockdale-Woolley R, ZuWallack R. (1999) Functional status in pulmonary rehabilitation participants. J Cardiopulmonary Rehabil 19:35–42.

    CAS  PubMed  Google Scholar 

  147. Griffiths TL, Burr ML, Campbell IA et al. (2000) Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial. Lancet 355:362–368.

    CAS  PubMed  Google Scholar 

  148. Griffiths TL, Phillips CJ, Davies S et al. (2001) Cost effectiveness of an outpatient multidisciplinary pulmonary rehabilitation programme. Thorax 56:779-784

    CAS  PubMed  Google Scholar 

  149. California Pulmonary Rehabilitation Collaborative Group. Effects of pulmonary rehabilitation on dyspnea, quality of life and health care costs in California. J Cardiopulmonary Rehabil 2004; 24:52–62.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Linda Nici .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Lan, C.K., Nici, L., Wallack, R.Z. (2011). Pulmonary Rehabilitation. In: Hanania, N., Sharafkhaneh, A. (eds) COPD. Respiratory Medicine. Humana Press. https://doi.org/10.1007/978-1-59745-357-8_10

Download citation

  • DOI: https://doi.org/10.1007/978-1-59745-357-8_10

  • Published:

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-949-9

  • Online ISBN: 978-1-59745-357-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics