Abstract
Primo vessels have been found on various organs of the animals. The liquid in these vessels reveals distinct chemical compositions according to a Âproteomic analysis. A recent study showed the primo vessels to be functioning pathways of cancer metastasis. In this article, we report evidence of tissue healing in the liver via a primo vessel. In the hope that a sudden impact of irreversible electroporation (IRE) on liver tissue could provide a dynamic response by the primo vessel, we employed it to induce apoptosis in ablated lesions, which yielded positive signals in H&E staining and on a TUNEL assay. The ablated regions were observed to draw primo vessels in order to cure the damage. The primo vessels were observed with a Trypan blue technique. In addition, capillaries were observed to have been structurally preserved after applying IRE while another study showed extensive hepatocellular regeneration in the post-IRE stage. These results suggest that the PV appears to contribute to curing the ablated lesions in the liver.
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Kim, HB., Sung, CK., Ahn, S. (2012). Effect of the Primo Vascular System on Liver Tissue Recovery After Irreversible Electroporation: A Preliminary Study. In: Soh, KS., Kang, K., Harrison, D. (eds) The Primo Vascular System. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0601-3_16
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DOI: https://doi.org/10.1007/978-1-4614-0601-3_16
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