Skip to main content

The chemoprevention of prostate cancer and the prostate cancer prevention trial

  • Chapter
Book cover Diagnosis and Treatment of Genitourinary Malignancies

Part of the book series: Cancer Treatment and Research ((CTAR,volume 88))

Abstract

The impact of prostate cancer is substantial, and this fact is often cited as the reason for aggressive screening for and aggressive treatment of the disease. There are, of course, significant uncertainties regarding the efficacy of both prostate cancer screening and prostate cancer treatment [1]. Indeed, both are active areas of investigation, and the goal of reducing prostate cancer morbidity and mortality continues to elude modern medicine. An approach deserving consideration is the chemoprevention of prostate cancer.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Woolf SH (1995). N Engl J Med 333:1401–1405.

    Article  CAS  Google Scholar 

  2. Sporn MB, Dunlop NM, Newton DL (1976). Fed Proc 35:1332–1338.

    CAS  Google Scholar 

  3. Lippman SM, Benner SE, Ki Hong W (1994). J Clin Oncol 12:851–873.

    CAS  Google Scholar 

  4. Feigl P, Blumenstein B, Thompson IM, Crowley J, Wolf M, Kramer BS, Coltman C, Brawley OW, Ford LG (1995). Controlled Clin Trials 16:150–163.

    Article  CAS  Google Scholar 

  5. Brawley OW, Ford LG, Thompson IM, Perlman JA, Kramer BS (1994). Cancer Epidemiol Biomarkers Prev 3:177–182.

    CAS  Google Scholar 

  6. Thompson IM, Feigl P, Coltman C (1995). In Chemoprevention of Prostate Cancer with Finasteride, DeVita V, Hellman S, Rosenberg S (eds), vol. 5, pp. 57–76.

    Google Scholar 

  7. Sporn MB (1991). Cancer Res 51:6215–6218.

    CAS  Google Scholar 

  8. Pienta KJ, Esper PS (1993). Ann Intern Med 118:793–803.

    Article  CAS  Google Scholar 

  9. Meikle AW, Smith JA (1996). Urol Clin North Am 17:709–718.

    Google Scholar 

  10. Shimizu H, Ross RK, Bernstein L, Yatani R, Henderson BE, Mack TM (1991). Br J Cancer 963–966.

    Google Scholar 

  11. Muir CS, Nectoux J, Staszewski J (1991). Acta Oncol 30:133–140.

    Article  CAS  Google Scholar 

  12. Flanders WD (1984). Prostate 5:621–629.

    Article  CAS  Google Scholar 

  13. Sakr WA, Haas GP, Cassin BF, Pontes JE, Crissman JD (1993). J Urol 150:379–385.

    CAS  Google Scholar 

  14. Heby O (1981). Differentiation 19:1–20.

    Article  CAS  Google Scholar 

  15. Heston WDW, Kadmon D, Lazan (1982). Prosate 3:383–389.

    Article  CAS  Google Scholar 

  16. Dunn JE (1975). Cancer Res 35:3240–3245.

    CAS  Google Scholar 

  17. Haenszel W, Kurihoro M (1969). J Natl Cancer Inst 40:43–68.

    Google Scholar 

  18. Yu H, Harris RE, Gao R, Wynder EL (1991). Int J Epidemiol 20:76–81.

    Article  CAS  Google Scholar 

  19. Muir CS, Nectoux J, Staszewski J (1991). Acta Oncol 30:133–140.

    Article  CAS  Google Scholar 

  20. Pienta KJ, Esper PS (1993). J Natl Cancer Inst 85:1538–1541.

    Article  CAS  Google Scholar 

  21. Kolonel LN, Nomura AMY, Hinds MW, Hirohata T, Hankin JH, Lee J (1983). Cancer Res 43:(Suppl)2397–2402.

    Google Scholar 

  22. Lew EA, Garfinkel L (1979). J Chron Dis 32:563–576.

    Article  CAS  Google Scholar 

  23. Severson RK, Grove JS, Nomura AM, Stemmerman GN (1988). Br Med J 297:713–715.

    Article  CAS  Google Scholar 

  24. Kaul L, Heshmat MY, Kovi J, Jackson MA, Jackson AG, Jones GW (1987). Nutr Cancer 9:123–128.

    Article  CAS  Google Scholar 

  25. Severson RK, Nomura AMY, Grove JS, Stemmermann GN (1989). Cancer Res 49:1857–1860.

    CAS  Google Scholar 

  26. Berg JW (1975). Cancer Res 35:3345–3350.

    CAS  Google Scholar 

  27. Armstrong B, Doll R (1975). Int J Cancer 15:617–631.

    Article  CAS  Google Scholar 

  28. Rose DP, Boyar, AP, Wynder EL (1986). Cancer 58:2363–2371.

    Article  CAS  Google Scholar 

  29. Rotkin ID (1977). Cancer Treat Rep 61:173–180.

    CAS  Google Scholar 

  30. Hutchinson GB (1976). Semin Oncol 3:151–159.

    Google Scholar 

  31. Slattery ML, Schumacher MC, West DW, Robinson LM, French TK (1990). Am J Clin Nutr 52:752–757.

    CAS  Google Scholar 

  32. Snowdon DA, Phillips RL, Choi W (1984). Am J Epidemiol 120:244–250.

    CAS  Google Scholar 

  33. Mettlin C, Selenskas S, Natarajan N, Huben R (1989). Cancer 64:605–612.

    Article  CAS  Google Scholar 

  34. Mills PK, Beeson WL, Phillips RL, Fraser GE (1989). Cancer 64:598–604.

    Article  CAS  Google Scholar 

  35. Hirayama T (1979). Natl Cancer Inst Monogr 53:149–155.

    Google Scholar 

  36. Heshma MY, Kaul L, Kovi J, Jackson MA, Jackson AG, Jones GW (1985). Prostate 6:7–17.

    Article  Google Scholar 

  37. Ohno Y, Yoshida O, Oishi K, Yamabe H, Schroeder F (1988). Cancer Res 48:1331–1336.

    CAS  Google Scholar 

  38. Kolonel LN, Hinds MW, Nomura AMY, Hankin JH, Lee J (1985). Natl Cancer Inst Monogr 69:137–142.

    CAS  Google Scholar 

  39. Graham S, Haughey B, Marshall J, et al. (1983). J Natl Cancer Inst 70:687–692.

    CAS  Google Scholar 

  40. Kolonel LN, Yoshizawa CN, Hankin JH (1988). Am J Epidemiol 127:999–1012.

    CAS  Google Scholar 

  41. Anderson S, Berman DM, Jenkins EP, Russell DW (1991). Nature 354:159.

    Article  Google Scholar 

  42. Kadoham N, Karr JP, Murphy GP, Sandberg AA (1984). Cancer Res 44:4947–4954.

    Google Scholar 

  43. Pollard M, Luckert PH, Sporn MB (1996). Cancer Res 51:3610–3611.

    Google Scholar 

  44. Slawn K, Kadmon D, Park SH (1996). Cancer Res 53:4461–4465.

    Google Scholar 

  45. Schwartz GG, Hulka BS (1990). Anticancer Res 10:1307–1312.

    CAS  Google Scholar 

  46. Wynder ER, Mabuchi K, Whitmore W (1971). Cancer 28:344–368.

    Article  CAS  Google Scholar 

  47. Hovenian MS, Deming CL (1948). Surg Gynecol Obstet 86:29–35.

    Google Scholar 

  48. Huggins C, Hodges CV (1941). Cancer Res 1:293–297.

    CAS  Google Scholar 

  49. Ross RK (1990). Proc Annu Meet Am Assoc Cancer Res 31:457–458.

    Google Scholar 

  50. Montie JE, Pienta KJ (1994). Urology 43:892–899.

    Article  CAS  Google Scholar 

  51. Meikle W, Stanish WM (1982). J Clin Endocrinol Metab 54:1104–1108.

    Article  CAS  Google Scholar 

  52. Ghanadian R, Puah KM, O’Donohue EPM (1979). Br J Cancer 39:696–699.

    Article  CAS  Google Scholar 

  53. Hammond GL, Kontturi M, Vihko R (1978). Clin Endocrinol 9:113–121.

    Article  CAS  Google Scholar 

  54. Comstock GW, Gordon GB, Hsing AW (1993). Cancer Epidemiol Biomarkers Prev 2:219–221.

    CAS  Google Scholar 

  55. Barrett-Connor E, Garland C, McPhillips JB, Khaw KT, Wingard DL (1990). Cancer Res 50:169–173.

    CAS  Google Scholar 

  56. Meikle AW, Smith JA, Stringham JD (1987). Prostate 10:25–31.

    Article  CAS  Google Scholar 

  57. Ross RK, Berstein L, Judd H, Hanisch R, Pike M, Henderson B (1986). J Natl Cancer Inst 76:45–48.

    CAS  Google Scholar 

  58. Ross RK, Berstein L, Lobo RA, Shimizu H, Stanczyk FZ, Pike M (1992). Lancet 339:887–889.

    Article  CAS  Google Scholar 

  59. Hamalainen E, Adlercreutz H, Puska P (1984). J Steroid Biochem 20:459–464.

    Article  CAS  Google Scholar 

  60. Coffey DS (1979). Geneva Int Union Against Cancer 48:4–23.

    CAS  Google Scholar 

  61. Noble RL (1959). Cancer Res 19:1125–1139.

    CAS  Google Scholar 

  62. Bruning PF, Bonfrer JMG (1989). Cancer Res 46:2606–2609.

    Google Scholar 

  63. Street C, Howell RJS, Perry L (1989). Acta Endocrinol 120:175–179.

    CAS  Google Scholar 

  64. Pusater DJ, Roth WT, Ross JK, Shultz TD (1990). Am J Clin Nutr 51:371–377.

    Google Scholar 

  65. Kyprianou N, Isaacs JT (1988). Endocrinology 122:552–562.

    Article  CAS  Google Scholar 

  66. Nobel RL (1977). Cancer Res 37:1929.

    Google Scholar 

  67. Shirai T, Tamano S, Kato T, Iwasaki S, Takahashi S, Ito N (1991). Cancer Res 51:1264–1269.

    CAS  Google Scholar 

  68. Grino P, Griffin J, Wilson J (1990). Endocrinology 126:1165–1172.

    Article  CAS  Google Scholar 

  69. Geller J (1990). J Clin Endocrinol Metab 71:1552–1555.

    Article  CAS  Google Scholar 

  70. Petersen RE, Imperato-McGinley J, Gautier T, Sturla E (1977). Am J Med 62:170–191.

    Article  Google Scholar 

  71. Imperato-McGinley J, Guerrero L, Gautier T, Petersen RE (1974). Science 186:1213–1215.

    Article  CAS  Google Scholar 

  72. McConnell JD, Wilson J, George FW, Geller J, Pappas F, Stoner E (1992). J Clin Endocrinol Metab 74:505–508.

    Article  CAS  Google Scholar 

  73. Gormley G, Stoner E, Bruskewitz R, et al. (1992). N Engl J Med 327:1185–1191.

    Article  CAS  Google Scholar 

  74. Petrow V, Padilla GM, Mukherji S, Marts SA (1984). J Pharm Pharamacol 36:352–353.

    Article  CAS  Google Scholar 

  75. Bologna M, Muzi P, Biordi L, Pestuccia CV (1992). Current Therapeut Res 5:799–813.

    Google Scholar 

  76. Damber JE, Bergh A, Daehlin L, Petrov V, Landstrom M (1992). Prostate 20:187–190.

    Article  CAS  Google Scholar 

  77. Lamb JC, English H, Levandoski PL, Rhodes GR, Johnson RK, Isaacs JR (1992). Endocrinology 130:685–694.

    Article  CAS  Google Scholar 

  78. Brooks JR, Berman C, Nguyen H (1991). Prostate 18:215–227.

    Article  CAS  Google Scholar 

  79. Tsukamoto S, Adaza H, Imada S, Koiso K, Tomoyuki S, Ideyama Y, Kudo M (1995). J Natl Cancer Inst 87:842–843.

    Article  CAS  Google Scholar 

  80. Presti JC, Fair WR, Andriole G, Sogani PC, Seidman FD, Ng J, Gormley G (1992). J Urol 148:1201–1204.

    Google Scholar 

  81. Andriole G, Lieber MD, Smith JA, et al. (1995). Urology 45:491–497.

    Article  CAS  Google Scholar 

  82. Stoner E, The Finasteride Study Group (1994). Urology 43:284–294.

    Article  CAS  Google Scholar 

  83. Rittmaster R (1994). N Engl J Med 330:120–125.

    Article  CAS  Google Scholar 

  84. Thompson IM, Coltman C, Brawley OW, Ryan A (1995). Semin Urol 13:122–129.

    CAS  Google Scholar 

  85. Guess HA, Heyse JF, Gormley G (1993). Prostate 22:31–37.

    Article  CAS  Google Scholar 

  86. Stoner E, Round E, Ferguson D, Gormley G, The Finasteride Study Group (1994). J Urol 151:1296–1300.

    CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer Science+Business Media New York

About this chapter

Cite this chapter

Brawley, O.W., Thompson, I.M. (1996). The chemoprevention of prostate cancer and the prostate cancer prevention trial. In: Pienta, K.J. (eds) Diagnosis and Treatment of Genitourinary Malignancies. Cancer Treatment and Research, vol 88. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6343-3_11

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-6343-3_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7913-3

  • Online ISBN: 978-1-4615-6343-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics