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Ayurvedic Science of Food and Nutrition pp 49–58Cite as

Integrating the Science and Art of Using Food as Medicine

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Abstract

The domestication of agriculture approximately 10,000 years ago led to profound environmental changes that have influenced our diet and lifestyle. This has resulted in a global pandemic of nutrition- and lifestyle-related chronic degenerative diseases arising from a mismatch between our ancient genetic makeup and current lifestyle patterns. While conventional medicine tries to address chronic disease by symptom management, newer paradigms, such as integrative and functional medicine, attempt to identify the root cause of chronic diseases. Disease is described as a complex phenomenon comprised of core clinical imbalances in various organ systems and physiological processes resulting from the interplay of environmental inputs such as diet and lifestyle. Nutrition, as determined by dietary patterns consisting of foods with bioactive compounds, is critically involved in the creation and mitigation of disease primarily by disrupting or restoring balance or homeostasis in cellular mechanisms and products. Food serves as an information molecule, directly or indirectly influencing gene expression. Individual genetic predispositions in turn dictate unique dietary needs and requirements. Normalizing multiple biological systems requires a multipronged approach that includes a gradual transition to an unprocessed whole foods diet, knowing and learning about food sources, removing or controlling food allergens, reducing the environmental toxic burden, and following a holistic lifestyle intervention strategy that combines diet, exercise, stress management, and spirituality.

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References

  1. Aguilera JM (2013) Healthy habits. In: Edible structures. The basic science of what we eat. CRC Press/Taylor and Francis Group, Boca Raton, pp 349–365

    Google Scholar 

  2. Neustadt J (2006) Western diet and inflammation. Integr Med 5(4):14–18

    Google Scholar 

  3. Cordain L, Gotshall LW, Boyd Eaton S, Boyd Eaton III S (1998) Physical activity, energy expenditure and fitness. An evolutionary perspective. Int J Sports Med 19:328–335

    Article  CAS  Google Scholar 

  4. Eaton SB, Cordain L (1997) Evolutionary aspects of diet: old genes, new fuels. In: Simopoulos P (ed) Nutrition and fitness: evolutionary aspects, children’s health, programs and policies. Karger, Basel, pp 26–37

    Chapter  Google Scholar 

  5. Nesse RM, Williams JC (1998) Evolution and the origins of disease. Sci Am 279(5):86–89

    Article  CAS  Google Scholar 

  6. Shaw JE, Sicree RA, Zimmet PZ (2010) Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 87:4–14

    Article  CAS  Google Scholar 

  7. Popkin BM (2006) Global nutrition dynamics: the world is shifting rapidly toward a diet linked with non-communicable diseases. Am J Clin Nutr 84:289–298

    CAS  Google Scholar 

  8. Delavari M, Sonderlund AL, Swinburn B, Mellor D, Renzaho A (2013) Acculturation and obesity among migrant populations in high income countries- a systematic review. BMC Public Health 13:458. doi:10.1186/1471-2458-13-458

    Article  Google Scholar 

  9. Hu FB (2011) Globalization of diabetes: the role of diet, lifestyle and genes. Diabetes Care 34(6):1249–1257. doi:10.2337/dc11-0442

    Article  Google Scholar 

  10. Pruss-Ustun A, Vickers C, Haefliger P, Bertollini R (2011) Known and unknowns on burden of disease due to chemicals: a systematic review. Environ Health 10:9, http://www.ehjournal.net/content/10/1/9

    Article  Google Scholar 

  11. Borchers A, Teuber SS, Keen CL, Gershwin ME (2010) Food safety. Clin Rev Allergy Immunol 39:95–141. doi:10.1007/S12016-009-81764

    Article  CAS  Google Scholar 

  12. Gentschew L, Ferguson LR (2012) Role of nutrition and microbiota in susceptibility to inflammatory diseases. Mol Nutr Food Res 56:524–535

    Article  CAS  Google Scholar 

  13. Malarkey WB, Jarjoura D, Klatt M (2013) Workplace based mindfulness practice and inflammation: a randomized trial. Brain Behav Immun 27:145–154, http://dx.doi.org/10.1016/j.bbi.2012.10.009

    Article  Google Scholar 

  14. Jones DS, Hoffman L, Quinn S (2009) 21st century medicine: a new model for medical education and practice. Institute for Functional Medicine, Gig Harbor, http://www.functionalmedicine.org/ifm_ecommerce/ProductDetails.aspx?ProductID=174

    Google Scholar 

  15. di Sarsina PR, Iseppato I (2011) Why we need integrative medicine? EPMA J 2:5–7. doi:10.1007/s13167-011-0065-2

    Article  Google Scholar 

  16. Maizes V, Rakel D, Niemiec C (2009) Integrative medicine and patient -centered care. Explore 5(5):277–289

    Article  Google Scholar 

  17. Chang C (2013) Is integrative medicine the next frontier? Clin Rev Allergy Immunol 44(3):205–7. doi:10.1007/S12016-012-8313-3

    Google Scholar 

  18. Hyman M (2004) Paradigm shift: the end of “normal science” in medicine. Understanding function in nutrition, health and disease. Altern Ther 10(5):10–15, 90–94

    Google Scholar 

  19. Cloninger CR (2011) Person centered integrative care. J Eval Clin Pract 17:371–372

    Article  Google Scholar 

  20. Rastogi S (2009) Ayurveda for comprehensive healthcare. Indian J Med Ethics 6(2):101–2

    Google Scholar 

  21. DeBusk R (2010) The role of nutritional genomics in developing an optimal diet for humans. Nutr Clin Pract 25(6):627–633

    Article  Google Scholar 

  22. Trajillo E, Davis C, Milner J (2006) Nutrigenomics, proteomics, metabolomics, and the practice of dietetics. J Am Diet Assoc 106:403–413

    Article  Google Scholar 

  23. Stover PJ, Caudill M (2008) Genetic and epigenetic contributions to human nutrition and health: managing genome-diet interactions. J Am Diet Assoc 108(9):1480–1487

    Article  Google Scholar 

  24. Fenech M, El-Sohemy A, Cahill L, Ferguson LR, French TA, Tai ES, Milner J, Koh WP, Xie L, Zucker M, Buckley M, Cosgrove L, Lockett T, Fung KY, Head R (2011) Nutrigenetics and nutrigenomics: viewpoints on the current status and applications in nutrition research and practice. J Nutrigenet Nutrigenomics 4:69–80

    Article  CAS  Google Scholar 

  25. Feinberg AP (2008) Epigenetics at the epicenter of modern medicine. JAMA 299(11):1345–1350. doi:10.1001/jama.299.11.1345

    Article  CAS  Google Scholar 

  26. Waterland RA, Garza C (1999) Potential mechanisms of metabolic imprinting that lead to chronic disease. Am J Clin Nutr 69:179–197

    CAS  Google Scholar 

  27. SzarcvelSzic K, Ndlovu MN, Haegeman G, VandenBerghe W (2010) Nature or nurture: let food be your epigenetic medicine in chronic inflammatory disorders. Biochem Pharmacol 80:1816–1832

    Article  CAS  Google Scholar 

  28. Belshaw NJ, Johnson IT (2011) Isothiocyanates and polyphenols. In: Niculescu MD, Haggerty P (eds) Nutrition in epigenetics. Wiley-Blackwell, Ames, pp 263–272

    Chapter  Google Scholar 

  29. Ong TP, Moreno FS, Ross SA (2011) Targeting the epigenome with bioactive food components for cancer prevention. J Nutrigenet Nutrigenomics 4:275–292

    Article  CAS  Google Scholar 

  30. Verma M (2012) Cancer control and prevention by nutrition and epigenetic approaches. Antioxid Redox Signal 17(2):355–364

    Article  CAS  Google Scholar 

  31. Richard Lord JAB (ed) (2008) Laboratory evaluations for integrative and functional medicine, 2nd edn. Metametrix Institute, Duluth

    Google Scholar 

  32. Ames BN (2010) Optimal micronutrients delay mitochondrial decay and age associated diseases. Mech Ageing Dev 131(7–8):473–479

    Article  CAS  Google Scholar 

  33. Ames BN (2006) Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage. Proc Natl Acad Sci USA 103(47):17589–17594

    Google Scholar 

  34. Jacobs DR, Tapsell LC, Temple NJ (2011) Food synergy: the key to balancing the nutrition research effort. Public Health Rev 33(2):507–529

    Google Scholar 

  35. Asmis R, Llorente VC, Gey KF (1995) Prevention of cholesteryl ester accumulation in p388D1 macrophage like cells by increased cellular vitamin E depends on species of extracellular cholesterol. Conventional heterologous non-human cell cultures are poor models of human atherosclerotic foam cell formation. Eur J Biochem 233:171–178

    Article  CAS  Google Scholar 

  36. Albert CM, Cook NR, Gaziano JM, Zaharris E, MacFadyen J, Danileson E (2008) Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: a randomized trial. JAMA 299:2027–2036

    Article  CAS  Google Scholar 

  37. Sauer J, Mason JB, Choi Sang-Woon (2009) Too much folate- a risk factor for cancer and cardiovascular disease? Curr Opin Clin Nutr Metab Care 12(1):30–36. doi:10.1097/MCO.0b0 13e 32831cec62

    Article  CAS  Google Scholar 

  38. Wang S, Meckling KA, Marcone MF, Kakuda Y, Tsao R (2011) Synergistic, additive and antagonistic effects of food mixtures on total antioxidant capacities. J Agric Food Chem 59:960–968

    Article  CAS  Google Scholar 

  39. Jacobs DR et al (2009) Food synergy: an operational concept for understanding nutrition. Am J Clin Nutr 89:1543S–1548S

    Article  CAS  Google Scholar 

  40. Messina M, Lampe JW, Birt DF, Appel LJ, Pivonka E, Berry B, Jacobs DR Jr (2001) Reductionism and the narrowing nutrition perspective: time for reevaluation and emphasis on food synergy. J Am Diet Assoc 101(12):1416–1419

    Article  CAS  Google Scholar 

  41. Jacobs DR, Tapsell LC (2007) Food, not nutrients is the fundamental unit in nutrition. Nutr Rev 65(10):439–450

    Article  Google Scholar 

  42. Jacobs SR, Tapsell LC (2013) Food synergy: the key to a healthy diet. Plenary lecture II conference on “translating nutrition: integrating research, practice and policy”. Proc Nutr Soc 72:200–206. doi:10.1017/S0029665112003011

  43. Morie N, Hirabayashi N, Takahashi Y, Miyauchi Y, Taguchi H, Takeishi K (2005) Synergistic effect of green tea catechins on cell growth and apoptosis induction in gastric carcinoma cells. Biol Pharm Bull 28:574–579

    Article  Google Scholar 

  44. Govindarajan R, Vijayakumar M, Pushpangadan P (2005) Antioxidant approach to disease management and the role of Rasayana herbs of Ayurveda. J Ethnopharmacol 99:165–178

    Article  CAS  Google Scholar 

  45. Vasanthi HR, Parameswari RP (2010) Indian spices for a healthy heart-an overview. Curr Cardiol Rev 6:274–279

    Article  CAS  Google Scholar 

  46. Jungbauer A, Medjakovic S (2012) Anti-inflammatory properties of culinary herbs and spices that ameliorate the effects of metabolic syndrome. Maturitas 71:227–239

    Article  CAS  Google Scholar 

  47. Hlavačková L, Janegová A, Uličná O, Janega P, Cerná A, Babál P (2011) Spice up the hypertension diet-curcumin and piperine prevent remodeling of aorta in experimental L-NAME induced hypertension. Nutr Metab (Lond) 8:72. doi:10.1186/1743-7075-8-72

    Article  Google Scholar 

  48. Hu FB (2002) Dietary pattern analysis: a new direction in nutritional epidemiology. Curr Opin Lipidol 13:3–9

    Article  CAS  Google Scholar 

  49. Mano R, Ishida A, Ohya Y, Todoriki H, Takishita S (2009) Dietary intervention with Okinawan vegetables increased circulating endothelial progenitor cells in healthy young women. Atherosclerosis 204:544–548

    Article  CAS  Google Scholar 

  50. Estruch R, Ros E, Salas-Salvadó J, Covas MI, Corella D, Arós F, Gómez-Gracia E, Ruiz-Gutiérrez V, Fiol M, Lapetra J, Lamuela-Raventos RM, Serra-Majem L, Pintó X, Basora J, Muñoz MA, Sorlí JV, Martínez JA, Martínez-González MA (2013) Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med 368(14):1279–1290. doi:10.1056/NEJMoa1200303, Epub 2013 Feb 25

    Article  CAS  Google Scholar 

  51. Foroughi M, Akhavanzanjani M, Maghsoudi Z, Ghiasvand R, Khorvash F, Askari G (2013) Stroke and nutrition: a review of studies. Int J Prev Med 4(Suppl 2):S165–S179

    Google Scholar 

  52. Bosscher D, Breynaert A, Pieters L, Hermans N (2009) Food based strategies to modulate the composition of the intestinal microbiota and their associated health effects. J Physiol Pharmacol 60(Suppl 6):5–11

    Google Scholar 

  53. Murray M (2006) Altered CYP, expression and function in response to dietary factors: potential roles in disease pathogenesis. Curr Drug Metab 7(1):67–81

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. David B Falk College of Sport and Human Dynamics, Department of Public Health, Food Studies and Nutrition, Syracuse University, Syracuse, NY, USA

    Sudha Raj

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  1. Sudha Raj
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Correspondence to Sudha Raj .

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Editors and Affiliations

  1. PG Department of Kaya Chikitsa, State Ayurvedic College, Lucknow, India

    Sanjeev Rastogi

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Raj, S. (2014). Integrating the Science and Art of Using Food as Medicine. In: Rastogi, S. (eds) Ayurvedic Science of Food and Nutrition. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9628-1_5

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