Summary
The clinical indications for CT in patients with asthma include detection of bronchiectasis in patients with suspicion of allergic bronchopulmonary aspergillosis; documentation of the presence and extent of emphysema in smokers with asthma; and identification of conditions, such as hypersensitivity pneumonitis, that may be confused with asthma. However, high-resolution volumetric helical acquisition using MDCT and improvement image analysis techniques have made possible accurate and reproducible quantitative assessment of airway wall and lumen areas and lung density. This may permit the in vivo assessment of the degree of airway wall remodeling and the extent of small airway obstruction. These parameters should become accepted biomarkers for assessing effect of treatments in clinical trials and ultimately in the clinical management of individual patients.
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Grenier, P.A., Beigelman-Aubry, C., Brillet, PY. (2008). Asthma. In: Boiselle, P.M., Lynch, D.A. (eds) CT of the Airways. Contemporary Medical Imaging. Humana Press. https://doi.org/10.1007/978-1-59745-139-0_10
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DOI: https://doi.org/10.1007/978-1-59745-139-0_10
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