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RNA Binding Proteins pp 135–156Cite as

Post-Transcriptional Control of Type-1 Plasminogen Activator Inhibitor mRNA

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Part of the book series: Endocrine Updates ((ENDO,volume 16))

Abstract

In this chapter we will describe the identification of a sequence in the 3’UTR of the type-1 plasminogen activator inhibitor (PAI-1) mRNA that mediates the cyclic nucleotide regulation of mRNA stability. This will be followed by a discussion of the isolation and characterization of a novel RNA-binding protein that interacts with the PAI-1 cyclic nucleotide responsive sequence.

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Author information

Authors and Affiliations

  1. University of Michigan Medical School, Ann Arbor, MI, USA

    Joanne H. Heaton & Thomas D. Gelehrter

Authors
  1. Joanne H. Heaton
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  2. Thomas D. Gelehrter
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Editor information

Editors and Affiliations

  1. Departments of Medicine and Physiology & Biophysics, Georgetown University School of Medicine, Washington, DC, USA

    Kathryn Sandberg Ph.D. (Associate Professor) (Associate Professor)

  2. Department of Physiology & Biophysics, Georgetown University School of Medicine, Washington, DC, USA

    Susan E. Mulroney Ph.D. (Associate Professor) (Associate Professor)

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Heaton, J.H., Gelehrter, T.D. (2002). Post-Transcriptional Control of Type-1 Plasminogen Activator Inhibitor mRNA. In: Sandberg, K., Mulroney, S.E. (eds) RNA Binding Proteins. Endocrine Updates, vol 16. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6446-8_8

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  • DOI: https://doi.org/10.1007/978-1-4757-6446-8_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4419-4935-6

  • Online ISBN: 978-1-4757-6446-8

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