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Cartilage Repair Strategies pp 115–135Cite as

Articular Cartilage Resurfacing Using Synthetic Resorbable Scaffolds

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Abstract

Cartilage repair is a challenging clinical problem because once adult cartilage sustains damage, whether traumatic or pathological, an irreversible, degenerative process can occur (1). The resulting defects may lead to osteoarthritis (2–4). Attempts to repair articular cartilage have included implantation of artificial matrices, growth factors, perichondrium, periosteum, and transplanted cells (5), but to date no reliable, reproducible approach has been identified. Furthermore, repair tissue frequently lacks the physical structure and mechanical properties necessary to ensure long-term efficacy (6). It is reasonable to hypothesize that the inferior mechanical properties of the repair tissue are partially caused by inadequate support during healing.

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Authors and Affiliations

  1. Weill Medical College of Cornell University, New York, NY

    Riley J. Williams III MD (Associate Professor of Orthopaedic Surgery, Attending Orthopaedic Surgeon, Director)

  2. Hospital for Special Surgery, Institute for Cartilage Repair, New York, NY

    Riley J. Williams III MD (Associate Professor of Orthopaedic Surgery, Attending Orthopaedic Surgeon, Director)

  3. OsteoBiologics, Inc, San Antonio, TX

    Gabriele G. Niederauer PhD (Synthetic Resorbable Scaffolds, Director of Research and Development)

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  1. Riley J. Williams III MD
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  2. Gabriele G. Niederauer PhD
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Editors and Affiliations

  1. Weill Medical College of Cornell University, USA

    Riley J. Williams III MD (Associate Professor of Orthopaedic Surgery, Attending Orthopaedic Surgeon Director) (Associate Professor of Orthopaedic Surgery, Attending Orthopaedic Surgeon Director)

  2. Institute for Cartilage Repair, Hospital for Special Surgery, New York, NY

    Riley J. Williams III MD (Associate Professor of Orthopaedic Surgery, Attending Orthopaedic Surgeon Director) (Associate Professor of Orthopaedic Surgery, Attending Orthopaedic Surgeon Director)

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© 2007 Humana Press Inc., Totowa, NJ

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Williams, R.J., Niederauer, G.G. (2007). Articular Cartilage Resurfacing Using Synthetic Resorbable Scaffolds. In: Williams, R.J. (eds) Cartilage Repair Strategies. Humana Press. https://doi.org/10.1007/978-1-59745-343-1_9

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  • DOI: https://doi.org/10.1007/978-1-59745-343-1_9

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-629-0

  • Online ISBN: 978-1-59745-343-1

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