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Guidance of Neural Crest Migration

Latex Beads as Probes of Surface—Substratum Interactions

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The Cell Surface in Development and Cancer

Part of the book series: Developmental Biology ((DEBO,volume 3))

Abstract

The vertebrate neural crest is first recognizable at the onset of neurulation as the neural folds appose to form the neural tube. Neural crest cells emigrate from the dorsal neural tube shortly after tube closure. From this site of origin, they migrate extensively and differentiate into a wide variety of derivatives. Neural crest-derived cell types include neurons and supportive cells of the peripheral nervous system, melanocytes, several neurosecretory cell types, bone and car tilage of the face, and adrenal chromaffin cells. Because of the migratory ability of neural crest cells and the diversity of crest derivatives, this transient embryonic structure provides an important model system for studying interactions involved in cell movement and differentiation.

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© 1986 Plenum Press, New York

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Bronner-Fraser, M. (1986). Guidance of Neural Crest Migration. In: Steinberg, M.S. (eds) The Cell Surface in Development and Cancer. Developmental Biology, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5050-7_15

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  • DOI: https://doi.org/10.1007/978-1-4684-5050-7_15

  • Publisher Name: Springer, Boston, MA

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