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Endocannabinoids and Monoamines: Modulating the Modulators

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Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders

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Abstract

The past decade has seen a tremendous growth in knowledge related to cannabinoid receptor signaling in brain. In addition, the impact and consequences of cannabinoid modulation of monoaminergic circuits are steadily emerging demonstrating a significant interaction between these two systems in a variety of psychiatric (affective disorders) and neurological disorders (neurodegeneration, pain). Areas to be covered in the accompanying chapters include an overview of the endocannabinoid system, a summary of current cannabinoid receptor nomenclature, and pharmacological principles as well as electrophysiological, biochemical, and behavioral evidence for cannabinoid modulation of dopaminergic, noradrenergic, and serotonergic circuitry.

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Authors and Affiliations

  1. Department of Neuroscience, Farber Institute for Neurosciences, Thomas Jefferson University, 900 Walnut Street, Suite 417, 19107, Philadelphia, PA, USA

    Elisabeth J. Van Bockstaele

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  1. Elisabeth J. Van Bockstaele
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Correspondence to Elisabeth J. Van Bockstaele .

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  1. , Department of Neuroscience, Thomas Jefferson University, Walnut Street 900, Philadelphia, 19147, Pennsylvania, USA

    Elisabeth J. Van Bockstaele

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Van Bockstaele, E. (2013). Endocannabinoids and Monoamines: Modulating the Modulators. In: Van Bockstaele, E. (eds) Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7940-6_1

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