Skip to main content
SpringerLink
Log in

Musculoskeletal Neoplasms: An Introduction

  • Chapter
  • First Online:
Book cover Bone Pathology

  • 3232 Accesses

Abstract

Our understanding of the biology of tumors, approach to their diagnosis, and management strategies has dramatically evolved over the decades and basic science research as well as clinical outcomes studies continue to add to the existing knowledge. This chapter outlines the current approach to musculoskeletal tumors including their diagnosis, staging, biopsy, and management strategies as well as zone-specific approach to limb tumors including discussion on pathologic fractures.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Hosalkar HS, Dormans JP. Limb sparing surgery for pediatric musculoskeletal tumors. Pediatr Blood Cancer. 2004 Apr; 42(4):295–310.

    Article  PubMed  Google Scholar 

  2. Enneking WF. Staging musculoskeletal tumors. In: Enneking WF, editor. Musculoskeletal tumor surgery. New York: Churchill Living­stone; 1983. pp 68–88.

    Google Scholar 

  3. Hosalkar HS, Torbert JT, Carolan G, Lackman RD. Musculoskeletal tumors. In: Chin KR, Mehta SM, editors. Key Review Concepts. Philadelphia: Wolters Kluver/ Lippincott Williams and Wilkins; 2007.

    Google Scholar 

  4. Enneking W. Surgical prodcedures. In: Enneking WF, editor. Musculoskeletal tumor surgery. New York: Churchill Livingstone; 1983. pp 89–122.

    Google Scholar 

  5. Zeegen EN, Aponte-Tinao LA, Hornicek FJ, Gebhardt MC, Mankin HJ. Survivorship analysis of 141 modular metallic endoprostheses at early follow-up. Clin Orthop Relat Res. 2004 March; 420:239–250.

    Article  PubMed  Google Scholar 

  6. Enneking WF. Modification of the System for Functional Evaluation of Surgical Management of Musculoskeletal Tumors. In: Enneking WF, editor. Limb Salvage in Musculoskeletal Oncology. New York: Churchill Livingstone; 1987. pp 626–639.

    Google Scholar 

  7. Mankin HJ, Gebhardt MC, Jennings LC, et al. Long-term results of allograft replacement in the management of bone tumors. Clin Orthop Relat Res. 1996; 324:86–97.

    Article  PubMed  Google Scholar 

  8. Torbert JT, Fox EJ, Hosalkar HS, Ogilvie CM, Lackman RD. Endoprosthetic reconstructions: results of long-term follow-up of 139 patients. Clin Orthop Relat Res. 2005 Sep; 438:51–9.

    Article  PubMed  Google Scholar 

  9. Ogilvie CM, Torbert JT, Hosalkar HS, Fox EJ, Lackman RD. Incidence and outcomes of early infection after endoprosthetic reconstruction. The University of Pennsylvania Orthop J. 2004; 17:31–33.

    Google Scholar 

  10. Kotz R, Pongracz N, Fellinger EJ, Ritschl P. Uncemented hinge prostheses with reinsertion of the ligamentum patellae. In: Yamamuro T, editor. New developments for limb salvage in musculoskeletal tumours. New York: Springer Verlag; 1989. pp 605–10.

    Chapter  Google Scholar 

  11. Bini SA, Johnston JO, Martin DL. Compliant prestress fixation in tumor prostheses: interface retrieval data. Orthopedics. 2000; 23:707–12.

    PubMed  CAS  Google Scholar 

  12. Barrack RL, Lyons TR, Ingraham RQ, Johnson JC. The use of a modular rotating hinge component in salvage revision total knee arthroplasty. J Arthroplasty. 2000 Oct; 15(7):858–66.

    Article  PubMed  CAS  Google Scholar 

  13. Abboud JA, Patel RV, Donthineni-Rao R, Lackman RD. Proximal tibial segmental prosthetic replacement without the use of muscle flaps. Clin Orthop Relat Res. 2003; 414:189–196.

    Article  PubMed  Google Scholar 

  14. Hosalkar HS, Dormans JP. Surgical management of pelvic sarcoma in children. J Am Acad Orthop Surg. 2007 Jul; 15(7):408–24. Review.

    PubMed  Google Scholar 

  15. Enneking W. Pelvis. In: Enneking WF, editor. Musculoskeletal tumor surgery. New York: Churchill Livingstone; 1983. pp 483–529.

    Google Scholar 

  16. Conrad EU, Springfield D, Peabody TD. Pelvis. In: Simon MA, Springfield D, editors. Surgery for bone and soft-tissue tumors. Philadelphia: Lippincott-Raven Publishers; 1998. pp 323–341.

    Google Scholar 

  17. Springfield D. Autograft reconstructions. Orthop Clin North Am. 1996; 27:483–492.

    PubMed  CAS  Google Scholar 

  18. Dormans JP. Limb-salvage surgery versus amputation for children with extremity sarcomas. In: Herring JA, Birch JG, editors. The child with a limb deficiency. Rosemont, IL: American Academy of Orthopaedic Surgeons; 1998. pp 289–302.

    Google Scholar 

  19. Takami M, Ieguchi M, Takamatsu Ket-al.,. Functional evaluation of flail hip joint after periacetabular resection of the pelvis. Osaka City Med J. 1997; 43:173–183.

    PubMed  CAS  Google Scholar 

  20. Conrad EU, Springfield D, Peabody TD. Pelvis. In: Simon MA, Springfield D, editors. Surgery for bone and soft-tissue tumors. Philadelphia: Lippincott-Raven Publishers; 1998. pp 323–341.

    Google Scholar 

  21. Aboulafia AJ, Buch R, Mathews Jet-al., Reconstruction using the saddle prosthesis following excision of primary and metastatic periacetabular tumors. Clin Orthop. 1995; 314:203213.

    PubMed  Google Scholar 

  22. Malawer M. Periacetabular resections. In: Malawer MM, Sugarbaker PH, editors. Musculoskeletal cancer surgery. Norwell, Massachusetts: Kluwer Academic Publishers; 2001. pp 425–438.

    Google Scholar 

  23. Lackman RD, Torbert JT, Hosalkar HS, Fox EJ, Ogilvie CM. Treatment of Metastases to the Extremities and Pelvis. In Operative Techniques in Orthopedics, Elsevier Inc, Philadelphia. 2004.

    Google Scholar 

  24. Ward WG, Holsenbeck S, Dorey FJ, et al. Metastatic disease of the femur: surgical treatment. Clin Orthop. 2003; 415 (suppl):S230–S244.

    PubMed  Google Scholar 

  25. Hardman PD, Robb JE, Kerr GR, et al. The value of internal fixation and radiotherapy in the management of upper and lower limb bone metastases. Clin Oncol. (R Coll Radiol) 1992; 4:244–248.

    Article  CAS  Google Scholar 

  26. Mirels H: Metastatic disease in long bones. A proposed scoring system for diagnosing impending pathologic fractures. Clin Orthop. 1989; 249:256–264.

    PubMed  Google Scholar 

  27. Jacofsky DJ, Papagelopoulos PJ, Sim FH: Advances and challenges in the surgical treatment of metastatic bone disease. Clin Orthop. 2003; 415 (suppl):S14–S18.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Orthopedic Surgery, Rady Children’s Hospital, School of Medicine, University of San Diego, California, CA, USA

    Harish S. Hosalkar

  2. Department of Orthopaedics, Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Jennifer Goebel

  3. Department of Pathology, Temple Univesity School of Medicine, Philadelphia, PA, 19140, USA

    Jasvir S. Khurana

  4. Department of Orthopaedic Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, USA

    Richard D. Lackman

Authors
  1. Harish S. Hosalkar
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jennifer Goebel
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jasvir S. Khurana
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Richard D. Lackman
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Richard D. Lackman .

Editor information

Editors and Affiliations

  1. Dept. Pathology, Temple University Hospital, N. Broad St. 3401, Philadelphia, 19140, U.S.A.

    Jasvir S. Khurana

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Humana Press, a part of Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Hosalkar, H.S., Goebel, J., Khurana, J.S., Lackman, R.D. (2009). Musculoskeletal Neoplasms: An Introduction. In: Khurana, J. (eds) Bone Pathology. Humana Press. https://doi.org/10.1007/978-1-59745-347-9_16

Download citation

  • DOI: https://doi.org/10.1007/978-1-59745-347-9_16

  • Published:

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-766-2

  • Online ISBN: 978-1-59745-347-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation