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Glomerular Filtration

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Abstract

Urine is initially an ultrafiltrate of the plasma. Ultrafiltration occurs from the glomerulus (a tuft of capillaries) into the Bowman’s capsule (the blind end of a nephron)—see Fig. 3.1. In moving from the capillary into the Bowman’s capsule, the filtrate must traverse three layers. These are:

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Further Reading

  • Haraldsson B, Nystrom J, Deen WM (2008) Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev 88:451–487

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  • Kriz W, Kaissling B (1992) Structural organization of the mammalian kidney. In: Seldin DW, Giebisch C (eds) The kidney: physiology and pathology. Raven Press, New York

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  • Tryggvason K, Wartiovaara J (2005) How does the kidney filter plasma? Physiology 20:96–101

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  • Verroust PJ, Christensen EI (2002) Megalin and cubilin—the story of two multipurpose receptors unfolds. Nephrol Dial Transplant 17:1867–1871

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© 2012 Springer Science+Business Media New York

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Lote, C.J. (2012). Glomerular Filtration. In: Principles of Renal Physiology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3785-7_3

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  • DOI: https://doi.org/10.1007/978-1-4614-3785-7_3

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-3784-0

  • Online ISBN: 978-1-4614-3785-7

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