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Breast Cancer Stem Cells

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Advances in Cancer Stem Cell Biology

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Abstract

We now know that some solid neoplasms, such as breast cancer, contain a ­subpopulation of cells with stem cell properties. This subpopulation, also known as cancer stem cells (CSC), could be responsible for the malignant transformation and the progression of the disease (Wicha et al. 2006). This hypothesis could be useful in clinical practice, not only explaining a lot of the remaining questions about the disease behavior, solving the frequent failure to conventional therapies, and defining the future therapeutic approach with the development of novel targeted therapies.

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Author information

Authors and Affiliations

  1. Medical Oncology Unit, Hospital Universitario Infanta Leonor, C/ Gran Vía del Este nº 80, 28031, Madrid, Spain

    Nuria Rodríguez Salas

  2. Surgery Department, Hospital del Henares, Madrid, Spain

    Enrique González González

  3. Pathology Department, Medical School, Autónoma University, Madrid, Spain

    Carlos Gamallo Amat

Authors
  1. Nuria Rodríguez Salas
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  2. Enrique González González
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  3. Carlos Gamallo Amat
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Corresponding author

Correspondence to Nuria Rodríguez Salas .

Editor information

Editors and Affiliations

  1. , Department of Laboratory Medicine, Catholic University, Largo A. Gemelli 8, Rome, 00168, Italy

    Roberto Scatena

  2. School of Medicine, Institute of Biochemistry, Catholic University, Rome, 00168, Italy

    Alvaro Mordente

  3. , Department of Laboratory Medicine, Catholic University, Largo A. Gemelli 8, Rome, 00168, Italy

    Bruno Giardina

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Salas, N.R., González, E.G., Amat, C.G. (2012). Breast Cancer Stem Cells. In: Scatena, R., Mordente, A., Giardina, B. (eds) Advances in Cancer Stem Cell Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0809-3_9

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