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Sleep Deprivation and Rheumatologic Disease

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Sleep Deprivation and Disease

Abstract

Sixty-three percent of Americans are not meeting their sleep needs. Symptoms of sleep deprivation (insufficient sleep and poor quality sleep) are common complaints of patients with rheumatologic diseases. Sleep deprivation alters immune function and host defense mechanisms with release of inflammatory cytokines. Pain, fatigue, and depression are associated with sleep deprivation. This review focuses on the role of sleep deprivation in the spectrum of rheumatologic diseases including rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, systemic lupus erythematosus, primary Sjögren’s syndrome, scleroderma, Behcet’s disease, and osteoarthritis.

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  1. Division of Sleep Medicine, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Redwood City, CA, USA

    Vivien C. Abad M.D., M.B.A. & Christian Guilleminault M.D., D.M., D.Biol.

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Correspondence to Vivien C. Abad M.D., M.B.A. .

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  1. Department of Neurology Sleep Division, Harvard Medical School Massachusetts General Hospital, Boston, Massachusetts, USA

    Matt T. Bianchi

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Abad, V.C., Guilleminault, C. (2014). Sleep Deprivation and Rheumatologic Disease. In: Bianchi, M. (eds) Sleep Deprivation and Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9087-6_12

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