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Retinal and Choroidal Manifestations of Selected Systemic Diseases pp 353–376Cite as

Vogt–Koyanagi–Harada Disease

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Abstract

Vogt–Koyanagi–Harada disease is a bilateral granulomatous panuveitis, generally symmetrical, associated to extraocular manifestations such as poliosis, vitiligo, alopecia, central nervous system, and auditory signs. It is considered an autoimmune disease, mediated by T cells, against melanocytes of uveal tract, skin, central nervous system, and inner ear. A genetic predisposition has been suggested. Patients have no history of ocular trauma and no clinical or laboratory evidence of other ocular or systemic disease. Therapy includes early, high doses of systemic steroids. Immunomodulatory therapy has also been used with good results.

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Authors and Affiliations

  1. Inflammatory Eye Disease Clinic, Hospital “Dr. Luis Sánchez Bulnes”, Asociación para Evitar la Ceguera en México. I.A.P. Vicente García Torres, 46, San Lucas Coyoacán, 04030, México, D.F., México

    Maria de Lourdes Arellanes-García M.D., Luz Elena Concha-del-Río M.D. & Maria del Carmen Preciado-Delgadillo M.D., Ph.D.

  2. Departamento de Oftalmología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran, Vasco de Quiroga 15, Seccion XVAI, Tlalpan, Mexico, Distrito Federal, 14000, Mexico

    Claudia Recillas-Gipsert M.D.

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  1. Maria de Lourdes Arellanes-García M.D.
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  2. Luz Elena Concha-del-Río M.D.
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  3. Maria del Carmen Preciado-Delgadillo M.D., Ph.D.
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  4. Claudia Recillas-Gipsert M.D.
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Correspondence to Maria de Lourdes Arellanes-García M.D. .

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  1. Johns Hopkins University, School of Medicine, The Retina Division,Wilmer Eye Institute, Al-Oruba Street, PO Box 7191, Riyadh, 1010, Saudi Arabia

    J. Fernando Arévalo

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de Lourdes Arellanes-García, M., Concha-del-Río, L.E., del Carmen Preciado-Delgadillo, M., Recillas-Gipsert, C. (2013). Vogt–Koyanagi–Harada Disease. In: Arévalo, J. (eds) Retinal and Choroidal Manifestations of Selected Systemic Diseases. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3646-1_19

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