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Taurine 8 pp 51–58Cite as

Effect of Taurine Feeding on Bone Mineral Density and Bone Markers in Rats

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 776))

Abstract

The purpose of this study was to investigate the effect of dietary taurine supplementation on bone mineral density (BMD) and bone mineral content (BMC) in rats. Twenty Sprague–Dawley male rats (body weight 200 ± 10 g) were divided into two groups, control and taurine group (2% taurine-supplemented diet). All rats were fed on experimental diet and deionized water and libitum for 6 weeks. Serum alkaline phosphatase (ALP) activity, osteocalcin, PTH, and urinary deoxypyridinoline cross-links value were measured as markers of bone formation and resorption. BMD and BMC were measured using PIXImus (GE Lunar Co., Wisconsin) in spine and femur. The effect of diet on ALP, osteocalcine, and PTH was not significant. There were no significant differences in ALP, osteocalcine, and PTH concentration. Urinary calcium excretion was lower in taurine group than in control group. Femur BMC/weight of taurine group was significantly higher than control group. The results of this study showed the possible role of taurine in bone metabolism in male rats.

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Abbreviations

ALP:

Alkaline phosphatase

DPD:

Deoxypyridinoline

Tau:

Taurine

DPD/Cr:

Creatinine excretion

BMD:

Bone mineral density

BMC:

Bone mineral content

FER:

Food efficiency ratio

SBMD:

Spine bone mineral density

SBMC:

Spine bone mineral content

FBMD:

Femur bone mineral density

FBMC:

Femur bone mineral content

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Author information

Authors and Affiliations

  1. Department of Food and Nutrition, Keimyung University, 1000 Sindangdong, Dalseogu, Daegu, 704-701, South Korea

    Mi-Ja Choi & Ji-Na Seo

Authors
  1. Mi-Ja Choi
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  2. Ji-Na Seo
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Correspondence to Mi-Ja Choi .

Editor information

Editors and Affiliations

  1. City University of New York, Center for Developmental Neuroscience, College of Staten Island, 2800 Victory Blvd, Staten Island, 10314, New York, USA

    Abdeslem El Idrissi

  2. City University of New York, Department of Biology, College of Staten Island, Victory Blvd 2800, Staten Island, 10314, New York, USA

    William J. L'Amoreaux

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Choi, MJ., Seo, JN. (2013). Effect of Taurine Feeding on Bone Mineral Density and Bone Markers in Rats. In: El Idrissi, A., L'Amoreaux, W. (eds) Taurine 8. Advances in Experimental Medicine and Biology, vol 776. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6093-0_6

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