Abstract
Fuel homeostasis is important to the regulation of central nervous system (CNS) function because cerebral pathways of metabolism of glucose, ketone bodies, and amino acids are dependent upon plasma substrate availability. Therefore, brain function and brain metabolism are under nutritional regulation and the interface between diet or fuel homeostasis and brain function is the limiting transport barrier between blood and brain, which is the brain capillary endothelial wall, i.e., the blood-brain barrier (BBB) (Figure 1).
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© 1991 Plenum Press, New York
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Pardridge, W.M. (1991). Blood-Brain Barrier Transport of Glucose, Free Fatty Acids, and Ketone Bodies. In: Vranic, M., Efendic, S., Hollenberg, C.H. (eds) Fuel Homeostasis and the Nervous System. Advances in Experimental Medicine and Biology, vol 291. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5931-9_5
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DOI: https://doi.org/10.1007/978-1-4684-5931-9_5
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