Abstract
Tuberculosis is the most common bacterial infection in the world with approximately two billion people infected (one-third of the world’s population). Treatment of tuberculosis dates back to the discovery that isoniazid (INH), a compound discovered in 1912 and found to be effective in treatment of TB in the 1950s. It is still the most commonly used agent, and with rifampin, a part of all first-line regimens. While INH is still recommended for initial therapy in most cases, resistance to INH has been reported, and therefore initial therapy always involves multiple drugs.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Further Reading
Sia, I. G., & Wieland, M. L. (2011). Current concepts in the management of tuberculosis. Mayo Clin Proc, 86(4), 348–361.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2012 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Finberg, R.W., Guharoy, R. (2012). Clinical Approach to Treatment of Mycobacterial Infections. In: Clinical Use of Anti-infective Agents. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1068-3_18
Download citation
DOI: https://doi.org/10.1007/978-1-4614-1068-3_18
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-1067-6
Online ISBN: 978-1-4614-1068-3
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)