Summary
The ovarian cycle of the common marmoset (Callithrix jacchus) is intermediate with those of laboratory rats and human beings. There are also qualitative and quantitative similarities between preovulatory granulosa cell function in marmosets and women. Cyclic and acyclic (reproductively suppressed) marmoset ovaries are packed with multiple immature follicles, and these contain granulosa cells which respond biochemically and morphologically to human FSH in vitro. Hormonedependent differentiation can, therefore, be studied systematically using primary cell cultures, the strategy which has contributed so much to current concepts of nonprimate folliculogenesis. Our experience establishes the marmoset monkey as a valid laboratory model for studies of cellular aspects of folliculogenesis in primates.
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© 1987 Plenum Press, New York
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Hillier, S.G., Harlow, C.R., Shaw, H.J., Wickings, E.J., Dixson, A.F., Hodges, J.K. (1987). Granulosa Cell Differentiation in Primate Ovaries: The Marmoset Monkey (Callithrix Jacchus) as a Laboratory Model. In: Stouffer, R.L. (eds) The Primate Ovary. Serono Symposia, USA. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9513-7_5
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DOI: https://doi.org/10.1007/978-1-4615-9513-7_5
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