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Geriatric Trauma and Critical Care pp 45–54Cite as

Immunologic

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Abstract

The aging process is associated with functional changes to every organ system within the human body. Immunosenescence refers to changes in the innate and adaptive immune responses associated with increased age. The net clinical effect of these changes increases a patient’s susceptibility to infection, risk of malignancy and autoimmune disease. These changes to the immune system that occur with aging may contribute to increased morbidity and mortality in this population after injury and emergent surgery.

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Authors and Affiliations

  1. Department of Surgery, Division of Trauma, Critical Care, Burns, and Acute Care Surgery, MetroHealth Medical Center, Room H938A, Hamann Bldg 2500 MetroHealth Drive, Cleveland, OH, 44109, USA

    Jeffrey A. Claridge MD, MS, FACS

  2. Northern Ohio Trauma System, Cleveland, OH, USA

    Jeffrey A. Claridge MD, MS, FACS

  3. Department of Surgery, Case Western Reserve University School of Medicine, Cleveland, OH, USA

    Jeffrey A. Claridge MD, MS, FACS

  4. Department of Surgery, MetroHealth Medical Center, Room H938A, Hamann Bldg 2500 MetroHealth Drive, Cleveland, OH, 44109, USA

    Jeffrey A. Claridge MD, MS, FACS & Aman Banerjee MD

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  1. Jeffrey A. Claridge MD, MS, FACS
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Correspondence to Jeffrey A. Claridge MD, MS, FACS .

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  1. Department of Surgery, Lincoln Medical Center, Bronx, New York, USA

    Jay A. Yelon

  2. Department of Surgery, Stritch School of Medicine, Loyola University Medical Center, Maywood, Illinois, USA

    Fred A. Luchette

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Claridge, J.A., Banerjee, A. (2014). Immunologic. In: Yelon, J., Luchette, F. (eds) Geriatric Trauma and Critical Care. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8501-8_6

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