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Genetic Polymorphism of Milk Proteins

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Advanced Dairy Chemistry

Abstract

With the advent of genome analysis and developments in proteomic tools, search for milk protein polymorphisms has exploded and progressively moved from qualitative to quantitative aspects. A great diversity of alleles have been discovered at the six main milk protein loci and significant advances made in understanding the relationship between nucleotide polymorphisms and protein structure and expression. Some demonstrative examples, taken in cattle and goats, will be addressed to illustrate how mutations responsible for polymorphisms at the genomic level can influence milk protein composition, both qualitatively and quantitatively. Although milk fat globule membrane-associated proteins account for only 1–2 % of total milk proteins, evidence that these proteins possess techno-functional and nutritional properties is accumulating and data on their genetic polymorphisms are becoming more consistent. A part of this chapter is also devoted to this issue.

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This article is dedicated to the memory of François Grosclaude on his untimely death.

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  1. Institut National de la Recherche Agronomique, UMR1313, Génétique animale et Biologie intégrative (GABI), Équipe “Lait, Génome & Santé”, Domaine de Vilvert-Bâtiment 221, 78350, Jouy-en-Josas, France

    P. Martin, L. Bianchi, C. Cebo & G. Miranda

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    Paul L. H. McSweeney

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    Patrick F. Fox

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Martin, P., Bianchi, L., Cebo, C., Miranda, G. (2013). Genetic Polymorphism of Milk Proteins. In: McSweeney, P., Fox, P. (eds) Advanced Dairy Chemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-4714-6_15

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