Abstract
Among the most investigated are the mechanisms that regulate stem cell function in the nervous and hematopoietic systems. Therefore, hematopoietic stem cells, which give rise to all blood and immune system cells, and neural crest stem cells, which give rise to the peripheral nervous system, are among the best-characterized stem cells. We are just beginning to understand how their functions are regulated. The conserved mechanisms have long been hypothesized as the mode of stem cell regulation. However, testing this requires interdisciplinary approaches. The ultimate goal is to integrate what we know about stem cells in different tissues to understand the extent to which they employ similar or different mechanisms to regulate critical functions. We have focused so far on the mechanisms that regulate stem cell self-renewal, aging, and their role in organogenesis.
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References
Pavlovic M, Balint B (2006) The use of stem cells to repair cardiac tissue. Anest Reanim Transfuziol 34:129–150
Balint B, Pavlovic M (2006) Stem cells—biology, harvesting, extracorporeal purification and some aspects of their clinical application. Bilt Transf 52(2–3):2–10
Balint B, Stamatovic D, Todorovic M, Jevtic M, Ostojic G, Pavlovic M, Lojpur Z, Jocic M (2007) Stem cells in the arrangement of bone marrow repopulation and regenerative medicine. Vojnosanit Pregl 64(7):481–484 (VSP)
Balint B, Pavlovic M, Jevtic M, Hrvacevic R, Ignjatovic L, Mijuskovic Z, Blagojevic R, Trkuljic M (2007) Simple “Closed-cirquit” group–specific immunoadsorption system for ABO–Incompatible kidney transplants. Transfus Apher Sci 36(3):225–233
Pavlovic M (2008) VSELs concept (Review). MNE Medica, No 1, Year I, 16–17, ref. p.43
Pavlovic M, Todorovic M, Todorovic V, Tyagi V, Balint B (2009) Adult stem cell research and regenerative therapy in neurological diseases: limitations and perspectives Part I. Basic research data necessary for understanding stem cell treatment approaches in neuro-regenerative therapy. Anest Reanim Transfuziol 55(1–2):4–14
Pavlovic M, Todorovic M, Todorovic V, Tyagi V, Balint B (2009) Adult stem cell research and regenerative therapy in neurological diseases: limitations and perspectives Part II Neurological diseases and stem cell therapy. Anest Reanim Transfuziol 55(1–2):15–30
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Pavlovic, M., Balint, B. (2013). Stem Cell Renewal and Differentiation. In: Stem Cells and Tissue Engineering. SpringerBriefs in Electrical and Computer Engineering. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5505-9_8
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DOI: https://doi.org/10.1007/978-1-4614-5505-9_8
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