Abstract
Metastasis. A metastasis arises from the spread of a systemic malignancy or nonadjacent primary central nervous system (CNS) malignancy to the brain or its coverings. Parenchymal metastases account for about half of all brain tumors. The incidence of metastases to brain parenchyma tends to increase with age. Parenchymal metastasis has peak prevalence at 65 years old and a slight predominance in men. Extra-axial metastasis is more common in the pediatric population. Survival of patients with cranial metastasis is dictated by size, number, and location of lesions. Metastasis to the brain parenchyma, however, generally indicates a poor prognosis as most patients who receive whole brain radiation therapy have a median survival of 3–6 months.
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Patel, G.V., Karimi, S., Young, R.J. (2013). Adult Brain Tumors. In: Karimi, S. (eds) Atlas of Brain and Spine Oncology Imaging. Atlas of Oncology Imaging. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5653-7_1
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