Abstract
Although an uncommon malignancy, carcinoma of the gallbladder is the fifth most common cancer of the gastrointestinal tract and the most common cancer of the biliary tract [1]. The diagnosis of gallbladder carcinoma is made incidentally at the time of exploration in 1% of patients undergoing surgical treatment for cholelithiasis [1,2]. Carcinoma of the gallbladder is more common in females, three fourths of the patients being women with a median age in the seventh decade. In most patients, the disease is advanced and unresectable. The overall prognosis, therefore, is rather dismal, with 5year survival rates of less than 5% reported in most large published series [1–27]. However, in a small group of early lesions, surgery provides a reasonable probability of long-term survival. Radiation and chemotherapy have mostly a palliative role in the treatment of gallbladder carcinoma, and the experience with these treatment modalities is derived from their use in a rather limited number of patients.
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Wanebo, H.J., Vezeridis, M.P. (1994). Treatment of gallbladder cancer. In: Sugarbaker, P.H. (eds) Hepatobiliary Cancer. Cancer Treatment and Research, vol 69. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2604-9_10
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DOI: https://doi.org/10.1007/978-1-4615-2604-9_10
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