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Diabetes and Exercise pp 163–183Cite as

Diabetes Mellitus and Exercise Physiology in the Presence of Diabetic Comorbidities

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Part of the book series: Contemporary Diabetes ((CDI))

Abstract

While uncomplicated type 2 diabetes mellitus (T2DM) is already associated with an impaired exercise capacity, the presence of other comorbidities appears to further worsen exercise capacity in T2DM. Common diabetic comorbidities such as hypertension, arterial stiffness, cardiovascular disease, systolic dysfunction, diastolic dysfunction, and diabetic nephropathy are all associated with worse exercise capacity in T2DM. Benefits of exercise training programs for those with T2DM and certain comorbidities (e.g., hypertension, increased arterial stiffness, or post-myocardial infarction) have been shown to include improved exercise capacity. Further study is warranted to determine the specific benefits and risks of exercise training in subpopulations of T2DM such as those with T2DM and either congestive heart failure or microvascular complications of diabetes.

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Authors and Affiliations

  1. Division of General Internal Medicine, Department of Medicine, University of Colorado Denver, Aurora, CO, USA

    Amy G. Huebschmann

  2. Divisions of General Internal Medicine and Cardiology, Department of Medicine, University of Colorado Denver, Aurora, CO, USA

    Judith G. Regensteiner

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  1. Amy G. Huebschmann
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  2. Judith G. Regensteiner
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Editors and Affiliations

  1. Divisions of General Internal Medicine and Cardiology, Department of Medicine, University of Colorado Denver, Aurora, CO, USA

    Judith G. Regensteiner PhD

  2. Division of Endocrinology Metabolism and Diabetes, Department of Medicine, Aurora, CO, USA

    Jane E.B. Reusch MD

  3. Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA

    Kerry J. Stewart EDD

  4. Joslin-Beth Israel Deaconess Foot Center, Microcirculation Laboratory, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

    Aristidis Veves MD, DSc

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Huebschmann, A., Regensteiner, J. (2009). Diabetes Mellitus and Exercise Physiology in the Presence of Diabetic Comorbidities. In: Regensteiner, J.G., Reusch, J.E., Stewart, K.J., Veves, A. (eds) Diabetes and Exercise. Contemporary Diabetes. Humana Press. https://doi.org/10.1007/978-1-59745-260-1_8

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