Abstract
Human butyrylcholinesterase (BuChE; EC.3.1.1.8) is directed by a single gene 1–3. The BCHE gene is polymorphic (cf. other papers in this book) and some of its alleles produce plasma BuChE allozymes with abnormal kinetic properties. Though no physiological function has yet been assigned to this enzyme, it is of pharmacological importance since plasma BuChE is involved in the hydrolysis of various ester-containing drugs 4. Moreover this enzyme has proven to be an efficient scavenger to protect against organophosphate poisons 5
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© 1992 Springer Science+Business Media New York
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Masson, P., Adkins, S., Pham-Trong, P., Lockridge, O. (1992). Expression and Refolding of Functional Human Butyrylcholinesterase from E. Coli . In: Shafferman, A., Velan, B. (eds) Multidisciplinary Approaches to Cholinesterase Functions. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3046-6_6
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DOI: https://doi.org/10.1007/978-1-4615-3046-6_6
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