Abstract
Trans-arterial radiotherapy for liver malignancies began with iodine-131 labeled lipiodol for hepatocellular carcinoma (HCC). This agent continues to be used, labeled with 131I as well as with other radionuclides that emit β-particles, notably rhenium-188. Particulates such as glass and albumin microspheres labeled with yttrium-90 have also been utilized, and their physical characteristics have enabled evaluation of their utility in metastatic liver cancers as well, with considerable success.
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Leung, D.K., Divgi, C. (2013). Trans-Arterial I-131 Lipiodol Therapy of Liver Tumors. In: Aktolun, C., Goldsmith, S. (eds) Nuclear Medicine Therapy. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4021-5_12
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