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A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities pp 1–17Cite as

Introduction

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Abstract

We developed these guidelines using drug prescribing information and reviewing the available literature on relevant neuropsychiatric disorders in populations without intellectual disabilities because of the dearth of available ­literature on the population with intellectual disabilities. The idea of combining antiepileptics and mood stabilizers makes sense because there is obvious overlap between what the neurological literature calls antiepileptics and the psychiatric ­literature calls mood stabilizers. Therefore, a total of 21 oral compounds, which are antiepileptics and/or mood stabilizers, were reviewed. In alphabetical order, they are carbamazepine, clonazepam, diazepam, ethosuximide, felbamate, ­gabapentin, lacosamide, lamotrigine, levetiracetam, lithium, lorazepam, oxcarbazepine, phenobarbital, phenytoin, pregabalin, primidone, rufinamide, tiagabine, topiramate, valproate, and zonisamide. In this introduction, we briefly review three concepts, evidence-based medicine, personalized medicine, and drug utilization reviews, in reference to how they have been utilized in these guidelines. The process used in developing these guidelines is then reviewed.

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  1. Department of Psychiatry College of Medicine, University of Kentucky, Lexington, KY, USA

    Jose de Leon

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  1. College of Medicine, Department of Psychiatry, University of Kentucky, West Fourth St. 627, Lexington, 40508, Kentucky, USA

    Jose de Leon

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de Leon, J. (2012). Introduction. In: de Leon, J. (eds) A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-2012-5_1

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  • DOI: https://doi.org/10.1007/978-1-4614-2012-5_1

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