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Sequence Alignment of Esterases and Lipases Based on 3-D Structures of Two Members of This Family

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Multidisciplinary Approaches to Cholinesterase Functions

Abstract

Acetylcholinesterases (AChE, EC 3.1.1.7) and butyrylcholinesterases (BChE, EC 3.1.1.8) from various organisms show a high degree of sequence similarity. They have been identified as members of a family of homologous proteins which includes other esterases (carboxylesterases and cholesterol esterases), lipases, and non-enzymatic domains of other proteins such as thyroglobulin (Krejci et al.,1991; Gentry and Doctor, 1991).

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© 1992 Springer Science+Business Media New York

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Cygler, M. et al. (1992). Sequence Alignment of Esterases and Lipases Based on 3-D Structures of Two Members of This Family. In: Shafferman, A., Velan, B. (eds) Multidisciplinary Approaches to Cholinesterase Functions. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3046-6_15

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  • DOI: https://doi.org/10.1007/978-1-4615-3046-6_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6328-6

  • Online ISBN: 978-1-4615-3046-6

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