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Celiac Disease: Dispelling Misconceptions and Myths

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Celiac Disease

Part of the book series: Clinical Gastroenterology ((CG))

Abstract

Once considered a rare disease among children of northern European decent with classical symptoms of malabsorption, celiac disease (CD) is now known to affect individuals in every decade of life and of many ethnicities and races. The current presentations of CD vary widely from an asymptomatic state to classical symptoms of abdominal pain, bloating, weight loss, diarrhea, and steatorrhea. They may also present along a spectrum with more subtle gastrointestinal and/or extraintestinal symptoms and signs of the disease. High-risk groups include family members of individuals with CD, as well as those with type 1 diabetes and a variety of autoimmune and other diseases. While biopsy remains the gold standard in diagnosis, serological tests are crucial in determining who should undergo endoscopy and biopsy. Currently, a gluten-free diet (GFD) is the only available therapy, and lifelong adherence to this diet is vitally important as continued gluten consumption may predispose patients to complications or associated disorders.

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Authors and Affiliations

  1. Clinical Fellow, Department of Medicine, Division of Gastroenterology, University of California, San Diego, La Jolla, CA, USA

    Erica Boettcher M.D.

  2. Department of Medicine, University of California, 9500 Gilman Drive, Mail Code 0063, San Diego, La Jolla, CA, 92093, USA

    Sheila E. Crowe M.D.

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  1. Erica Boettcher M.D.
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  2. Sheila E. Crowe M.D.
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Correspondence to Sheila E. Crowe M.D. .

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Editors and Affiliations

  1. Department of Medicine, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA

    S. Devi Rampertab

  2. Department of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

    Gerard E. Mullin

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Conflict of Interest

 Dr. S.E.Crowe is a Principal Investigator in the “Clinical Evaluation of Three Celiac Disease-Specific Patient Reported Outcome Instruments in Established and Newly Diagnosed Celiac Disease Patients” study sponsored by Alvine Pharmaceuticals, Inc. She is also the author of Celiac Disease for Dummies and receives royalties from John Wiley & Sons Publishers.

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Boettcher, E., Crowe, S.E. (2014). Celiac Disease: Dispelling Misconceptions and Myths. In: Rampertab, S., Mullin, G. (eds) Celiac Disease. Clinical Gastroenterology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4614-8560-5_17

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