Chapter

Neuropsychology of Children in Africa

Part of the series Specialty Topics in Pediatric Neuropsychology pp 203-214

Date:

Assessing the Effects of Maternal Anemia on Child Development in Benin

  • Florence Bodeau-LivinecAffiliated withIRD UMR 216, Mère et enfant face aux infections tropicalesFaculté de Pharmacie, Université Paris DescartesEcole des Hautes Etudes en Santé Publique Email author 
  • , Michel CotAffiliated withIRD UMR 216, Mère et enfant face aux infections tropicalesFaculté de Pharmacie, Université Paris Descartes
  • , Ghislain K. KouraAffiliated withIRD UMR 216, Mère et enfant face aux infections tropicalesFaculté de Pharmacie, Université Paris Descartes
  • , Michael J. BoivinAffiliated withDepartments of Psychiatry and Neurology/Ophthalmology, Michigan State UniversityDepartment of Psychiatry, Neuropsychology Section

* Final gross prices may vary according to local VAT.

Get Access

Abstract

More than 50 % of women develop moderate anemia during pregnancy with about 5–10 % of women developing severe anemia in Sub-Saharan Africa. Severe anemia increases the risk of mortality and morbidity in mothers, but there is limited information on anemia during pregnancy and cognitive outcome in childhood despite the very high prevalence of anemia in Sub-Saharan Africa. The main goal of this research project is to study the relationship between anemia in pregnancy and cognitive function in childhood. This study takes advantage of a group of infants born following a randomized controlled trial of intermittent preventive treatment for malaria in women during pregnancy funded by the European Union. Mothers have been followed from the second trimester of pregnancy until delivery including at least three blood samples with infections (malaria) and micronutrient deficiencies analyses. Offspring are assessed with the Mullen Scales of Early Learning (MSEL) at 12 months of age. A blood draw is also performed assessing Hb concentration, infections (malaria), iron deficiency, and lead in blood. So far, preliminary results show significant associations between impaired development and both environmental and care giving quality risk factors.